Ki67 Mouse mAb

COA

级别和纯度:

见COA

应用:

宿主种属: 小鼠(Mouse)
种属反应性: 人(Human)
亚型: Mouse IgG1
克隆号: YN00996m
偶联: Unconjugated

有货

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货号 (SKU)	包装规格	是否现货
Ab112020-10μl	10μl	现货
Ab112020-50μl	50μL	现货
Ab112020-100μl	100μL	现货
Ab112020-1ml	1ml	期货

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点击查看靶蛋白信息: MKI67

Accession#: P46013 (4) Gene ID: 4288 (4) Ki67 (4) MKI67 (4)

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基本信息

产品名称	Ki67 Mouse mAb
别名	增殖标志物Ki67抗体 \| 增殖标志物Ki67单克隆抗体 \| 增殖标志物Ki67组化抗体 \| MKI67抗体 \| MKI67单克隆抗体 \| MKI67组化抗体
英文别名	Antigen identified by monoclonal antibody Ki 67 antibody \| Antigen identified by monoclonal antibody Ki-67 antibody \| Antigen KI-67 antibody \| Antigen KI67 antibody \| KI67_HUMAN antibody \| KIA antibody \| Marker of proliferation Ki-67 antibody \| MIB 1 anti
规格或纯度	无载体, ExactAb™, 无叠氮钠, 已验证, 见COA
生化机理	Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. Does not contribute to the internal structure of mitotic chromosomes (By similarity). May play a role in chromatin organization. It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed.
宿主种属	小鼠(Mouse)
特异性	Ki67
种属反应性	人(Human)
免疫原	Peptide
阳性对照	IHC: Human tonsil tissue.
偶联	Unconjugated

产品属性

克隆类型	单克隆抗体
克隆号	YN00996m
Format	Whole IgG
亚型	Mouse IgG
轻链亚型	kappa
SDS-PAGE	150 kDa
纯化方法	Protein G purified
物理外观	Liquid
储存缓冲液	10mM TBS, Glycerol, 0.1% Proclin 300, pH7.4
防腐剂	0.1% Proclin 300
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	-20℃长期保存（12 个月）。收货后建议分装。避免冷冻/解冻循环。
分子类型	抗体

关联靶点（人）

MKI67 Tbio 增殖标志蛋白 Ki-67(Proliferation marker protein Ki-67) (0 活性数据)

点击查看靶蛋白信息： MKI67

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

IHC: Ki67 Mouse mAb (Ab112020)

Ki67 Mouse mAb (Ab112020) - IHC
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue labelling Ki67 with Ki67 Mouse mAb (Ab112020) at 1/400 dilution. The section was incubated with Ki67 Mouse mAb (Ab112020) for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.

应用