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Mezagitamab (anti-CD38) - Primary antibody, specific to CD38, >95%, high purity, Human IgG1, Antibody of CD38, Antibody of CD38

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse,Rhesus monkey
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab175597
Grouped product items
SKU Size
Availability
 Price Qty
Ab175597-100μg
100μg
10
$59.90
Ab175597-1mg
1mg
4
$279.90
Ab175597-5mg
5mg
1
$739.90
Ab175597-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,189.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: CD38
Accession#:P28907 (14) Apoptosis (4276) CD38 (21) CD38 Antibody (3) Gene ID:952 (14)

Basic Description

Product Name Mezagitamab (anti-CD38) - Primary antibody, specific to CD38, >95%, high purity, Human IgG1, Antibody of CD38
Synonyms Acute lymphoblastic leukemia cells antigen CD38 antibody | ADP ribosyl cyclase 1 antibody | ADP ribosyl cyclase antibody | ADP ribosyl cyclase/cyclic ADP-ribose hydrolase antibody | ADP-ribosyl cyclase 1 antibody | ADPRC 1 antibody | ADPRC1 antibody | cAD
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD38
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type BINDING AGENT
Mechanism of action Antibody of CD38
Product Description

Mezagitamab (anti-CD38) is a IgG1λ anti-CD38 monoclonal antibody. Mezagitamab (anti-CD38) depletes tumor cells expressing CD38 through antibody and complement dependent cytotoxicity. Mezagitamab (anti-CD38) has potential application in relapsed/refractory multiple myeloma (RRMM) and idiopathic thrombocytopenic purpura (ITP).

Product Properties

Isotype Human IgG1
Light Chain Type lambda
SDS-PAGE 28.1 kDa (Light Chain) & 51.6 kDa (Heavy Chain), under reducing conditions; 182.1 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2227490-52-8

Associated Targets(Human)

CD38 Tclin ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Mezagitamab (anti-CD38) (Ab175597) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling DPP4 with Mezagitamab (anti-CD38) (Ab175597) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Mezagitamab (anti-CD38) (Ab175597) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling DPP4 (red) with Mezagitamab (anti-CD38) (Ab175597) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

Mezagitamab (anti-CD38) (Ab175597) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD38 (red) with Mezagitamab (anti-CD38) (Ab175597). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Mezagitamab (anti-CD38) (Ab175597) - SEC
The purity of Mezagitamab (anti-CD38) (Ab175597) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303100 Certificate of Analysis Mar 08, 2024 Ab175597
ZJ24F0303101 Certificate of Analysis Mar 08, 2024 Ab175597
ZJ24F0303102 Certificate of Analysis Mar 08, 2024 Ab175597

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