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Barzolvolimab (anti-c-Kit) - Primary antibody, specific to KIT, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab182977
Grouped product items
SKU Size
Availability
Price Qty
Ab182977-100μg
100μg
10
$239.90
Ab182977-1mg
1mg
4
$499.90
Ab182977-5mg
5mg
1
$889.90
Ab182977-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,429.90

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Barzolvolimab (anti-c-Kit) - Primary antibody, specific to KIT, Human IgG1
Synonyms C Kit antibody | c-Kit antibody | c-Kit Ligand antibody | CD117 antibody | Kit antibody | Kit Ligand antibody | KIT oncogene antibody | KIT proto oncogene receptor tyrosine kinase antibody | KIT_HUMAN antibody | Mast cell growth factor receptor antibody |
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity KIT
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Barzolvolimab (anti-c-Kit) is a humanized anti-KIT IgG1 monoclonal antibody. Barzolvolimab (anti-c-Kit) specificity and potently inhibits KIT activation by SCF. Barzolvolimab (anti-c-Kit) can reduce skin mast cells and disease activity in chronic inducible urticaria.

Purity

≥95% (SDS-PAGE&SEC)

Endotoxin Level

≤1.0EU/mg


Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 144.8 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2438203-51-9

Associated Targets(Human)

KIT Tclin Mast/stem cell growth factor receptor Kit (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
KIT Tclin Stem cell growth factor receptor (10667 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KIT Tclin VEGF-receptor 2 and stem cell growth factor receptor (KDR and KIT) (10 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KIT Tclin VHL/KIT (4 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Barzolvolimab (anti-c-Kit) (Ab182977) - ELISA
Immobilized Human SCFR/c-Kit /CD117 His Tag at 2.0 μg/mL can bind Barzolvolimab (anti-c-Kit) (Ab182977) with the EC ₅₀ of 38.74 ng/mL.

Barzolvolimab (anti-c-Kit) (Ab182977) - SEC
The purity of Barzolvolimab (anti-c-Kit) (Ab182977) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0607469 Certificate of Analysis Jun 28, 2024 Ab182977
ZJ24F0607468 Certificate of Analysis Jun 28, 2024 Ab182977
ZJ24F0607467 Certificate of Analysis Jun 28, 2024 Ab182977

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