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Daratumumab (anti-CD38) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD38, >95%, high purity, Human IgG1, Antibody of CD38, Antibody of CD38

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse,Rhesus monkey
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
D412014
Grouped product items
SKU Size
Availability
Price Qty
D412014-100μg
100μg
10
$99.90
D412014-1mg
1mg
4
$453.90
D412014-5mg
5mg
1
$1,889.90
D412014-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,401.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Daratumumab (anti-CD38) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD38, >95%, high purity, Human IgG1, Antibody of CD38
Synonyms 2.4.99.20 | 2'-phospho-ADP-ribosyl cyclase | 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase | 2'-phospho-cyclic-ADP-ribose transferase | ADPRC 1 | ADP-ribosyl cyclase 1 | cADPr hydrolase 1 | Cyclic ADP-ribose hydrolase 1 | EC 3.2.
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD38
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action Antibody of CD38
Product Description

Daratumumab (anti-CD38) is a recombinant monoclonal antibody to CD38. Daratumumab is an investigational anti-cancer drug which is indicated for the treatment of adult patients with multiple myeloma.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg 

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 24.5 kDa (Light Chain) & 50.3 kDa (Heavy Chain), under reducing conditions; 175.9 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 945721-28-8

Associated Targets(Human)

CD38 Tclin ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Daratumumab (anti-CD38) (D412014) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD38 (red) with Daratumumab (anti-CD38) (D412014). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Daratumumab (anti-CD38) (D412014) - SEC
The purity of Daratumumab (anti-CD38) (D412014) is more than 95% verified by HPLC.

Daratumumab (anti-CD38) (D412014) - ELISA
Immobilized human-CD38-ECD-Nhis at 2 μg/mL can bind Daratumumab (anti-CD38) (D412014) with the EC50 of 30.71 ng/mL.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404209 Certificate of Analysis Apr 08, 2024 D412014
ZJ24F0404210 Certificate of Analysis Apr 08, 2024 D412014
ZJ24F0404211 Certificate of Analysis Apr 08, 2024 D412014

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