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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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D412014-100μg
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100μg |
10
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$99.90
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D412014-1mg
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1mg |
4
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$453.90
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D412014-5mg
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5mg |
1
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$1,889.90
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D412014-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$3,401.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Daratumumab (anti-CD38) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD38, >95%, high purity, Human IgG1, Antibody of CD38 |
|---|---|
| Synonyms | 2.4.99.20 | 2'-phospho-ADP-ribosyl cyclase | 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase | 2'-phospho-cyclic-ADP-ribose transferase | ADPRC 1 | ADP-ribosyl cyclase 1 | cADPr hydrolase 1 | Cyclic ADP-ribose hydrolase 1 | EC 3.2. |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CD38 |
| Application | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | Antibody of CD38 |
| Product Description |
Daratumumab (anti-CD38) is a recombinant monoclonal antibody to CD38. Daratumumab is an investigational anti-cancer drug which is indicated for the treatment of adult patients with multiple myeloma. |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG1 |
| Light Chain Type | kappa |
| SDS-PAGE | 24.5 kDa (Light Chain) & 50.3 kDa (Heavy Chain), under reducing conditions; 175.9 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 945721-28-8 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Daratumumab (anti-CD38) (D412014) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD38 (red) with Daratumumab (anti-CD38) (D412014). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Daratumumab (anti-CD38) (D412014) - SEC
The purity of Daratumumab (anti-CD38) (D412014) is more than 95% verified by HPLC.
Daratumumab (anti-CD38) (D412014) - ELISA
Immobilized human-CD38-ECD-Nhis at 2 μg/mL can bind Daratumumab (anti-CD38) (D412014) with the EC50 of 30.71 ng/mL.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 08, 2024 | D412014 | |
| Certificate of Analysis | Apr 08, 2024 | D412014 | |
| Certificate of Analysis | Apr 08, 2024 | D412014 |
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