货号 (SKU)

包装规格

是否现货

价格

数量

Ab095284-10μg

10μg

现货

Ab095284-50μg

50μg

现货

Ab095284-100μg

100μg

现货

Ab095284-1mg

1mg

期货

基本信息

产品名称	CD74 Mouse mAb
别名	CD74单克隆抗体 \| CD74小鼠单克隆抗体 \| CD74小鼠单抗
英文别名	CD74 antigen (invariant polypeptide of major histocompatibility complex, classII antigen-associated) \| CD74 antigen \| CD74 molecule, major histocompatibility complex, class II invariant chain \| CD74 \| CLIP \| DHLAG \| DHLAGgamma chain of class II antigens \|
规格或纯度	无载体, ExactAb™, 无叠氮钠, 已验证, 见COA
宿主种属	小鼠(Mouse)
特异性	CD74
种属反应性	人(Human)
免疫原	SU-DHL-4 cells.
阳性对照	Flow: Human peripheral blood lymphocytes.
偶联	Unconjugated

产品属性

克隆类型	单克隆抗体
克隆号	LN2
Format	Whole IgG
亚型	Mouse IgG1
轻链亚型	kappa
SDS-PAGE	150 kDa
纯化方法	Protein G purified
物理外观	Liquid
储存缓冲液	10mM PBS, pH 7.2-7.4
防腐剂	No
浓度	见COA
储存温度	2-8°C储存
运输条件	冰袋运输
稳定性与储存	4°C 下运输。4°C 长期保存（12 个月）。收货后建议分装。
分子类型	抗体

关联靶点（人）

CD74 Tchem HLA II 类组织相容性抗原伽玛链(HLA class II histocompatibility antigen gamma chain) (0 活性数据)

点击查看靶蛋白信息： CD74

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

CD74 Tchem HLA-DR antigens-associated invariant chain (25 活性数据)

点击查看靶蛋白信息： CD74

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Flow Cytometry: CD74 Mouse mAb (Ab095284)

CD74 Mouse mAb (Ab095284) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD74 (red) with CD74 Mouse mAb (Ab095284) at 0.5 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: CD74 Mouse mAb (Ab095284)

CD74 Mouse mAb (Ab095284) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD74 (red) with CD74 Mouse mAb (Ab095284) conjugated with biotin at 2 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Isotype control, mouse IgG (Ab170221) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: CD74 Mouse mAb (Ab095284)

CD74 Mouse mAb (Ab095284) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD74 with CD74 Mouse mAb (Ab095284) conjugated with biotin (right panel) at 2 μg/mL for 1 hour at 4°C, compared with mouse IgG (Ab170221) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

应用

应用名称	稀释比例
Flow Cytometry	1μg/100w cells

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到3个结果

批号(Lot Number)	证书类型	货号
ZJ24F0404673	分析证书	Ab095284
ZJ24F0404674	分析证书	Ab095284
ZJ24F0404675	分析证书	Ab095284

技术文档和文章

利用甲醇通透法进行流式细胞术

Categories: 实验方案（Protocols）

探索主题:

流式细胞术流式抗体流式实验甲醇通透细胞分选细胞分型免疫研究细胞内抗原检测

Flow Cytometry Using Methanol Permeabilization

Categories: 实验方案（Protocols）

探索主题:

Flow Cytometry FlowCytometry methanolpermeabilization flowcytometryantibodies Cell Sorting Cell Typing Immunology Research Intracellular Antigen Detection

Flow Cytometry Using Methanol Permeabilization

Categories: 实验方案（Protocols）

探索主题:

Flow Cytometry FlowCytometry methanolpermeabilization flowcytometryantibodies Cell Sorting Cell Typing Immunology Research Intracellular Antigen Detection

可替换产品

引用文献

1. Sapra P, Stein R, Pickett J, Qu Z, Govindan SV, Cardillo TM, Hansen HJ, Horak ID, Griffiths GL, Goldenberg DM. (2005) Anti-CD74 antibody-doxorubicin conjugate, IMMU-110, in a human multiple myeloma xenograft and in monkeys.. Clin Cancer Res, 11 (14): (5257-64). [PMID:16033844]
2. Claesson L, Larhammar D, Rask L, Peterson PA. (1983) cDNA clone for the human invariant gamma chain of class II histocompatibility antigens and its implications for the protein structure.. Proc Natl Acad Sci USA, 80 (24): (7395-9). [PMID:6324166]
3. Kudo J, Chao LY, Narni F, Saunders GF. (1985) Structure of the human gene encoding the invariant gamma-chain of class II histocompatibility antigens.. Nucleic Acids Res, 13 (24): (8827-41). [PMID:3001652]
4. Leng L, Metz CN, Fang Y, Xu J, Donnelly S, Baugh J, Delohery T, Chen Y, Mitchell RA, Bucala R. (2003) MIF signal transduction initiated by binding to CD74.. J Exp Med, 197 (11): (1467-76). [PMID:12782713]
5. Alissa A Hare,Lin Leng,Sunilkumar Gandavadi,Xin Du,Zoe Cournia,Richard Bucala,William L Jorgensen. (2010-08-24) Optimization of N-benzyl-benzoxazol-2-ones as receptor antagonists of macrophage migration inhibitory factor (MIF).. Bioorganic & medicinal chemistry letters, 20 ((19)): (5811-5814). [PMID:20728358]
6. William L Jorgensen,Alexander Trofimov,Xin Du,Alissa A Hare,Lin Leng,Richard Bucala. (2011-07-02) Benzisothiazolones as modulators of macrophage migration inhibitory factor.. Bioorganic & medicinal chemistry letters, 21 ((15)): (4545-4549). [PMID:21719283]
7. Cournia Z, Leng L, Gandavadi S, Du X, Bucala R, Jorgensen WL.. (2009) Discovery of human macrophage migration inhibitory factor (MIF)-CD74 antagonists via virtual screening.. J Med Chem, 52 (2): (416-424). [PMID:19090668] [10.1021/jm801100v]
8. Jorgensen WL, Gandavadi S, Du X, Hare AA, Trofimov A, Leng L, Bucala R.. (2010) Receptor agonists of macrophage migration inhibitory factor.. Bioorg Med Chem Lett, 20 (23): (7033-7036). [PMID:20971005] [10.1016/j.bmcl.2010.09.118]
9. Riberdy, J M JM, Newcomb, J R JR, Surman, M J MJ, Barbosa, J A JA and Cresswell, P P.. (1992) HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides.. Nature, (3): [PMID:1448172]
10. O'Sullivan, D M DM, Larhammar, D D, Wilson, M C MC, Peterson, P A PA and Quaranta, V V.. (1986) Structure of the human Ia-associated invariant (gamma)-chain gene: identification of 5' sequences shared with major histocompatibility complex class II genes.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:3459184]
11. Strubin, M M, Mach, B B and Long, E O EO.. (1984) The complete sequence of the mRNA for the HLA-DR-associated invariant chain reveals a polypeptide with an unusual transmembrane polarity.. The EMBO journal, [PMID:6586420]
12. Ghosh, P P, Amaya, M M, Mellins, E E and Wiley, D C DC.. (1995) The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3.. Nature, (30): [PMID:7477400]
13. Jasanoff, A A, Wagner, G G and Wiley, D C DC.. (1998) Structure of a trimeric domain of the MHC class II-associated chaperonin and targeting protein Ii.. The EMBO journal, (1): [PMID:9843486]
14. Guncar, G G, Pungercic, G G, Klemencic, I I, Turk, V V and Turk, D D.. (1999) Crystal structure of MHC class II-associated p41 Ii fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S.. The EMBO journal, (15): [PMID:10022822]
15. Charest, Alain A and 6 more authors.. (2003) Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21).. Genes, chromosomes & cancer, [PMID:12661006]
16. Schmutz, Jeremy J and 75 more authors.. (2004) The DNA sequence and comparative analysis of human chromosome 5.. Nature, (16): [PMID:15372022]
17. Thomas R Burkard,Melanie Planyavsky,Ines Kaupe,Florian P Breitwieser,Tilmann Bürckstümmer,Keiryn L Bennett,Giulio Superti-Furga,Jacques Colinge. (2011-01-29) Initial characterization of the human central proteome.. BMC systems biology, 5 (17-17). [PMID:21269460]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

体积

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)

浓度 2 (C2)

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度

CD74 Mouse mAb

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

技术文档和文章

可替换产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

CD74 Mouse mAb

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

技术文档和文章

相关产品

可替换产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器