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Recombinant Podoplanin Antibody

    应用:
  • WB
  • 宿主种属: 兔(Rabbit)
  • 种属反应性: 人(Human), 大鼠(Rat), 小鼠(Mouse)
  • 亚型: Rabbit IgG
  • 偶联: Unconjugated
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库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
Ab122503-10μl
10μl 现货 Stock Image
Ab122503-50μl
50μL 现货 Stock Image
Ab122503-100μl
100μL 期货 Stock Image
Ab122503-1ml
1ml 期货 Stock Image

基本信息

产品名称 Recombinant Podoplanin Antibody
别名 Podoplanin抗体 | 平足蛋白抗体 | 淋巴管内皮细胞蛋白抗体 | 重组足足蛋白抗体
英文别名 Aggrus antibody | Glycoprotein36 KD antibody | Glycoprotein 36 antibody | gp 36 antibody | GP 38 antibody | GP 40 antibody | gp36 antibody | GP38 antibody | GP40 antibody | HT1A 1 antibody | HT1A1 antibody | hT1alpha 1 antibody | hT1alpha 2 antibody | hT1
规格或纯度 ExactAb™, Validated, 重组, 0.93 mg/mL
宿主种属 兔(Rabbit)
特异性 Podoplanin
种属反应性 人(Human),大鼠(Rat),小鼠(Mouse)
免疫原 A synthetic peptide derived from human Podoplanin (AA 121-162)
阳性对照 WB: Mouse lung, U-2 OS and NIH/3T3 lysates.
偶联 Unconjugated

产品属性

克隆类型 重组抗体
Format Whole IgG
亚型 Rabbit IgG
轻链亚型 kappa
SDS-PAGE 150 kDa
纯化方法 Protein A purified
物理外观 Liquid
储存缓冲液 10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4
防腐剂 0.02% Sodium azide
浓度 0.93 mg/mL
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 4℃ 短期储存(1-2 周)。-20℃长期保存(24 个月)。收货后建议分装。避免冷冻/解冻循环。
分子类型 抗体

关联靶点(人)

PDPN Tbio 平足蛋白(Podoplanin) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

图片

Recombinant Podoplanin Antibody (Ab122503) - Western Blot
All lanes: Recombinant Podoplanin Antibody (Ab122503) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 17 kDa
Observed band size: 38 kDa
Exposure time: 60.0 s

Recombinant Podoplanin Antibody (Ab122503) - Western Blot
All lanes: Recombinant Podoplanin Antibody (Ab122503) at 1/1000 dilution
Samples: Lysates at 15 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 17 kDa
Observed band size: 37 kDa
Exposure time: 60.0 s

应用

应用名称 稀释比例
WB

1/500-1/1000

质检证书(CoA,COO,BSE/TSE 和分析图谱)

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找到2个结果

批号(Lot Number) 证书类型 货号
ZJ24F0505725 分析证书 Ab122503
ZJ24F0505724 分析证书 Ab122503

引用文献

1. Ma, T T, Yang, B B, Matthay, M A MA and Verkman, A S AS..  (1998)  Evidence against a role of mouse, rat, and two cloned human t1alpha isoforms as a water channel or a regulator of aquaporin-type water channels..  American journal of respiratory cell and molecular biology,  [PMID:9651190]
2. Zimmer, G G and 6 more authors..  (1999)  Cloning and characterization of gp36, a human mucin-type glycoprotein preferentially expressed in vascular endothelium..  The Biochemical journal,  (15): [PMID:10393083]
3. Kato, Yukinari Y and 6 more authors..  (2003)  Molecular identification of Aggrus/T1alpha as a platelet aggregation-inducing factor expressed in colorectal tumors..  The Journal of biological chemistry,  (19): [PMID:14522983]
4. Kerjaschki, Dontscho D and 13 more authors..  (2004)  Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates..  Journal of the American Society of Nephrology : JASN,  [PMID:14978162]
5. Kaneko, Mika M and 5 more authors..  (2004)  Functional sialylated O-glycan to platelet aggregation on Aggrus (T1alpha/Podoplanin) molecules expressed in Chinese hamster ovary cells..  The Journal of biological chemistry,  (10): [PMID:15231832]
6. Martín-Villar, Ester E and 6 more authors..  (2005)  Characterization of human PA2.26 antigen (T1alpha-2, podoplanin), a small membrane mucin induced in oral squamous cell carcinomas..  International journal of cancer,  (1): [PMID:15515019]
7. Otsuki, Tetsuji T and 24 more authors..  (2005)  Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries..  DNA research : an international journal for rapid publication of reports on genes and genomes,  [PMID:16303743]
8. Gregory, S G SG and 178 more authors..  (2006)  The DNA sequence and biological annotation of human chromosome 1..  Nature,  (18): [PMID:16710414]
9. Martín-Villar, Ester E and 5 more authors..  (2006)  Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition..  Journal of cell science,  (1): [PMID:17046996]
10. Kaneko, Mika Kato MK and 12 more authors..  (2007)  Functional glycosylation of human podoplanin: glycan structure of platelet aggregation-inducing factor..  FEBS letters,  (23): [PMID:17222411]
11. Suzuki-Inoue, Katsue K and 8 more authors..  (2007)  Involvement of the snake toxin receptor CLEC-2, in podoplanin-mediated platelet activation, by cancer cells..  The Journal of biological chemistry,  (7): [PMID:17616532]
12. Christou, Charita M CM and 9 more authors..  (2008)  Renal cells activate the platelet receptor CLEC-2 through podoplanin..  The Biochemical journal,  (1): [PMID:18215137]
13. Nakazawa, Youya Y and 7 more authors..  (2008)  Tetraspanin family member CD9 inhibits Aggrus/podoplanin-induced platelet aggregation and suppresses pulmonary metastasis..  Blood,  (1): [PMID:18541721]
14. Cueni, Leah N LN and Detmar, Michael M..  (2009)  Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions..  Experimental cell research,  (10): [PMID:19268462]
15. Martín-Villar, Ester E and 7 more authors..  (2010)  Podoplanin associates with CD44 to promote directional cell migration..  Molecular biology of the cell,  [PMID:20962267]
16. Fernández-Muñoz, Beatriz B and 6 more authors..  (2011)  The transmembrane domain of podoplanin is required for its association with lipid rafts and the induction of epithelial-mesenchymal transition..  The international journal of biochemistry & cell biology,  [PMID:21376833]
17. Tsuneki, Masayuki M and 9 more authors..  (2013)  Extracellular heat shock protein A9 is a novel interaction partner of podoplanin in oral squamous cell carcinoma cells..  Biochemical and biophysical research communications,  (26): [PMID:23541579]
18. Yurrita, Maria M MM and 5 more authors..  (2014)  Podoplanin is a substrate of presenilin-1/γ-secretase..  The international journal of biochemistry & cell biology,  [PMID:24275092]
19. Nagae, Masamichi M and 5 more authors..  (2014)  A platform of C-type lectin-like receptor CLEC-2 for binding O-glycosylated podoplanin and nonglycosylated rhodocytin..  Structure (London, England : 1993),  (2): [PMID:25458834]
20. Martín-Villar, E E and 6 more authors..  (2015)  Podoplanin mediates ECM degradation by squamous carcinoma cells through control of invadopodia stability..  Oncogene,  (20): [PMID:25486435]

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