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DTX3L Antibody

    应用:
  • WB
  • 宿主种属: 兔(Rabbit)
  • 种属反应性: 人(Human)
  • 亚型: Rabbit IgG
  • 偶联: Unconjugated
有货

库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
Ab100564-10μl
10μl 现货 Stock Image
Ab100564-50μl
50μL 现货 Stock Image
Ab100564-100μl
100μL 期货 Stock Image
Ab100564-1ml
1ml 期货 Stock Image

基本信息

产品名称 DTX3L Antibody
别名 DTX3L蛋白抗体 | DTX3L 抗体
英文别名 BBAP | RNF143 | B lymphoma and BAL associated protein antibody | B-lymphoma- and BAL-associated protein antibody | BBAP antibody | Deltex 3 like antibody | DTX 3L antibody | DTX3L antibody | DTX3L_HUMAN antibody | E3 ubiquitin-protein ligase DTX3L antibod
规格或纯度 ExactAb™, Validated, Carrier Free, 0.5 mg/mL
宿主种属 兔(Rabbit)
特异性 DTX3L
种属反应性 人(Human)
免疫原 Fusion protein of human DTX3L (AA 207-332).
阳性对照 WB: HT-29 and MCF7 cell lysates.
偶联 Unconjugated

产品属性

克隆类型 多克隆抗体
Format Whole IgG
亚型 Rabbit IgG
SDS-PAGE 150 kDa
纯化方法 Protein A purified
物理外观 Liquid
储存缓冲液 10mM PBS, 40% Glycerol, 0.05% Sodium azide, pH 7.4
防腐剂 0.05% Sodium azide
浓度 0.5 mg/mL
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 4°C 短期储存(1-2 周)。-20°C下长期保存(24个月)。收货后建议分装。避免冷冻/解冻循环。
分子类型 抗体

关联靶点(人)

DTX3L Tbio E3 泛素蛋白连接酶 DTX3L(E3 ubiquitin-protein ligase DTX3L) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

图片

DTX3L Antibody (Ab100564) - Western Blot
All lanes: DTX3L Antibody (Ab100564) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 84 kDa
Observed band size: 81 kDa
Exposure time: 10.0 s

DTX3L Antibody (Ab100564) - Western Blot
All lanes: DTX3L Antibody (Ab100564) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 84 kDa
Observed band size: 81 kDa
Exposure time: 96.2 s

应用

应用名称 稀释比例
WB

1/500-1/2000

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

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找到2个结果

批号(Lot Number) 证书类型 货号
ZJ24F0102413 分析证书 Ab100564
ZJ24F0102414 分析证书 Ab100564

技术文档和文章

免疫肽封闭实验
Immunopeptide blocking assay
Immunopeptide blocking assay
蛋白质印迹的一抗选择指南
Guidelines of Primary Antibodies for Western Blotting
Guidelines of Primary Antibodies for Western Blotting
高分子量蛋白质印迹法
Protocol of Western Blotting For High Molecular Weights
Protocol of Western Blotting For High Molecular Weights
Protocol of Western Blotting For High Molecular Weights
Protocol of Western Blotting For High Molecular Weights

引用文献

1. Takeyama, Kunihiko K and 7 more authors..  (2003)  The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity..  The Journal of biological chemistry,  (13): [PMID:12670957]
2. Juszczynski, Przemyslaw P and 5 more authors..  (2006)  BAL1 and BBAP are regulated by a gamma interferon-responsive bidirectional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate..  Molecular and cellular biology,  [PMID:16809771]
3. Sjöblom, Tobias T and 28 more authors..  (2006)  The consensus coding sequences of human breast and colorectal cancers..  Science (New York, N.Y.),  (13): [PMID:16959974]
4. Beausoleil, Sean A SA, Villén, Judit J, Gerber, Scott A SA, Rush, John J and Gygi, Steven P SP..  (2006)  A probability-based approach for high-throughput protein phosphorylation analysis and site localization..  Nature biotechnology,  [PMID:16964243]
5. Dephoure, Noah N and 6 more authors..  (2008)  A quantitative atlas of mitotic phosphorylation..  Proceedings of the National Academy of Sciences of the United States of America,  (5): [PMID:18669648]
6. Daub, Henrik H and 9 more authors..  (2008)  Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle..  Molecular cell,  (8): [PMID:18691976]
7. Yan, Qingsheng Q and 6 more authors..  (2009)  BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response..  Molecular cell,  (9): [PMID:19818714]
8. Obiero, Josiah J, Walker, John R JR and Dhe-Paganon, Sirano S..  (2012)  Fold of the conserved DTC domain in Deltex proteins..  Proteins,  [PMID:22411408]
9. Zhou, Houjiang H and 6 more authors..  (2013)  Toward a comprehensive characterization of a human cancer cell phosphoproteome..  Journal of proteome research,  (4): [PMID:23186163]
10. Yan, Qingsheng Q and 6 more authors..  (2013)  BAL1 and its partner E3 ligase, BBAP, link Poly(ADP-ribose) activation, ubiquitylation, and double-strand DNA repair independent of ATM, MDC1, and RNF8..  Molecular and cellular biology,  [PMID:23230272]
11. Holleman, Justine J and Marchese, Adriano A..  (2014)  The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein-coupled receptor CXCR4..  Molecular biology of the cell,  (15): [PMID:24790097]
12. Zhang, Yong Y and 18 more authors..  (2015)  PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection..  Nature immunology,  [PMID:26479788]
13. Yang, Chun-Song CS and 14 more authors..  (2017)  Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9..  Molecular cell,  (18): [PMID:28525742]

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