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N-异丙基丙烯酰胺

553篇引用文献 COA COA
    级别和纯度:
  • ≥98%
  • 含稳定剂MEHQ
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货号 (SKU) 包装规格 是否现货 价格 数量
I106818-5g
 5g 现货 Stock Image
I106818-25g
 25g 现货 Stock Image
I106818-100g
 100g 现货 Stock Image
I106818-500g
 500g 现货 Stock Image
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丙烯酰胺 (8) 丙烯酸单体 (126) 聚合单体 (28) 聚合物/高分子试剂 (683)
main product photo

基本描述

英文别名 Isopropyl acrylamide | N-(1-Methylethyl)-2-propenamide | N-Iso-Propylacrylamide | N-Isopropyl acrylamide | NIPAAm | N-propan-2-ylprop-2-enamide
规格或纯度 ≥98%, 含稳定剂MEHQ
英文名称 N-Isopropylacrylamide
储存温度 2-8°C储存,充氩
运输条件 冰袋运输
产品介绍

N-异丙基丙烯酰胺 是丙烯酰胺衍生物单体，由于分子内有亲水性的酰胺基和疏水性的异丙基，使其均聚物具有较低的临界溶解温度等良好特性，主要用于制造具有感温特性的聚合物凝胶，例如：药物控释材料、酶的固体材料、脱水剂、浓缩剂等。还可用于制造变性胶乳、特种涂料、胶粘剂等。 N-异丙基丙烯酰胺用于制备聚(N-异丙基丙烯酰胺)（pNIPA、pNIPAAm、p?NIPAA 或 pNIPAm）热敏性聚合物或共聚物类水凝胶。含有 NIPAM 的聚合物在高于 33°C 时急剧收缩。 该单体用于制备热敏性、遇水可膨胀的水凝胶。

N-Isopropylacrylamide is used to produce poly(N-isopropylacrylamide) (pNIPA, pNIPAAm, pNIPAA or pNIPAm) thermosensitive polymer- or copolymer-based hydrogels. Polymers that contain NIPAM shrink dramatically above 33 °C. Monomer used in the preparation of thermally sensitive, water-swellable hydrogels.
纯度 ≥98%

关联靶点（人）

TSHR Tclin Thyroid stimulating hormone receptor (29986 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 504752765
EC号 218-638-5
分子类型 小分子
IIUPAC Name N-propan-2-ylprop-2-enamide
INCHI 1S/C6H11NO/c1-4-6(8)7-5(2)3/h4-5H,1H2,2-3H3,(H,7,8)
InChi Key QNILTEGFHQSKFF-UHFFFAOYSA-N
Smiles CC(C)NC(=O)C=C
Isomeric SMILES CC(C)NC(=O)C=C
分子量 113.16
Beilstein号 4(4)189
Reaxy-Rn 1744926
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1744926&ln=

化学和物理性质

溶解性 溶于水。
密度 0.877
敏感性 对湿度、热敏感
沸点 89-92°C
熔点 60-63°C
分子量 113.160 g/mol
XLogP3 0.900
氢键供体数Hydrogen Bond Donor Count 1
氢键受体数Hydrogen Bond Acceptor Count 1
可旋转键计数Rotatable Bond Count 2
精确质量Exact Mass 113.084 Da
单同位素质量Monoisotopic Mass 113.084 Da
拓扑极表面积Topological Polar Surface Area 29.100 Ų
重原子数Heavy Atom Count 8
形式电荷Formal Charge 0
复杂度Complexity 96.700
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS05,   GHS07
信号词 危险
危险声明

H302: 吞食有害

H318: 造成严重的眼睛损伤
预防措施声明

P264: 处理后要彻底洗手。

P270: 使用本产品时，请勿进食、饮水或吸烟。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P330: 漱口

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P501: 将内容物/容器处理到。。。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P301+P317: 如果被吞咽：请寻求医疗帮助。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。
WGK Germany 3
RTECS AS3675000
个人防护装备 dust mask type N95 (US),Eyeshields,Faceshields,Gloves

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批号(Lot Number) 证书类型 货号
L2312321 分析证书 I106818
G2529304 分析证书 I106818
G2529306 分析证书 I106818
G2529307 分析证书 I106818
G2529305 分析证书 I106818
F2525287 分析证书 I106818
F2525291 分析证书 I106818
F2525292 分析证书 I106818
F2525293 分析证书 I106818
D2517420 分析证书 I106818
D2517390 分析证书 I106818
D2517405 分析证书 I106818
E2323493 分析证书 I106818
E2323609 分析证书 I106818
E2323614 分析证书 I106818
B2512284 分析证书 I106818
B2512285 分析证书 I106818
B2512286 分析证书 I106818
B2512287 分析证书 I106818
L2404491 分析证书 I106818
L2404494 分析证书 I106818
L2404485 分析证书 I106818
L2404493 分析证书 I106818
J2410557 分析证书 I106818
J2410560 分析证书 I106818
J2410558 分析证书 I106818
H2408553 分析证书 I106818
H2408554 分析证书 I106818
H2408586 分析证书 I106818
H2408587 分析证书 I106818
I2227487 分析证书 I106818
E2408415 分析证书 I106818
E2408416 分析证书 I106818
E2408414 分析证书 I106818
H2412517 分析证书 I106818
E2408417 分析证书 I106818
C2420298 分析证书 I106818
C2420149 分析证书 I106818
C2420150 分析证书 I106818
C2420297 分析证书 I106818
C2420299 分析证书 I106818
C2416143 分析证书 I106818
C2416144 分析证书 I106818
C2416146 分析证书 I106818
L2312310 分析证书 I106818
L2312314 分析证书 I106818
L2312322 分析证书 I106818
I2321598 分析证书 I106818
I2321632 分析证书 I106818
I2321634 分析证书 I106818
H2312071 分析证书 I106818
E2323475 分析证书 I106818
E2323498 分析证书 I106818
E2323613 分析证书 I106818
E23231136 分析证书 I106818
K2217809 分析证书 I106818
K2217813 分析证书 I106818
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K2217828 分析证书 I106818
C2324554 分析证书 I106818
I2227488 分析证书 I106818
I2227489 分析证书 I106818
I2227491 分析证书 I106818

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技术文档和文章

用于细胞膜片组织工程的基于聚N-异丙基丙烯酰胺的智能表面
Categories: 技术文章
探索主题:
N-异丙基丙烯酰胺 PNIPAM 细胞膜片组织工程
作为智能药物递送系统的刺激响应材料
Categories: 技术文章
探索主题:
聚合物 癌症治疗 药物递送 刺激响应 二硫键
设计基于NIPAM（N-异丙基丙烯酰胺）的温敏和pH敏感聚合物
Categories: 技术文章
探索主题:
N-异丙基丙烯酰胺 药物递送 组织工程 聚（N-异丙基丙烯酰胺） 温敏聚合物 pH敏感聚合物 刺激响应型聚合物 生物偶联 生物传感器 生物分离
Designing Temperature and pH Sensitive NIPAM Based Polymers
Categories: 技术文章
探索主题:
PNIPAM N-Isopropylacrylamide Drug delivery Tissue engineering NIPAM Poly(N-isopropylacrylamide) Temperature-Sensitive Polymer pH-Sensitive Polymer Stimulus-Responsive Polymer Bioconjugation Biosensor Bioseparation
Designing Temperature and pH Sensitive NIPAM Based Polymers
Categories: 技术文章
探索主题:
PNIPAM N-Isopropylacrylamide Drug delivery Tissue engineering NIPAM Poly(N-isopropylacrylamide) Temperature-Sensitive Polymer pH-Sensitive Polymer Stimulus-Responsive Polymer Bioconjugation Biosensor Bioseparation
单体合成的连续流制造
Categories: 技术文章
探索主题:
单体合成 连续流制造 眼科材料制造 生物医用 纳米粒子合成
Continuous Flow Manufacturing for Monomer Synthesis
Categories: 技术文章
探索主题:
Monomer Synthesis Continuous Flow Manufacturing Ophthalmic Material Manufacturing Biomedical Nanoparticle Synthesis
Continuous Flow Manufacturing for Monomer Synthesis
Categories: 技术文章
探索主题:
Monomer Synthesis Continuous Flow Manufacturing Ophthalmic Material Manufacturing Biomedical Nanoparticle Synthesis

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此产品的引用文献

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引用文献

1. R Yoshida.  (1998-04-29)  [Controlled release using temperature-responsive poly(N-isopropylacrylamide) gel]..  Nihon rinsho. Japanese journal of clinical medicine,  56  ((3)): (670-674).  [PMID:9549354]
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12. Subrayal M Reddy,Quan T Phan,Hazim El-Sharif,Lata Govada,Derek Stevenson,Naomi E Chayen.  (2012-10-31)  Protein crystallization and biosensor applications of hydrogel-based molecularly imprinted polymers..  Biomacromolecules,  13  ((12)): (3959-3965).  [PMID:23106501]
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