Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab182784-100μg
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100μg |
10
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$69.90
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Ab182784-1mg
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1mg |
4
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$339.90
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Ab182784-5mg
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5mg |
1
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$869.90
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Ab182784-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,479.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Gosuranemab (anti-Tau) - Primary antibody, specific to MAPT, Human IgG4SP, INHIBITOR of Microtubule-associated protein tau inhibitor |
|---|---|
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | MAPT |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Microtubule-associated protein tau inhibitor |
| Product Description |
Gosuranemab (anti-Tau) is a humanised IgG4 anti-tau monoclonal antibody. Gosuranemab (anti-Tau) binds to human N-terminal tau residues 15-22. Gosuranemab (anti-Tau) has the potential for the research of alzheimer’s disease (AD). |
| Isotype | Human IgG4SP |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.6 kDa (Light Chain) & 50.9 kDa (Heavy Chain), under reducing conditions; 195.4 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1788032-39-2 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Gosuranemab (anti-Tau) (Ab182784) - ELISA
Immobilized N-His-hu flTau (2-441 aa) tag at 2.0 μg/mL can bind Gosuranemab (anti-Tau) (Ab182784) with the EC₅₀ of 2.10 ng/mL.
Gosuranemab (anti-Tau) (Ab182784) - SEC
The purity of Gosuranemab (anti-Tau) (Ab182784) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | May 06, 2024 | Ab182784 | |
| Certificate of Analysis | May 06, 2024 | Ab182784 | |
| Certificate of Analysis | May 06, 2024 | Ab182784 |