Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Ab182977-100μg
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100μg |
10
|
$239.90
|
|
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Ab182977-1mg
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1mg |
4
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$499.90
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|
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Ab182977-5mg
|
5mg |
1
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$889.90
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|
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Ab182977-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,429.90
|
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Barzolvolimab (anti-c-Kit) - Primary antibody, specific to KIT, Human IgG1 |
|---|---|
| Synonyms | C Kit antibody | c-Kit antibody | c-Kit Ligand antibody | CD117 antibody | Kit antibody | Kit Ligand antibody | KIT oncogene antibody | KIT proto oncogene receptor tyrosine kinase antibody | KIT_HUMAN antibody | Mast cell growth factor receptor antibody | |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | KIT |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Barzolvolimab (anti-c-Kit) is a humanized anti-KIT IgG1 monoclonal antibody. Barzolvolimab (anti-c-Kit) specificity and potently inhibits KIT activation by SCF. Barzolvolimab (anti-c-Kit) can reduce skin mast cells and disease activity in chronic inducible urticaria. Purity ≥95% (SDS-PAGE&SEC) Endotoxin Level ≤1.0EU/mg |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 144.8 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2438203-51-9 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Barzolvolimab (anti-c-Kit) (Ab182977) - ELISA
Immobilized Human SCFR/c-Kit /CD117 His Tag at 2.0 μg/mL can bind Barzolvolimab (anti-c-Kit) (Ab182977) with the EC
₅₀
of 38.74 ng/mL.
Barzolvolimab (anti-c-Kit) (Ab182977) - SEC
The purity of Barzolvolimab (anti-c-Kit) (Ab182977) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jun 28, 2024 | Ab182977 | |
| Certificate of Analysis | Jun 28, 2024 | Ab182977 | |
| Certificate of Analysis | Jun 28, 2024 | Ab182977 |
Starting at $69.90
Starting at $69.90
Starting at $59.90
Starting at $36.90