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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab170617-100μg
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100μg |
2
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$89.90
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Ab170617-1mg
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1mg |
4
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$417.90
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Ab170617-5mg
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5mg |
1
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$867.90
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Ab170617-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,407.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; VHH; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Envafolimab (anti-PD-L1) - Primary antibody, for ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt various applications, specific to CD274, >95%, high purity, VHH, BINDING AGENT of Programmed cell death 1 ligand 1 binding agent |
|---|---|
| Synonyms | B7 H1 antibody | B7 homolog 1 antibody | B7-H1 antibody | B7H antibody | B7H1 antibody | CD 274 antibody | CD-274 antibody | CD274 antibody | CD274 antigen antibody | CD274 molecule antibody | MGC142294 antibody | MGC142296 antibody | OTTHUMP00000021029 a |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CD274 |
| Application | ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | BINDING AGENT |
| Mechanism of action | BINDING AGENT of Programmed cell death 1 ligand 1 binding agent |
| Product Description |
Envafolimab is a humanized anti- PD-L1 antibody. Envafolimab blocks interaction between PD-L1 and PD-1 with an IC50 value of 5.25 nM. Envafolimab has the potential for the research of solid tumors.
Purity >95% (SDS-PAGE&SEC) Endotoxin Level < 1.0EU/mg |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | VHH |
| SDS-PAGE | 80 kDa |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2102192-68-5 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Envafolimab (anti-PD-L1) (Ab170617) - Flow Cytometry
Flow Cytometry analysis of MDA-MB-231 cells labelling PD-L1 (red) with Envafolimab (anti-PD-L1) (Ab170617). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Envafolimab (anti-PD-L1) (Ab170617) - SEC
The purity of Envafolimab (anti-PD-L1) (Ab170617) is more than 95% verified by HPLC.
Envafolimab (anti-PD-L1) (Ab170617) - ELISA
Immobilized PD-L1-His at 2 μg/mL can bind Envafolimab (anti-PD-L1) (Ab170617) with the EC₅₀ of 3.57 ng/mL.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 26, 2024 | Ab170617 | |
| Certificate of Analysis | Apr 26, 2024 | Ab170617 | |
| Certificate of Analysis | Apr 26, 2024 | Ab170617 | |
| Certificate of Analysis | Sep 11, 2023 | Ab170617 | |
| Certificate of Analysis | Sep 11, 2023 | Ab170617 |
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