首页
抗体
重组抗体
Recombinant TXNRD1 Antibody

Recombinant TXNRD1 Antibody

1篇引用文献

级别和纯度:

0.7 mg/mL

应用:

IF/ICC
IHC
WB

宿主种属: 兔(Rabbit)
种属反应性: 人(Human), 小鼠(Mouse)
亚型: Rabbit IgG
偶联: Unconjugated

有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货
Ab133101-10μl	10μl	现货
Ab133101-50μl	50μL	现货
Ab133101-100μl	100μL	期货
Ab133101-1ml	1ml	期货

查看相关系列

点击查看靶蛋白信息: TXNRD1

Accession#:Q16881 (1) Gene ID:7296 (1) TXNRD1 (1)

Skip to the end of the images gallery

Skip to the beginning of the images gallery

基本信息

产品名称	Recombinant TXNRD1 Antibody
别名	硫氧还蛋白还原酶1抗体 \| 重组TXNRD1抗体
英文别名	EC 1.8.1.9 \| Gene associated with retinoic and IFN-induced mortality 12 protein \| Gene associated with retinoic and interferon-induced mortality 12 protein \| GRIM-12 \| KM-102-derived reductase-like factor \| Thioredoxin reductase TR1 \| TR \| cytoplasmic ant
规格或纯度	ExactAb™, Validated, 重组, 0.7 mg/mL
宿主种属	兔(Rabbit)
特异性	TXNRD1
种属反应性	人(Human),小鼠(Mouse)
免疫原	Recombinant full length protein (Human).
阳性对照	WB: K562, Hep G2, Jurkat, LNCaP, NIH/3T3 and C6 cell lysates. IHC: Human lung cancer tissues. ICC/IF: HeLa cells.
偶联	Unconjugated

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Rabbit IgG
SDS-PAGE	150 kDa
纯化方法	Antigen affinity purified
物理外观	Liquid
储存缓冲液	50mM Tris-Glycine, 150mM NaCl, 40% Glycerol, 0.05% BSA, 0.01% Sodium azide, pH 7.4
防腐剂	0.01% Sodium aizde
浓度	0.7 mg/mL
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	4℃ 短期储存（1-2 周）。-20℃长期保存（24 个月）。收货后建议分装。避免冷冻/解冻循环。
分子类型	抗体

关联靶点（人）

TXNRD1 Tclin 硫氧还蛋白还原酶 1，细胞质(Thioredoxin reductase 1, cytoplasmic) (0 活性数据)

点击查看靶蛋白信息： TXNRD1

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

TXNRD1 Tclin Thioredoxin reductase 1 (99 活性数据)

点击查看靶蛋白信息： TXNRD1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Western Blot: Recombinant TXNRD1 Antibody (Ab133101)

Recombinant TXNRD1 Antibody (Ab133101) - Western Blot
All lanes: Recombinant TXNRD1 Antibody (Ab133101) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 71 kDa
Observed band size: 55, 61 kDa
Exposure time: 21.3 s

Western Blot: Recombinant TXNRD1 Antibody (Ab133101)

IF/ICC: Recombinant TXNRD1 Antibody (Ab133101)

Recombinant TXNRD1 Antibody (Ab133101) - IF/ICC
Immunocytochemistry analysis of TXNRD1 (green) in HeLa using Recombinant TXNRD1 Antibody (Ab133101), and cells were counterstained with DAPI (blue).

IHC: Recombinant TXNRD1 Antibody (Ab133101)

Recombinant TXNRD1 Antibody (Ab133101) - IHC
Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Recombinant TXNRD1 Antibody (Ab133101). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

应用

应用名称	稀释比例
WB	1/500-1/1000
IHC	1/50 - 1/100
IF/ICC	1/50-1/200

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到3个结果

批号(Lot Number)	证书类型	货号
ZJ25F0319599	分析证书	Ab133101
ZJ24F0303480	分析证书	Ab133101
ZJ24F0303479	分析证书	Ab133101

技术文档和文章

冷冻样本的免疫组织化学染色实验方案（IHC-Fr）

Categories: 实验方案（Protocols）

探索主题:

重组抗体单克隆抗体 IHC 免疫组化冷冻切片

免疫组织化学染色的抗原修复方案

Categories: 实验方案（Protocols）

探索主题:

重组抗体单克隆抗体 IHC 免疫组化抗原修复

免疫荧光染色实验步骤（甲醇通透法）

Categories: 实验方案（Protocols）

探索主题:

冷冻切片免疫荧光染色组织切片甲醇通透 IF

Immunofluorescence Staining Protocol (Methanol permeabilization)

Categories: 实验方案（Protocols）

探索主题:

Frozen section IF Immunofluorescence staining Tissue section Methanol permeability

Immunofluorescence Staining Protocol (Methanol permeabilization)

Categories: 实验方案（Protocols）

探索主题:

Frozen section IF Immunofluorescence staining Tissue section Methanol permeability

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站? 引用文献检索

引用文献

1. Watts KR, Ratnam J, Ang KH, Tenney K, Compton JE, McKerrow J, Crews P. (2010) Assessing the trypanocidal potential of natural and semi-synthetic diketopiperazines from two deep water marine-derived fungi.. Bioorg Med Chem, 18 (7): (2566-74). [PMID:20303767]
2. Tan L, Gurbani D, Weisberg EL, Jones DS, Rao S, Singer WD, Bernard FM, Mowafy S, Jenney A, Du G et al.. (2017) Studies of TAK1-centered polypharmacology with novel covalent TAK1 inhibitors.. Bioorg Med Chem, 25 (4): (1320-1328). [PMID:28038940]
3. Sharon Gauci,Andreas O Helbig,Monique Slijper,Jeroen Krijgsveld,Albert J R Heck,Shabaz Mohammed. (2009-05-06) Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.. Analytical chemistry, 81 ((11)): (4493-4501). [PMID:19413330]
4. Jovanović M, Zhukovsky D, Podolski-Renić A, Domračeva I, Žalubovskis R, Senćanski M, Glišić S, Sharoyko V, Tennikova T, Dar'in D, Pešić M, Krasavin M.. (2019) Novel electrophilic amides amenable by the Ugi reaction perturb thioredoxin system via thioredoxin reductase 1 (TrxR1) inhibition: Identification of DVD-445 as a new lead compound for anticancer therapy.. Eur J Med Chem, 181 (111580-111580). [PMID:31400708] [10.1016/j.ejmech.2019.111580]
5. Ai Y, Zhu B, Ren C, Kang F, Li J, Huang Z, Lai Y, Peng S, Ding K, Tian J, Zhang Y.. (2016) Discovery of New Monocarbonyl Ligustrazine-Curcumin Hybrids for Intervention of Drug-Sensitive and Drug-Resistant Lung Cancer.. J Med Chem, 59 (5): (1747-1760). [PMID:26891099] [10.1021/acs.jmedchem.5b01203]
6. Zhu P,Qian J,Xu Z,Meng C,Liu J,Shan W,Zhu W,Wang Y,Yang Y,Zhang W,Zhang Y,Ling Y. (2020) Piperlonguminine and Piperine Analogues as TrxR Inhibitors that Promote ROS and Autophagy and Regulate p38 and Akt/mTOR Signaling.. J Nat Prod, 83 (10.0): (3041-3049). [PMID:33026807] [10.1021/acs.jnatprod.0c00599]
7. Gasdaska, P Y PY, Gasdaska, J R JR, Cochran, S S and Powis, G G.. (1995) Cloning and sequencing of a human thioredoxin reductase.. FEBS letters, (2): [PMID:7589432]
8. Tamura, T T and Stadtman, T C TC.. (1996) A new selenoprotein from human lung adenocarcinoma cells: purification, properties, and thioredoxin reductase activity.. Proceedings of the National Academy of Sciences of the United States of America, (6): [PMID:8577704]
9. Gladyshev, V N VN, Jeang, K T KT and Stadtman, T C TC.. (1996) Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene.. Proceedings of the National Academy of Sciences of the United States of America, (11): [PMID:8650234]
10. Koishi, R R, Kawashima, I I, Yoshimura, C C, Sugawara, M M and Serizawa, N N.. (1997) Cloning and characterization of a novel oxidoreductase KDRF from a human bone marrow-derived stromal cell line KM-102.. The Journal of biological chemistry, (24): [PMID:8999974]
11. Hofmann, E R ER and 8 more authors.. (1998) Thioredoxin reductase mediates cell death effects of the combination of beta interferon and retinoic acid.. Molecular and cellular biology, [PMID:9774665]
12. Rundlöf, Anna-Klara AK, Janard, Magnus M, Miranda-Vizuete, Antonio A and Arnér, Elias S J ES.. (2004) Evidence for intriguingly complex transcription of human thioredoxin reductase 1.. Free radical biology & medicine, (1): [PMID:14980707]
13. Damdimopoulos, Anastasios E AE, Miranda-Vizuete, Antonio A, Treuter, Eckardt E, Gustafsson, Jan-Ake JA and Spyrou, Giannis G.. (2004) An alternative splicing variant of the selenoprotein thioredoxin reductase is a modulator of estrogen signaling.. The Journal of biological chemistry, (10): [PMID:15199063]
14. Rush, John J and 9 more authors.. (2005) Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.. Nature biotechnology, [PMID:15592455]
15. Scherer, Steven E SE and 216 more authors.. (2006) The finished DNA sequence of human chromosome 12.. Nature, (16): [PMID:16541075]
16. Wong, Joyce Jing Yi JJ, Pung, Yuh Fen YF, Sze, Newman Siu-Kwan NS and Chin, Keh-Chuang KC.. (2006) HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type I IFN-induced ISGylation of protein targets.. Proceedings of the National Academy of Sciences of the United States of America, (11): [PMID:16815975]
17. Fritz-Wolf, Karin K, Urig, Sabine S and Becker, Katja K.. (2007) The structure of human thioredoxin reductase 1 provides insights into C-terminal rearrangements during catalysis.. Journal of molecular biology, (29): [PMID:17512005]
18. Dammeyer, Pascal P and 5 more authors.. (2008) Induction of cell membrane protrusions by the N-terminal glutaredoxin domain of a rare splice variant of human thioredoxin reductase 1.. The Journal of biological chemistry, (1): [PMID:18042542]
19. Mayya, Viveka V and 7 more authors.. (2009) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.. Science signaling, (18): [PMID:19690332]
20. Bienvenut, Willy V WV and 6 more authors.. (2012) Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-α-acetylation features.. Molecular & cellular proteomics : MCP, [PMID:22223895]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

体积

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)

浓度 2 (C2)

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度

Recombinant TXNRD1 Antibody

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

技术文档和文章

相关产品

此产品的引用文献

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器