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Revdofilimab (anti-CD134) - Primary antibody, specific to TNFRSF4, Human IgG1

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab182874
Grouped product items
SKU Size
Availability
 Price Qty
Ab182874-100μg
100μg
10
$69.90
Ab182874-1mg
1mg
4
$349.90
Ab182874-5mg
5mg
1
$899.90
Ab182874-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,439.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: TNFRSF4
Accession#:P43489 (10) CD134 (11) Class A GPCR (4138) Gene ID:7293 (10) OX40 (11) TNFRSF4 (11)

Basic Description

Product Name Revdofilimab (anti-CD134) - Primary antibody, specific to TNFRSF4, Human IgG1
Synonyms ACT 35 antibody | ACT35 antibody | ACT35 antigen antibody | ATC35 antigen antibody | CD 134 antibody | CD134 antibody | CD134 antigen antibody | IMD16 antibody | Lymphoid activation antigene ACT35 antibody | OX 40 antibody | OX40 antibody | OX40 antigen a
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity TNFRSF4
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Revdofilimab (anti-CD134) is a human IgG1 agonist monoclonal antibody against OX40. Among them, OX40 is a member of the TNF receptor superfamily expressed on activated and memory T cell subsets and T regulatory cells.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 145.62 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2230138-89-1

Associated Targets(Human)

TNFRSF4 Tchem Tumor necrosis factor receptor superfamily member 4 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Revdofilimab (anti-CD134) (Ab182874) - Flow Cytometry
Flow Cytometry analysis of unstimulated (left) or 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated (right) Jurkat cells labelling CD134 (red) with Revdofilimab (anti-CD134) (Ab182874) at 0.1 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Revdofilimab (anti-CD134) (Ab182874) - Flow Cytometry
OX40-NF-κB-Jurkat were stained with Revdofilimab (anti-CD134) (Ab182874) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC₅₀=10 nM.

Revdofilimab (anti-CD134) (Ab182874) - SEC
The purity of Revdofilimab (anti-CD134) (Ab182874) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0607205 Certificate of Analysis Jun 21, 2024 Ab182874
ZJ24F0607204 Certificate of Analysis Jun 21, 2024 Ab182874
ZJ24F0607203 Certificate of Analysis Jun 21, 2024 Ab182874

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