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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab118002-10μl |
10μl |
现货 ![]() |
| |
| Ab118002-50μl |
50μL |
现货 ![]() |
| |
| Ab118002-100μl |
100μL |
现货 ![]() |
| |
| Ab118002-1ml |
1ml |
期货 ![]() |
|
| 产品名称 | NGF Mouse mAb |
|---|---|
| 别名 | 神经生长因子β抗体 | NGF小鼠单克隆抗体 | NGF小鼠单抗 |
| 英文别名 | Beta nerve growth factor precursor | beta-nerve growth factor | betaNGF | beta-NGF | HSAN5 | MGC161426 | nerve growth factor (beta polypeptide) | nerve growth factor, beta subunit | NGFB | NGFBMGC161428 | Beta nerve growth factor antibody | Beta NGF antib |
| 规格或纯度 | 无载体, ExactAb™, 无叠氮钠, 已验证, 高性能, 见COA |
| 宿主种属 | 小鼠(Mouse) |
| 特异性 | NGF |
| 种属反应性 | 人(Human),牛(Cow),猪(Pig) |
| 免疫原 | Recombinant NGF expressed in E.coli (AA 19-239) |
| 阳性对照 | WB: HeLa, Jurkat, A549 and HEK293 cell lysates. |
| 偶联 | Unconjugated |
| 克隆类型 | 单克隆抗体 |
|---|---|
| 克隆号 | C2 |
| Format | Whole IgG |
| 亚型 | Mouse IgG1 |
| 轻链亚型 | kappa |
| SDS-PAGE | 150 kDa |
| 纯化方法 | Protein A + Protein G purified |
| 物理外观 | Liquid |
| 储存缓冲液 | 10mM PBS, 50% Glycerol, 0.05% Proclin 300, pH7.4 |
| 防腐剂 | 0.05% Proclin 300 |
| 浓度 | 见COA |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 4°C 短期储存(4 周)。-20°C下长期保存(12个月)。收货后建议分装。避免冷冻/解冻循环。 |
| 分子类型 | 抗体 |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
NGF Mouse mAb (Ab118002) - Western Blot
All lanes: NGF Mouse mAb (Ab118002) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution
Predicted band size: 28 kDa
Observed band size: 31 kDa
Exposure time: 109.0 s
| 应用名称 | 稀释比例 |
|---|---|
| WB |
0.01-2 µg/mL
|
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab118002 | |
| 分析证书 | Ab118002 | |
| 分析证书 | Ab118002 |
| 1. Klein, R R, Jing, S Q SQ, Nanduri, V V, O'Rourke, E E and Barbacid, M M.. (1991) The trk proto-oncogene encodes a receptor for nerve growth factor.. Cell, (5): [PMID:1849459] |
| 2. Hallböök, F F, Ibáñez, C F CF and Persson, H H.. (1991) Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary.. Neuron, [PMID:2025430] |
| 3. Borsani, G G and 7 more authors.. (1990) cDNA sequence of human beta-NGF.. Nucleic acids research, (11): [PMID:2374737] |
| 4. Ullrich, A A, Gray, A A, Berman, C C, Coussens, L L and Dull, T J TJ.. (1983) Sequence homology of human and mouse beta-NGF subunit genes.. Cold Spring Harbor symposia on quantitative biology, [PMID:6327169] |
| 5. Ullrich, A A, Gray, A A, Berman, C C and Dull, T J TJ.. (1983) Human beta-nerve growth factor gene sequence highly homologous to that of mouse.. Nature, (30): [PMID:6688123] |
| 6. Tong, Y Y, Wang, H H and Chen, W W.. (1997) [Cloning and sequencing of the gene for premature beta nerve growth factor].. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, [PMID:10322959] |
| 7. Cargill, M M and 17 more authors.. (1999) Characterization of single-nucleotide polymorphisms in coding regions of human genes.. Nature genetics, [PMID:10391209] |
| 8. Culmsee, C C, Semkova, I I and Krieglstein, J J.. (1999) NGF mediates the neuroprotective effect of the beta2-adrenoceptor agonist clenbuterol in vitro and in vivo: evidence from an NGF-antisense study.. Neurochemistry international, [PMID:10403429] |
| 9. Wiesmann, C C, Ultsch, M H MH, Bass, S H SH and de Vos, A M AM.. (1999) Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor.. Nature, (9): [PMID:10490030] |
| 10. Semkova, I I and Krieglstein, J J.. (1999) Neuroprotection mediated via neurotrophic factors and induction of neurotrophic factors.. Brain research. Brain research reviews, [PMID:10525174] |
| 11. Puls, I I and 5 more authors.. (1999) [Clenbuterol in amyotrophic lateral sclerosis. No indication for a positive effect].. Der Nervenarzt, [PMID:10637819] |
| 12. Riaz, S S SS and Tomlinson, D R DR.. (1999) Clenbuterol stimulates neurotrophic support in streptozotocin-diabetic rats.. Diabetes, obesity & metabolism, [PMID:11221812] |
| 13. Einarsdottir, Elisabet E and 8 more authors.. (2004) A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception.. Human molecular genetics, (15): [PMID:14976160] |
| 14. He, Xiao-Lin XL and Garcia, K Christopher KC.. (2004) Structure of nerve growth factor complexed with the shared neurotrophin receptor p75.. Science (New York, N.Y.), (7): [PMID:15131306] |
| 15. Gregory, S G SG and 178 more authors.. (2006) The DNA sequence and biological annotation of human chromosome 1.. Nature, (18): [PMID:16710414] |
| 16. Wehrman, Tom T and 5 more authors.. (2007) Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors.. Neuron, (4): [PMID:17196528] |
| 17. Wijeyewickrema, Lakshmi C LC, Gardiner, Elizabeth E EE, Gladigau, Elsa L EL, Berndt, Michael C MC and Andrews, Robert K RK.. (2010) Nerve growth factor inhibits metalloproteinase-disintegrins and blocks ectodomain shedding of platelet glycoprotein VI.. The Journal of biological chemistry, (16): [PMID:20164177] |
| 18. Carvalho, Ofélia P OP and 8 more authors.. (2011) A novel NGF mutation clarifies the molecular mechanism and extends the phenotypic spectrum of the HSAN5 neuropathy.. Journal of medical genetics, [PMID:20978020] |
| 19. Davidson, G L G and 20 more authors.. (2012) Frequency of mutations in the genes associated with hereditary sensory and autonomic neuropathy in a UK cohort.. Journal of neurology, [PMID:22302274] |
| 20. Cao, Ziqin and 6 more authors.. (2020) Targeting nerve growth factor, a new option for treatment of osteoarthritis: a network meta-analysis of comparative efficacy and safety with traditional drugs.. Aging, (3): [PMID:33293475] |