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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab131831-10μl |
10μl |
现货 ![]() |
| |
| Ab131831-50μl |
50μL |
现货 ![]() |
| |
| Ab131831-100μl |
100μL |
期货 ![]() |
| |
| Ab131831-1ml |
1ml |
期货 ![]() |
|
| 产品名称 | Recombinant TNF Receptor II Antibody |
|---|---|
| 别名 | 重组 TNF 受体 II 抗体 |
| 英文别名 | CD120b antibody | p75 antibody | p75 TNF receptor antibody | p75TNFR antibody | p80 TNF alpha receptor antibody | p80 TNF-alpha receptor antibody | Soluble TNFR1B variant 1 antibody | TBP-2 antibody | TBPII antibody | TNF R II antibody | TNF R2 antibody | |
| 规格或纯度 | ExactAb™, Validated, 重组, 0.5 mg/mL |
| 宿主种属 | 兔(Rabbit) |
| 特异性 | TNF Receptor II |
| 种属反应性 | 人(Human),大鼠(Rat),小鼠(Mouse) |
| 免疫原 | A synthetic peptide derived from human TNF Receptor II (AA 415-461) |
| 阳性对照 | WB: Jurkat, MCF7, HeLa, THP-1 and K562 cell lysates. |
| 偶联 | Unconjugated |
| 克隆类型 | 重组抗体 |
|---|---|
| Format | Whole IgG |
| 亚型 | Rabbit IgG |
| 轻链亚型 | kappa |
| SDS-PAGE | 150 kDa |
| 纯化方法 | Protein A purified |
| 物理外观 | Liquid |
| 储存缓冲液 | 10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4 |
| 防腐剂 | 0.02% Sodium aizde |
| 浓度 | 0.5 mg/mL |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 4℃ 短期储存(1-2 周)。-20℃长期保存(24 个月)。收货后建议分装。避免冷冻/解冻循环。 |
| 分子类型 | 抗体 |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
Recombinant TNF Receptor II Antibody (Ab131831) - Western Blot
All lanes: Recombinant TNF Receptor II Antibody (Ab131831) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 48 kDa
Observed band size: 68 kDa
Exposure time: 12.9 s
| 应用名称 | 稀释比例 |
|---|---|
| WB | 1/500-1/1000 |
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab131831 | |
| 分析证书 | Ab131831 |
| 1. Pennica, D D and 7 more authors.. (1992) Biochemical properties of the 75-kDa tumor necrosis factor receptor. Characterization of ligand binding, internalization, and receptor phosphorylation.. The Journal of biological chemistry, (15): [PMID:1328224] |
| 2. Dembic, Z Z and 7 more authors.. (1990) Two human TNF receptors have similar extracellular, but distinct intracellular, domain sequences.. Cytokine, [PMID:1966549] |
| 3. Engelmann, H H, Novick, D D and Wallach, D D.. (1990) Two tumor necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors.. The Journal of biological chemistry, (25): [PMID:2153136] |
| 4. Smith, C A CA and 8 more authors.. (1990) A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins.. Science (New York, N.Y.), (25): [PMID:2160731] |
| 5. Heller, R A RA and 5 more authors.. (1990) Complementary DNA cloning of a receptor for tumor necrosis factor and demonstration of a shed form of the receptor.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2166946] |
| 6. Kohno, T T and 8 more authors.. (1990) A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2172983] |
| 7. Loetscher, H H and 5 more authors.. (1990) Purification and partial amino acid sequence analysis of two distinct tumor necrosis factor receptors from HL60 cells.. The Journal of biological chemistry, (25): [PMID:2173696] |
| 8. Suzuki, J J and 5 more authors.. (1994) Purification of two types of TNF inhibitors in the urine of the patient with chronic glomerulonephritis.. Nephron, [PMID:8015639] |
| 9. Rothe, M M, Wong, S C SC, Henzel, W J WJ and Goeddel, D V DV.. (1994) A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor.. Cell, (26): [PMID:8069916] |
| 10. Beltinger, C P CP and 9 more authors.. (1996) Physical mapping and genomic structure of the human TNFR2 gene.. Genomics, (1): [PMID:8661109] |
| 11. Park, Y C YC, Burkitt, V V, Villa, A R AR, Tong, L L and Wu, H H.. (1999) Structural basis for self-association and receptor recognition of human TRAF2.. Nature, (8): [PMID:10206649] |
| 12. Tsuchiya, N N, Komata, T T, Matsushita, M M, Ohashi, J J and Tokunaga, K K.. (2000) New single nucleotide polymorphisms in the coding region of human TNFR2: association with systemic lupus erythematosus.. Genes and immunity, [PMID:11197692] |
| 13. Morita, C C and 10 more authors.. (2001) Association of tumor necrosis factor receptor type II polymorphism 196R with Systemic lupus erythematosus in the Japanese: molecular and functional analysis.. Arthritis and rheumatism, [PMID:11762942] |
| 14. Peral, Belén B, San Millán, José L JL, Castello, Roberto R, Moghetti, Paolo P and Escobar-Morreale, Héctor F HF.. (2002) Comment: the methionine 196 arginine polymorphism in exon 6 of the TNF receptor 2 gene (TNFRSF1B) is associated with the polycystic ovary syndrome and hyperandrogenism.. The Journal of clinical endocrinology and metabolism, [PMID:12161545] |
| 15. Pan, Shi S and 5 more authors.. (2002) Etk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: role in endothelial cell migration and angiogenesis.. Molecular and cellular biology, [PMID:12370298] |
| 16. Lainez, Begoña B and 6 more authors.. (2004) Identification and characterization of a novel spliced variant that encodes human soluble tumor necrosis factor receptor 2.. International immunology, [PMID:14688072] |
| 17. Gregory, S G SG and 178 more authors.. (2006) The DNA sequence and biological annotation of human chromosome 1.. Nature, (18): [PMID:16710414] |