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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab105938-10μl |
10μl |
期货 ![]() |
| |
| Ab105938-50μl |
50μL |
现货 ![]() |
| |
| Ab105938-100μl |
100μL |
现货 ![]() |
| |
| Ab105938-1ml |
1ml |
期货 ![]() |
|
| 产品名称 | GNB1 Antibody |
|---|---|
| 别名 | G蛋白/鸟苷酸结合蛋白抗体 | GNB1抗体 | GNB1多抗 | GNB1抗体 |
| 英文别名 | G protein beta subunit GI/GS/GT | guanine nucleotide binding protein (G protein), beta polypeptide 1 | guanine nucleotide-binding protein G | GBB1_HUMAN | Beta subunit signal transducing proteins GS/GI antibody | G protein beta 1 subunit antibody | GBB1 a |
| 规格或纯度 | ExactAb™, Validated, Carrier Free, 0.2 mg/mL |
| 宿主种属 | 兔(Rabbit) |
| 特异性 | GNB1 |
| 种属反应性 | 人(Human),大鼠(Rat),小鼠(Mouse) |
| 免疫原 | Fusion protein of human GNB1 (AA 100-340). |
| 阳性对照 | WB: Hep G2, A549, HEK293, Jurkat, HeLa, Raji, NIH/3T3 and C6 cell lysates. IHC: Human liver cancer tissue. |
| 偶联 | Unconjugated |
| 克隆类型 | 多克隆抗体 |
|---|---|
| Format | Whole IgG |
| 亚型 | Rabbit IgG |
| SDS-PAGE | 150 kDa |
| 纯化方法 | Protein A purified |
| 物理外观 | Liquid |
| 储存缓冲液 | 10mM PBS, 40% Glycerol, 0.05% Sodium azide, pH 7.4 |
| 防腐剂 | 0.05% Sodium azide |
| 浓度 | 0.2 mg/mL |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 4°C 短期储存(1-2 周)。-20°C下长期保存(24个月)。收货后建议分装。避免冷冻/解冻循环。 |
| 分子类型 | 抗体 |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
GNB1 Antibody (Ab105938) - Western Blot
All lanes: GNB1 Antibody (Ab105938) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 37 kDa
Observed band size: 35 kDa
Exposure time: 60.0 s
GNB1 Antibody (Ab105938) - IHC
Immunohistochemistry analysis of paraffin-embedded Human liver cancer using GNB1 Antibody (Ab105938). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
| 应用名称 | 稀释比例 |
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50 - 1/100 |
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab105938 | |
| 分析证书 | Ab105938 |
| 1. Sharon Gauci,Andreas O Helbig,Monique Slijper,Jeroen Krijgsveld,Albert J R Heck,Shabaz Mohammed. (2009-05-06) Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.. Analytical chemistry, 81 ((11)): (4493-4501). [PMID:19413330] |
| 2. Codina, J J, Stengel, D D, Woo, S L SL and Birnbaumer, L L.. (1986) Beta-subunits of the human liver Gs/Gi signal-transducing proteins and those of bovine retinal rod cell transducin are identical.. FEBS letters, (27): [PMID:3095147] |
| 3. Niu, Jiaxin J, Profirovic, Jasmina J, Pan, Haiyun H, Vaiskunaite, Rita R and Voyno-Yasenetskaya, Tatyana T.. (2003) G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: regulation of cell shape and reactive oxygen species production.. Circulation research, (31): [PMID:14512443] |
| 4. Gregory, S G SG and 178 more authors.. (2006) The DNA sequence and biological annotation of human chromosome 1.. Nature, (18): [PMID:16710414] |
| 5. Hill, Claire C, Goddard, Alan A, Ladds, Graham G and Davey, John J.. (2009) The cationic region of Rhes mediates its interactions with specific Gbeta subunits.. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, [PMID:19255495] |
| 6. Wang, Zhenglong Z and 9 more authors.. (2009) Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5.. The Journal of biological chemistry, (16): [PMID:19713215] |
| 7. Bienvenut, Willy V WV and 6 more authors.. (2012) Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-α-acetylation features.. Molecular & cellular proteomics : MCP, [PMID:22223895] |
| 8. Zhou, Houjiang H and 6 more authors.. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome.. Journal of proteome research, (4): [PMID:23186163] |
| 9. Yoda, Akinori A and 28 more authors.. (2015) Mutations in G protein β subunits promote transformation and kinase inhibitor resistance.. Nature medicine, [PMID:25485910] |
| 10. Petrovski, Slavé S and 46 more authors.. (2016) Germline De Novo Mutations in GNB1 Cause Severe Neurodevelopmental Disability, Hypotonia, and Seizures.. American journal of human genetics, (5): [PMID:27108799] |
| 11. Steinrücke, Sofia S and 7 more authors.. (2016) Novel GNB1 missense mutation in a patient with generalized dystonia, hypotonia, and intellectual disability.. Neurology. Genetics, [PMID:27668284] |
| 12. Lohmann, Katja K and 17 more authors.. (2017) Novel GNB1 mutations disrupt assembly and function of G protein heterotrimers and cause global developmental delay in humans.. Human molecular genetics, (15): [PMID:28087732] |
| 13. Thomas R Burkard,Melanie Planyavsky,Ines Kaupe,Florian P Breitwieser,Tilmann Bürckstümmer,Keiryn L Bennett,Giulio Superti-Furga,Jacques Colinge. (2011-01-29) Initial characterization of the human central proteome.. BMC systems biology, 5 (17-17). [PMID:21269460] |