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Tavolixizumab (anti-CD134) - Primary antibody, specific to TNFRSF4, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab182830
Grouped product items
SKU Size
Availability
Price Qty
Ab182830-100μg
100μg
10
$89.90
Ab182830-1mg
1mg
4
$449.90
Ab182830-5mg
5mg
1
$709.90
Ab182830-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,139.90

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Tavolixizumab (anti-CD134) - Primary antibody, specific to TNFRSF4, Human IgG1
Synonyms ACT 35 antibody | ACT35 antibody | ACT35 antigen antibody | ATC35 antigen antibody | CD 134 antibody | CD134 antibody | CD134 antigen antibody | IMD16 antibody | Lymphoid activation antigene ACT35 antibody | OX 40 antibody | OX40 antibody | OX40 antigen a
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity TNFRSF4
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Tavolixizumab (anti-CD134) is a human monoclonal antibody to TNFRSF4 (TNF receptor superfamily member 4) for use in cancer immunology research.
Purity
≥95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 26.7 kDa (Light Chain) & 51.3 kDa (Heavy Chain), under reducing conditions; 196.3 kDa, under non-reducing conditions.
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1635395-25-3

Associated Targets(Human)

TNFRSF4 Tchem Tumor necrosis factor receptor superfamily member 4 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Tavolixizumab (anti-CD134) (Ab182830) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling CD134 (red) with Tavolixizumab (anti-CD134) (Ab182830). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Tavolixizumab (anti-CD134) (Ab182830) - Flow Cytometry
OX40-NF-κB-Jurkat were stained with tavolimab (anti-CD134) (Ab182830) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, The EC₅₀ is 0.053 μg/mL.

Tavolixizumab (anti-CD134) (Ab182830) - SEC
The purity of Tavolixizumab (anti-CD134) (Ab182830) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0607199 Certificate of Analysis Jun 21, 2024 Ab182830
ZJ24F0607198 Certificate of Analysis Jun 21, 2024 Ab182830
ZJ24F0607197 Certificate of Analysis Jun 21, 2024 Ab182830

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