Grouped product items

SKU

Size

Availability

Price

Qty

A412002-100μg

100μg

$39.90

A412002-1mg

1mg

$159.90

A412002-5mg

5mg

$664.90

A412002-10mg

10mg

Available within 8-12 weeks(?)

$1,196.90

Basic Description

Product Name	Adalimumab (anti-TNF-alpha) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to TNFSF2/TNFa, >95% (SDS-PAGE&SEC), high purity, Human IgG1, INHIBITOR of TNF-alpha inhibitor
Synonyms	dl-N-Acetylhomocysteinethiolactone \| ONO5046;LY544349;EI546 \| SIVELESTAT [INN] \| SIVELESTAT [MART.] \| 2,2-Dimethyl-propionic acid 4-[2-(carboxymethyl-carbamoyl)-phenylsulfamoyl]-phenyl ester \| P,.ALPHA.,.ALPHA.-TRIMETHYLBENZYL ALCOHOL [FHFI] \| J-005486 \|
Specifications & Purity	Carrier Free, Recombinant, ExactAb™, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species	Human
Specificity	TNFSF2/TNFa
Application	ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation	Unconjugated
Grade	Animal Free, Azide Free, Carrier Free, ExactAb™, Recombinant, Validated
Action Type	INHIBITOR
Mechanism of action	INHIBITOR of TNF-alpha inhibitor
Product Description	Adalimumab (anti-TNF-α) is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α). Purity>95% (SDS-PAGE&SEC) Endotoxin Level< 0.01EU/μg

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Benzene and substituted derivatives
    - Subclass Benzoic acids and derivatives
      - Level5 Benzamides
        Level6 Hippuric acids and derivatives
        Level7 Hippuric acids

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Benzene and substituted derivatives
Subclass	Benzoic acids and derivatives
Intermediate Tree Nodes	Benzamides - Hippuric acids and derivatives
Direct Parent	Hippuric acids
Alternative Parents	N-acyl-alpha amino acids Benzenesulfonamides Sulfanilides Phenol esters Benzenesulfonyl compounds Phenoxy compounds Benzoyl derivatives Organosulfonamides Dicarboxylic acids and derivatives Vinylogous amides Aminosulfonyl compounds Carboxylic acid esters Secondary carboxylic acid amides Carboxylic acids Organopnictogen compounds Hydrocarbon derivatives Carbonyl compounds Organic oxides Organonitrogen compounds
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Hippuric acid - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Alpha-amino acid or derivatives - Benzenesulfonamide - Phenol ester - Sulfanilide - Benzenesulfonyl group - Phenoxy compound - Benzoyl - Dicarboxylic acid or derivatives - Organosulfonic acid amide - Vinylogous amide - Aminosulfonyl compound - Sulfonyl - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Carboxylic acid ester - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid - Carboxylic acid derivative - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organosulfur compound - Organic oxygen compound - Organopnictogen compound - Carbonyl group - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as hippuric acids. These are compounds containing hippuric acid, which consists of a of a benzoyl group linked to the N-terminal of a glycine.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Product Properties

Antibody Type	Primary antibody
Clonality	Recombinant
Isotype	Human IgG1
Light Chain Type	kappa
SDS-PAGE	145.5 kDa
Purification Method	Protein A purified
Purity	>95% (SDS-PAGE&SEC)
Source	CHO supernatant
Shape	Liquid
Concentration	See COA
Storage Temp	Store at -80°C,Avoid repeated freezing and thawing
Shipped In	Ice chest + Ice pads
Stability And Storage	Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS	331731-18-1

Associated Targets(Human)

ELANE Tclin Neutrophil elastase (12 Activities)

Discover Target: ELANE

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PRTN3 Tchem Myeloblastin (1 Activities)

Discover Target: PRTN3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TNF Tclin Tumor necrosis factor (0 Activities)

Discover Target: TNF

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Images

ELISA: Adalimumab (anti-TNF-alpha) (A412002)

Adalimumab (anti-TNF-alpha) (A412002) - ELISA
Immobilized Recombinant Human TNF-α Protein (rp156007) at 1.0 μg/mL can bind Golimumab (anti-TNFa) (Ab175552) with the EC₅₀ of 5.78 ng/mL.

SEC: Adalimumab (anti-TNF-alpha) (A412002)

Adalimumab (anti-TNF-alpha) (A412002) - SEC
The purity of Adalimumab (anti-TNF-alpha) (A412002) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number	Certificate Type	Date	Item
ZJ24F0303693	Certificate of Analysis	Mar 26, 2024	A412002
ZJ24F0303692	Certificate of Analysis	Mar 26, 2024	A412002
ZJ24F0303691	Certificate of Analysis	Mar 26, 2024	A412002

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Adalimumab (anti-TNF-alpha) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to TNFSF2/TNFa, >95% (SDS-PAGE&SEC), high purity, Human IgG1, INHIBITOR of TNF-alpha inhibitor, INHIBITOR of TNF-alpha inhibitor

Basic Description

Taxonomic Classification

Product Properties

Associated Targets(Human)

Mechanisms of Action

Images

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

Alternative Products

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Reviews

Customer Reviews

Adalimumab (anti-TNF-alpha) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to TNFSF2/TNFa, >95% (SDS-PAGE&SEC), high purity, Human IgG1, INHIBITOR of TNF-alpha inhibitor, INHIBITOR of TNF-alpha inhibitor

Basic Description

Taxonomic Classification

Product Properties

Associated Targets(Human)

Mechanisms of Action

Images

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

Related Products

Alternative Products

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Reviews

Customer Reviews