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Anifrolumab (anti-IFNAR1) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IFNAR1, >95%, high purity, Human IgG1, Antibody of interferon α/β receptor 1, Antibody of interferon α/β receptor 1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab170489
Grouped product items
SKU Size
Availability
Price Qty
Ab170489-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$159.90
Ab170489-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$761.90
Ab170489-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,541.90
Ab170489-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,424.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Anifrolumab (anti-IFNAR1) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IFNAR1, >95%, high purity, Human IgG1, Antibody of interferon α/β receptor 1
Synonyms Anifrolumab | Alpha type antiviral protein antibody | Antiviral protein, alpha-type antibody | Antiviral protein, beta-type antibody | AVP antibody | Beta type antiviral protein antibody | CRF2-1 antibody | Cytokine receptor class-II member 1 antibody | C
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity IFNAR1
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type ANTAGONIST
Mechanism of action Antibody of interferon α/β receptor 1
Product Description

Anifrolumab (anti-IFNAR1) is a type I interferon (IFN) receptor antagonist, a recombinant monoclonal antibody. Anifrolumab blocks the activity of type I interferon. Anifrolumab can be used in systemic lupus erythematosus (SLE) research.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 27.3 kDa (Light Chain) & 53.4 kDa (Heavy Chain), under reducing conditions; 180.0 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1326232-46-5

Associated Targets(Human)

IFNAR1 Tclin Interferon alpha/beta receptor 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
IFNAR1 Tclin Interferon-alpha/beta receptor alpha chain (50 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Anifrolumab (anti-IFNAR1) (Ab170489) - SEC
The purity of Anifrolumab (anti-IFNAR1) (Ab170489) is more than 95% verified by HPLC.

Anifrolumab (anti-IFNAR1) (Ab170489) - ELISA
Immobilized Human IFNAR1, Fc at 2 μg/mL can bind Anifrolumab (anti-IFNAR1) (Ab170489) with the EC₅₀ of 14.7 ng/mL.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F0901153 Certificate of Analysis Sep 28, 2023 Ab170489
ZJ23F0901152 Certificate of Analysis Sep 28, 2023 Ab170489

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