CREBBP Antibody

COA

级别和纯度:

已验证

ExactAb™

见COA

应用:

IF/ICC
IHC
WB

宿主种属: 兔(Rabbit)
种属反应性: 人(Human), 大鼠(Rat), 小鼠(Mouse), 牛(Cow), 狗(Dog), 猪(Pig), 鸡(Chicken)
亚型: Rabbit IgG
偶联: Unconjugated

有货

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货号 (SKU)	包装规格	是否现货
Ab097687-10μl	10μl	现货
Ab097687-50μl	50μL	现货
Ab097687-100μl	100μL	现货
Ab097687-1ml	1ml	期货

查看相关系列

点击查看靶蛋白信息: CREBBP

Accession#: Q92793 (1) CBP (1) CREBBP (1) Gene ID: 1387 (1)

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基本信息

产品名称	CREBBP Antibody
别名	CREB结合蛋白抗体
英文别名	KAT3A \| MKHK1 \| RSTS1 \| RSTS antibody \| RTS antibody \| Rubinstein Taybi syndrome antibody \| CBP \| RSTS \| CBP antibody \| CBP_HUMAN antibody \| CREB binding protein antibody \| CREB-binding protein antibody \| Crebbp antibody \| Cyclic AMP responsive enhancer b
规格或纯度	ExactAb™, 已验证, 见COA
生化机理	Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 coactivator. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300.
宿主种属	兔(Rabbit)
特异性	CREBBP
种属反应性	人(Human),大鼠(Rat),小鼠(Mouse),牛(Cow),狗(Dog),猪(Pig),鸡(Chicken)
免疫原	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CBP.
阳性对照	WB: HEK293 cell lysate. IHC: Human tonsil tissue. IF/ICC: A431 cells.
偶联	Unconjugated

产品属性

克隆类型	多克隆抗体
Format	Whole IgG
亚型	Rabbit IgG
SDS-PAGE	150 kDa
纯化方法	Immunogen affinity purified
物理外观	Liquid
储存缓冲液	0.42% Potassium phosphate, 0.87% Sodium chloride, 30% Glycerol, 0.01% Sodium azide, pH 7.3
防腐剂	0.01% Sodium azide
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	短期储存4°C（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。
分子类型	抗体

关联靶点（人）

CREBBP Tchem CREB结合蛋白(CREB-binding protein) (0 活性数据)

点击查看靶蛋白信息： CREBBP

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

CREBBP Tchem CREB-binding protein (1602 活性数据)

点击查看靶蛋白信息： CREBBP

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Western Blot: CREBBP Antibody (Ab097687)

CREBBP Antibody (Ab097687) - Western Blot
All lanes: CREBBP Antibody (Ab097687) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/10000 dilution
Predicted band size: 265 kDa
Observed band size: 100, 150, 270 kDa
Exposure time: 223.0 s

IHC: CREBBP Antibody (Ab097687)

CREBBP Antibody (Ab097687) - IHC
Immunohistochemical analysis of CBP staining in human tonsil formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with CREBBP Antibody (Ab097687) at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

IF/ICC: CREBBP Antibody (Ab097687)

CREBBP Antibody (Ab097687) - IF/ICC
Immunofluorescent analysis of CBP staining in A431 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with CREBBP Antibody (Ab097687) in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.