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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab170933-100μg |
100μg |
现货 ![]() |
| |
| Ab170933-1mg |
1mg |
现货 ![]() |
| |
| Ab170933-5mg |
5mg |
现货 ![]() |
| |
| Ab170933-10mg |
10mg |
期货 ![]() |
|
| 产品名称 | Belimumab (anti-TNFSF13B), 肿瘤坏死因子配体超家族成员 13B 抑制剂 |
|---|---|
| 别名 | 贝利木单抗 | 贝利木单抗(抗 TNFSF13B) |
| 英文别名 | ApoL related ligand TALL 1 antibody | B cell Activating Factor antibody | B lymphocyte stimulator antibody | B-cell-activating factor antibody | BAFF antibody | BLyS antibody | CD 257 antibody | CD257 antibody | CD257 antigen antibody | Delta BAFF antibod |
| 规格或纯度 | 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA |
| 宿主种属 | 人(Human) |
| 特异性 | TNFSF13B |
| 种属反应性 | 人(Human),小鼠(Mouse) |
| 偶联 | Unconjugated |
| 作用类型 | 抑制剂 |
| 作用机制 | 肿瘤坏死因子配体超家族成员 13B 抑制剂 |
| 克隆类型 | 重组抗体 |
|---|---|
| Format | Whole IgG |
| 亚型 | Human IgG1 |
| 轻链亚型 | lambdaC2 |
| SDS-PAGE | 28.2 kDa (Light Chain) & 52.1 kDa (Heavy Chain), under reducing conditions; 175.9 kDa, under non-reducing conditions. |
| 纯化方法 | Protein A purified |
| 纯度 | >95% |
| 物理外观 | Liquid |
| 储存缓冲液 | Supplied as a 0.22 μm filtered solution in 100mM Pro-AC, 20mM Arg, pH 5.0 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | -80℃储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。 |
| CAS编号和信息 | 356547-88-1 |
| 分子类型 | 抗体 |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
Belimumab (anti-TNFSF13B) (Ab170933) - SEC
The purity of Belimumab (anti-TNFSF13B) (Ab170933) is more than 95% verified by HPLC.
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab170933 | |
| 分析证书 | Ab170933 | |
| 分析证书 | Ab170933 | |
| 分析证书 | Ab170933 | |
| 分析证书 | Ab170933 |
¥183.92
| 1. Schneider P, MacKay F, Steiner V, Hofmann K, Bodmer JL, Holler N, Ambrose C, Lawton P, Bixler S, Acha-Orbea H et al.. (1999) BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth.. J Exp Med, 189 (11): (1747-56). [PMID:10359578] |
| 2. Shu, H B HB, Hu, W H WH and Johnson, H H.. (1999) TALL-1 is a novel member of the TNF family that is down-regulated by mitogens.. Journal of leukocyte biology, [PMID:10331498] |
| 3. Moore, P A PA and 21 more authors.. (1999) BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator.. Science (New York, N.Y.), (9): [PMID:10398604] |
| 4. Yu, G G and 16 more authors.. (2000) APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity.. Nature immunology, [PMID:10973284] |
| 5. Karpusas, Michael M and 7 more authors.. (2002) Crystal structure of extracellular human BAFF, a TNF family member that stimulates B lymphocytes.. Journal of molecular biology, (1): [PMID:11827482] |
| 6. Liu, Yingfang Y and 5 more authors.. (2002) Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands.. Cell, (8): [PMID:11853672] |
| 7. Gavin, Amanda L AL, Aït-Azzouzene, Djemel D, Ware, Carl F CF and Nemazee, David D.. (2003) DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF.. The Journal of biological chemistry, (3): [PMID:12867412] |
| 8. Dunham, A A and 125 more authors.. (2004) The DNA sequence and analysis of human chromosome 13.. Nature, (1): [PMID:15057823] |
| 9. Lahiri, Ayan A and 6 more authors.. (2012) The complexity of the BAFF TNF-family members: implications for autoimmunity.. Journal of autoimmunity, [PMID:22749832] |