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Envafolimab (anti-PD-L1) - Primary antibody, for ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt various applications, specific to CD274, >95%, high purity, VHH, BINDING AGENT of Programmed cell death 1 ligand 1 binding agent, BINDING AGENT of Programmed cell death 1 ligand 1 binding agent

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: VHH
  • Conjugation: Unconjugated
In stock
Item Number
Ab170617
Grouped product items
SKU Size
Availability
Price Qty
Ab170617-100μg
100μg
2
$89.90
Ab170617-1mg
1mg
4
$417.90
Ab170617-5mg
5mg
1
$867.90
Ab170617-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,407.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; VHH; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Envafolimab (anti-PD-L1) - Primary antibody, for ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt various applications, specific to CD274, >95%, high purity, VHH, BINDING AGENT of Programmed cell death 1 ligand 1 binding agent
Synonyms B7 H1 antibody | B7 homolog 1 antibody | B7-H1 antibody | B7H antibody | B7H1 antibody | CD 274 antibody | CD-274 antibody | CD274 antibody | CD274 antigen antibody | CD274 molecule antibody | MGC142294 antibody | MGC142296 antibody | OTTHUMP00000021029 a
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD274
Application ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type BINDING AGENT
Mechanism of action BINDING AGENT of Programmed cell death 1 ligand 1 binding agent
Product Description

Envafolimab is a humanized anti- PD-L1 antibody. Envafolimab blocks interaction between PD-L1 and PD-1 with an IC50 value of 5.25 nM. Envafolimab has the potential for the research of solid tumors.

 

Purity

>95% (SDS-PAGE&SEC)

Endotoxin Level

< 1.0EU/mg 


Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype VHH
SDS-PAGE 80 kDa
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2102192-68-5

Associated Targets(Human)

CD274 Tclin Programmed cell death 1 ligand 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Envafolimab (anti-PD-L1) (Ab170617) - Flow Cytometry
Flow Cytometry analysis of MDA-MB-231 cells labelling PD-L1 (red) with Envafolimab (anti-PD-L1) (Ab170617). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Envafolimab (anti-PD-L1) (Ab170617) - SEC
The purity of Envafolimab (anti-PD-L1) (Ab170617) is more than 95% verified by HPLC.

Envafolimab (anti-PD-L1) (Ab170617) - ELISA
Immobilized PD-L1-His at 2 μg/mL can bind Envafolimab (anti-PD-L1) (Ab170617) with the EC₅₀ of 3.57 ng/mL.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot Number Certificate Type Date Item
ZJ24F0404941 Certificate of Analysis Apr 26, 2024 Ab170617
ZJ24F0404940 Certificate of Analysis Apr 26, 2024 Ab170617
ZJ24F0404942 Certificate of Analysis Apr 26, 2024 Ab170617
ZJ23F0900989 Certificate of Analysis Sep 11, 2023 Ab170617
ZJ23F0900988 Certificate of Analysis Sep 11, 2023 Ab170617

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