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PF-06342674 (anti-IL-7Ra) - Primary antibody, specific to IL7R, >95%, high purity, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab176218
Grouped product items
SKU Size
Availability
Price Qty
Ab176218-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$129.90
Ab176218-1mg
1mg
5
$649.90
Ab176218-5mg
5mg
1
$1,629.90
Ab176218-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,609.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name PF-06342674 (anti-IL-7Ra) - Primary antibody, specific to IL7R, >95%, high purity, Human IgG1
Synonyms CDw127 | IL-7 receptor subunit alpha | IL-7R subunit alpha | IL-7RA | IL-7R-alpha
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity IL7R
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

PF-06342674 (anti-IL-7Ra) is a monoclonal antibody against human IL-7Rα with therapeutic benefit against T-ALL (T-cell acute lymphoblastic leukemia).
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type lambda
SDS-PAGE 28.0 kDa (Light Chain) & 49.5 kDa (Heavy Chain), under reducing conditions; 176.3 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

IL7R Tbio Interleukin-7 receptor subunit alpha (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

PF-06342674 (anti-IL-7Ra) (Ab176218) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling IL-7Ra with PF-06342674 (anti-IL-7Ra) (Ab176218) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

PF-06342674 (anti-IL-7Ra) (Ab176218) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling IL-7Ra (red) with PF-06342674 (anti-IL-7Ra) (Ab176218) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

PF-06342674 (anti-IL-7Ra) (Ab176218) - Flow Cytometry
Flow Cytometry analysis of Hela cells labelling IL-7Ra (red) with PF-06342674 (anti-IL-7Ra) (Ab176218). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

PF-06342674 (anti-IL-7Ra) (Ab176218) - SEC
The purity of PF-06342674 (anti-IL-7Ra) (Ab176218) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1201942 Certificate of Analysis Dec 06, 2023 Ab176218
ZJ23F1201943 Certificate of Analysis Dec 06, 2023 Ab176218

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