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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab182842-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$59.90
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Ab182842-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$269.90
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Ab182842-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$669.90
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Ab182842-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,069.90
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG4SP-Opti; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Semorinemab (anti-Tau) - Primary antibody, specific to MAPT, Human IgG4SP-Opti, INHIBITOR of Microtubule-associated protein tau inhibitor |
|---|---|
| Synonyms | AI413597 antibody | AW045860 antibody | DDPAC antibody | FLJ31424 antibody | FTDP 17 antibody | G protein beta1/gamma2 subunit interacting factor 1 antibody | MAPT antibody | MAPTL antibody | MGC134287 antibody | MGC138549 antibody | MGC156663 antibody | |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functi |
| Host species | Human |
| Specificity | MAPT |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Microtubule-associated protein tau inhibitor |
| Product Description |
Semorinemab (anti-Tau) is an anti-Tau humanized IgG4 monoclonal antibody, targets the N-terminal portion of the Tau protein (amino acid residues 6-23). Semorinemab (anti-Tau) binds with human Tau with a Kd value of 3.8 nM. Semorinemab (anti-Tau) can be used for the research of Alzheimer's Disease. |
| Isotype | Human IgG4SP-Opti |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145 kDa |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2159141-27-0 |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Semorinemab (anti-Tau) (Ab182842) - ELISA
Immobilized Recombinant N-His-hu-flTau(2-441aa) protein at 2.0 μg/mL can bind Semorinemab (anti-Tau) (Ab182842) with the EC
₅₀
of 4.58 ng/mL.
Semorinemab (anti-Tau) (Ab182842) - SEC
The purity of Semorinemab (anti-Tau) (Ab182842) is more than 95% verified by HPLC.