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Figitumumab (anti-IGF1R) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IGF1R, >95%, high purity, Human IgG2SA, ANTAGONIST of Insulin-like growth factor I receptor antagonist, ANTAGONIST of Insulin-like growth factor I receptor antagonist

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG2SA
  • Conjugation: Unconjugated
In stock
Item Number
Ab170572
Grouped product items
SKU Size
Availability
Price Qty
Ab170572-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$79.90
Ab170572-1mg
1mg
5
$387.90
Ab170572-5mg
5mg
1
$957.90
Ab170572-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,497.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Figitumumab (anti-IGF1R) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IGF1R, >95%, high purity, Human IgG2SA, ANTAGONIST of Insulin-like growth factor I receptor antagonist
Synonyms EC 2.7.10.1 | IGF-I receptor | Insulin-like growth factor I receptor
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity IGF1R
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type ANTAGONIST
Mechanism of action ANTAGONIST of Insulin-like growth factor I receptor antagonist
Product Description

Figitumumab is a potent and fully human monoclonal anti–insulin-like growth factor 1 receptor (IGF1R) antibody. Figitumumab prevents IGF1 from binding to IGF1R.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG2SA
Light Chain Type kappa
SDS-PAGE 26.7 kDa (Light Chain) & 50.9 kDa (Heavy Chain), under reducing conditions; 170.3 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 943453-46-1

Associated Targets(Human)

IGF1R Tclin Insulin-like growth factor 1 receptor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
IGF1R Tclin Insulin-like growth factor I receptor (8605 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Figitumumab (anti-IGF1R) (Ab170572) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling IGF1R (red) with Figitumumab (anti-IGF1R) (Ab170572). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Figitumumab (anti-IGF1R) (Ab170572) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling IGF1R (red) with Figitumumab (anti-IGF1R) (Ab170572). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Figitumumab (anti-IGF1R) (Ab170572) - SEC
The purity of Figitumumab (anti-IGF1R) (Ab170572) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1101562 Certificate of Analysis Nov 08, 2023 Ab170572
ZJ23F1101563 Certificate of Analysis Nov 08, 2023 Ab170572

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