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Tilavonemab (anti-Tau) - Primary antibody, specific to MAPT, Human IgG1, INHIBITOR of Microtubule-associated protein tau inhibitor, INHIBITOR of Microtubule-associated protein tau inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab182805
Grouped product items
SKU Size
Availability
Price Qty
Ab182805-100μg
100μg
10
$49.90
Ab182805-1mg
1mg
4
$249.90
Ab182805-5mg
5mg
1
$649.90
Ab182805-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,029.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Tilavonemab (anti-Tau) - Primary antibody, specific to MAPT, Human IgG1, INHIBITOR of Microtubule-associated protein tau inhibitor
Synonyms AI413597 antibody | AW045860 antibody | DDPAC antibody | FLJ31424 antibody | FTDP 17 antibody | G protein beta1/gamma2 subunit interacting factor 1 antibody | MAPT antibody | MAPTL antibody | MGC134287 antibody | MGC138549 antibody | MGC156663 antibody |
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity MAPT
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Microtubule-associated protein tau inhibitor
Product Description

Tilavonemab (anti-Tau) is a humanised anti-tau antibody that binds amino acids 25-30 near the N-terminal end of the tau protein. Tilavonemab (anti-Tau) blocks the ability of human and mouse neurons to take up tau aggregates and reduces brain atrophy. Tilavonemab (anti-Tau) can be used in the study of Alzheimer's disease.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 145 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2096513-89-0

Associated Targets(Human)

MAPT Tclin Microtubule-associated protein tau (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
MAPT Tclin Microtubule-associated protein tau (95507 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAPT Tclin KEAP1/Microtubule-associated protein tau (1 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAPT Tclin KEAP1/Cullin-3/Microtubule-associated protein tau (13 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Tilavonemab (anti-Tau) (Ab182805) - ELISA
Immobilized pET22b-SYDX125-N-His-hu-flTau(2- 441aa) at 2.0 μg/mL can bind Tilavonemab (anti-Tau) (Ab182805) with the EC50 of 3.53 ng/mL.

Tilavonemab (anti-Tau) (Ab182805) - SEC
The purity of Tilavonemab (anti-Tau) (Ab182805) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0606943 Certificate of Analysis Jun 18, 2024 Ab182805
ZJ24F0606942 Certificate of Analysis Jun 18, 2024 Ab182805
ZJ24F0606941 Certificate of Analysis Jun 18, 2024 Ab182805

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