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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| E130023-50mg |
50mg |
现货 ![]() |
| |
| E130023-250mg |
250mg |
现货 ![]() |
| |
| E130023-1g |
1g |
现货 ![]() |
| |
| E130023-5g |
5g |
现货 ![]() |
| |
| E130023-25g |
25g |
现货 ![]() |
| |
| E130023-100g |
100g |
现货 ![]() |
|
| 别名 | (-)-顺式-3,3',4',5,7-五羟基黄烷 | (2R,3R)-2-(3,4-二羟基苯基)-3,4-二氢-1(2H)-苯并吡喃-3,5,7-三醇 | (-)-表儿茶素 | (-)-顺-3,3',4',5,7-五羟基黄烷 | (−)-表儿茶素 | 表儿茶精 |
|---|---|
| 英文别名 | .alpha. Catechin | A12043 | KBio2_005775 | 1,2-Ethanedisulfonicacid | 2-(3,4-Dihydroxyphenyl)-2,3,4-trihydro-3,5,7-trihydroxychromene | Acacatechin | Spectrum_000159 | CCG-38571 | CCRIS 7097 | s4723 | Tetradecanoic acid, 1-methylethyl ester | MFCD00008042 |
| 规格或纯度 | Moligand™, ≥97%(HPLC) |
| 英文名称 | (-)-Epicatechin |
| 生化机理 | 表儿茶素能增强心力衰竭患者的骨骼肌结构,最大限度地降低心脏代谢风险。它可用于治疗肌肉疏松症。表儿茶素能降低肌生成素和β-半乳糖苷酶,提高肌肉生长标志物的水平。 |
| 来源 | Tea |
| 储存温度 | 2-8°C储存,充氩 |
| 运输条件 | 冰袋运输 |
| 产品介绍 |
表儿茶素是一种黄烷醇化合物。可可产品富含表儿茶素。表儿茶素可增强心力衰竭患者的骨骼肌结构,并最大限度降低心脏代谢风险。它可用于治疗肌肉减少症。表儿茶素可降低肌肉生长抑制素和β-半乳糖苷酶,并提高肌肉生长标志物的水平。抗氧剂,发现于巧克力中 (-)-Epicatechin 抑制环加氧酶-1 (COX-1) , IC50为 3.2 μM。(-)-Epicatechin 通过阻断 NF-κB 的 p65 亚基的核定位来抑制 IL-1β 诱导的 iNOS 表达。 Epicatechin is a flavanol. Cacao products are rich in epicatechin. Epicatechin enhances the skeletal muscle structure in heart failure patients and minimises the cardiometabolic risks. It can be used for treating sarcopenia. Epicatechin reduces myostatin and β-galactosidase and increases the level of markers of muscle growth. Product description: (-)-Epicatechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB. Application: (−)-Epicatechin (EC) has been used: as an antioxidant to downregulate nicotinamide adenine dinucleotide phosphate hydrogen (NADPH) oxidase and improve insulin sensitivity in in vivo (high fat-fed mice) and in vitro (HepG2 cells) studies to study its effect on blood pressure, nitric oxide synthase (NOS) activity and anxiety-like behavior on borderline hypertensive rat (BHR) models to test its effect on neuronal survival in the hippocampus of middle-aged rats on swimming training, under oxidative stress to study its antioxidant activity in dark chocolate as a characteristic compound in polyphenols analysis |
| 纯度 | ≥97%(HPLC) |
| 活性类型 | Relation | Activity value | Units | Action Type | 期刊 | PubMed Id | doi | Assay Aladdin ID |
|---|
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| PubChem SID | 488184683 |
|---|---|
| EC号 | 207-710-1 |
| 分子类型 | 小分子 |
| IIUPAC Name | (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol |
| INCHI | 1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15-/m1/s1 |
| InChi Key | PFTAWBLQPZVEMU-UKRRQHHQSA-N |
| Smiles | C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O |
| Isomeric SMILES | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O |
| 关联CAS | 490-46-0,17334-50-8 |
| MeSH Entry Terms | (+)-Catechin;(+)-Cyanidanol;(+)-Cyanidanol-3;(-)-Epicatechin;(2R,3R)-2-(3,4-Dihydroxyphenyl)-3,5,7-chromanetriol;2H-1-Benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R-cis)-;3,3',4',5,7-Flavanpentol;Catechin;Catechinic Acid;Catechuic Acid; |
| 分子量 | 290.27 |
| Beilstein号 | 92760 |
| Reaxy-Rn | 6069926 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6069926&ln= |
| 溶解性 | Soluble in acetone:water (1:1, 10 mg/ml), DMSO (100 mM), methanol, DMF (~12.5 mg/ml), and water (partly)., Soluble in acetone:water (1:1, 10 mg/ml), DMSO (100 mM), methanol, DMF (~12.5 mg/ml), and water (partly)., |
|---|---|
| 密度 | 1.593 |
| 敏感性 | 对热和空气敏感 |
| 比旋光度 | -62° (C=0.1,MeOH) |
| 熔点 | 240°C |
| 分子量 | 290.270 g/mol |
| XLogP3 | 0.400 |
| 氢键供体数Hydrogen Bond Donor Count | 5 |
| 氢键受体数Hydrogen Bond Acceptor Count | 6 |
| 可旋转键计数Rotatable Bond Count | 1 |
| 精确质量Exact Mass | 290.079 Da |
| 单同位素质量Monoisotopic Mass | 290.079 Da |
| 拓扑极表面积Topological Polar Surface Area | 110.000 Ų |
| 重原子数Heavy Atom Count | 21 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 364.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 2 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS07 |
|---|---|
| 信号词 | 警告 |
| 危险声明 |
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理(请参阅此标签上的...)。 P302+P352: 如皮肤沾染:用水充分清洗。 P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。 P405: 密闭存放 P403+P233: 存放在通风良好的地方。保持容器密闭。 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续:寻求医疗帮助。 P332+P317: 如果出现皮肤刺激:请寻求医疗帮助。 P319: 如果你感到不适,请寻求医疗帮助。 |
| WGK Germany | 3 |
| RTECS | KB3745000 |
| 个人防护装备 | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | E130023 | |
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| 1. Yuqing Zhong, Yongling Lu, Lishuang Lv. (2023) Theanine in Tea: An Effective Scavenger of Single or Multiple Reactive Carbonyl Species at the Same Time. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 71 (45): (17153–17162). [PMID:37906124] [10.1021/acs.jafc.3c05483] |
| 2. Yating Guo, Yili Shen, Boya Hu, Huichun Ye, Haowei Guo, Qiang Chu, Ping Chen. (2023) Decoding the Chemical Signatures and Sensory Profiles of Enshi Yulu: Insights from Diverse Tea Cultivars. Plants-Basel, 12 (21): (3707). [PMID:37960063] [10.3390/plants12213707] |
| 3. Yingyi Huang, Huahong Liu, Xiaohua Zhang, Yuxin Wu, Zhusheng Liu, Yuelan Pang, Renjun Liu, Chun Yang, Jinfang Nie. (2023) Impact of storage time on non-volatile metabolites and fungal communities in Liupao tea using LC-MS based non-targeted metabolomics and high-throughput sequencing. FOOD RESEARCH INTERNATIONAL, 174 (113615). [PMID:37986470] [10.1016/j.foodres.2023.113615] |
| 4. Hao-Xiang Gao, Nan Chen, Qiang He, Bi Shi, Wei-Cai Zeng. (2024) Effects of structural characteristics of phenolic compounds on oxidation of glycerol trioleate: Action rule and mechanism. FOOD CHEMISTRY, 433 (137361). [PMID:37688816] [10.1016/j.foodchem.2023.137361] |
| 5. Xiaoyu Yang, Zhichun Bi, Chenghui Yin, Shuyi Zhang, Donghui Song, Hui Huang, Yongxin Li. (2024) A colorimetric sensor array based on peroxidase activity nanozyme for the highly efficient differential sensing of tea polyphenols and Tieguanyin adulteration. FOOD CHEMISTRY, 432 (137265). [PMID:37657343] [10.1016/j.foodchem.2023.137265] |
| 6. Cheng Guo, Wangyang Shen, Weiping Jin, Xiwu Jia, Zhili Ji, Jinling Li, Bin Li. (2023) Dynamic Formation of Green Tea Cream and the Identification of Key Components Using the “Knock-Out/Knock-In” Method. Foods, 12 (16): (2987). [PMID:37627986] [10.3390/foods12162987] |
| 7. Xiao-Hua Zhang, Xiang-Dong Qing, Jing-Jing Zheng, Yan Yu, Jiaojiao Huang, Chao Kang, Zhi Liu. (2023) Aqueous two-phase systems coupled with chemometrics-enhanced HPLC-DAD for simultaneous extraction and determination of flavonoids in honey. Food Chemistry-X, 19 (100766). [PMID:37780266] [10.1016/j.fochx.2023.100766] |
| 8. Xiaojuan Chen, Bojia Li, Sicheng Ji, Di Wu, Bing Cui, Xingling Ren, Bin Zhou, Bin Li, Hongshan Liang. (2023) Small molecules interfacial assembly regulate the crystallization transition process for nobiletin stabilization. FOOD CHEMISTRY, 426 (136519). [PMID:37329798] [10.1016/j.foodchem.2023.136519] |
| 9. Su Zhou, Jiaying Yang, Yani Pan, Xinyu Feng, Hao Hu, Shicheng Ma, Cansong Ou, Fangyuan Fan, Shuying Gong, Yuefei Wang, Ping Chen, Qiang Chu. (2023) Pu’ er raw tea extract alleviates DSS-induced colitis in mice by restoring intestinal barrier function and maintaining gut microbiota homeostasis. Food Bioscience, 53 (102750). [10.1016/j.fbio.2023.102750] |
| 10. Chi Zhao, Fengju Zhang, Shanbo Chen, Wen Hu, Ling Dong, Yuejun Zhao, Mei Han, Zhihua Li. (2023) Effects of drying methods on the quality of Hanyuan Zanthoxylum bungeanum based on physicochemical and functional metabolite analysis. LWT-FOOD SCIENCE AND TECHNOLOGY, 180 (114674). [10.1016/j.lwt.2023.114674] |
| 11. Wang Qiaolin, Xu Lihe, Qin Zhengbo, Yang Xinyan, Zheng Xianfeng. (2023) Potential use of LIAD time-of-flight mass spectrometry for the detection of biomolecules: An example of detecting nucleobases in DNA. AIP Advances, 13 (3): [10.1063/5.0137046] |
| 12. Fanghua Guo, Li Peng, Hua Xiong, Rong Tsao, Hua Zhang, Li Jiang, Yong Sun. (2023) Bioaccessibility and transport of lentil hull polyphenols in vitro, and their bioavailability and metabolism in rats. FOOD RESEARCH INTERNATIONAL, 167 (112634). [PMID:37087206] [10.1016/j.foodres.2023.112634] |
| 13. Huiqun Fan, Mingshun Chen, Taotao Dai, Lizhen Deng, Chengmei Liu, Wei Zhou, Jun Chen. (2023) Phenolic compounds profile of Amomum tsaoko Crevost et Lemaire and their antioxidant and hypoglycemic potential. Food Bioscience, 52 (102508). [10.1016/j.fbio.2023.102508] |
| 14. Jianhui Zhu, Jingyang Yu, Bingjie Zhang, Changsheng Li, Jianli Wang, Jiawen Ji, Desheng Liu, Rumin Gao, Jianzhang Li, Yongqiang Ma. (2023) Hydrophobic-action-driven removal of six organophosphorus pesticides from tea infusion by modified carbonized bacterial cellulose. FOOD CHEMISTRY, 412 (135546). [PMID:36716625] [10.1016/j.foodchem.2023.135546] |
| 15. Lixia Yang, Zhendong Lu, Jian Lu, Dianhui Wu. (2022) Evaluation of the antioxidant characteristics of craft beer with green tea. JOURNAL OF FOOD SCIENCE, 88 (2): (625-637). [PMID:36576119] [10.1111/1750-3841.16441] |
| 16. Zhangfeng Zhao, Zhengwei Dai, Xuming Jiang, Liaoyuan Yu, Meijuan Hu, Jiyu Peng, Fei Zhou. (2023) Influence and optimization of long-time superfine grinding on the physicochemical features of green tea powder. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 117 (105124). [10.1016/j.jfca.2022.105124] |
| 17. Mang-Mang Li, Yi-Ting Chen, Jin-Cang Ruan, Wen-Jun Wang, Ji-Guang Chen, Qing-Feng Zhang. (2023) Structure-activity relationship of dietary flavonoids on pancreatic lipase. Current Research in Food Science, 6 (100424). [PMID:36618100] [10.1016/j.crfs.2022.100424] |
| 18. Han Wang, Lu Chen, Shuang Wu, Weiping Jin, Wangyang Shen, Zhongze Hu, Wenjing Huang, Gang Liu. (2023) Improve stability and application of rice oil bodies via surface modification with ferulic acid, (-)-epicatechin, and phytic acid. FOOD CHEMISTRY, 409 (135274). [PMID:36586252] [10.1016/j.foodchem.2022.135274] |
| 19. Xinyu Fang, Jiali Ma, Chenjie Gu, Wei Xiong, Tao Jiang. (2023) Synchronous enhancement of electromagnetic and chemical effects-induced quantitative adsorptive detection of quercetin based on flexible polymer-silver-ZIF-67 SERS substrate. SENSORS AND ACTUATORS B-CHEMICAL, 378 (133176). [10.1016/j.snb.2022.133176] |
| 20. Shuwen Li, Zhiguo Wang, Siyi Chen, Jialin Gu, Yanping Ma, Jiangang Jiang, Rui Zhang, Dan Zhang, Yiping Wang, He Wang. (2023) Ratiometric fluorescence sensing based on rare-earth upconversion nanoparticles for the rapid identification of antioxidant capacity. NEW JOURNAL OF CHEMISTRY, 47 (4): (2079-2085). [10.1039/D2NJ05429A] |
| 21. Xiao-Hua Zhang, Hui-Na Cui, Jing-Jing Zheng, Xiang-Dong Qing, Kai-Long Yang, Ya-Qian Zhang, Lu-Meng Ren, Le-Yuan Pan, Xiao-Li Yin. (2023) Discrimination of the harvesting season of green tea by alcohol/salt-based aqueous two-phase systems combined with chemometric analysis. FOOD RESEARCH INTERNATIONAL, 163 (112278). [PMID:36596188] [10.1016/j.foodres.2022.112278] |
| 22. Hui Jiang, Fei Wu, Xi Jiang, Yun-Feng Pu, Li-Rong Shen, Cui-Yun Wu, Hong-Jin Bai. (2022) Antioxidative, cytoprotective and whitening activities of fragrant pear fruits at different growth stages. Frontiers in Nutrition, 9 (1020855). [PMID:36245497] [10.3389/fnut.2022.1020855] |
| 23. Yao Fan, Siying Che, Lei Zhang, Chunsong Zhou, Haiyan Fu, Yuanbin She. (2022) Dual channel sensor array based on ZnCdSe QDs – KMnO4: An effective tool for analysis of catechins and green teas. FOOD RESEARCH INTERNATIONAL, 160 (111734). [PMID:36076421] [10.1016/j.foodres.2022.111734] |
| 24. Guanghe Zhao, Ruifen Zhang, Lihong Dong, Lei Liu, Fei Huang, Xuchao Jia, Mei Deng, Jianwei Chi, Yongxuan Ma, Yanxia Chen, Qin Ma, Mingwei Zhang. (2022) Bound phenolics in rice bran dietary fibre released by different chemical hydrolysis methods: content, composition and antioxidant activities. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 57 (9): (5909-5916). [10.1111/ijfs.15915] |
| 25. Su Xuexia, Bai Cuihua, Wang Xianghe, Liu Huilin, Zhu Yongcong, Wei Leping, Cui Zixiao, Yao Lixian. (2022) Potassium Sulfate Spray Promotes Fruit Color Preference via Regulation of Pigment Profile in Litchi Pericarp. Frontiers in Plant Science, 13 [PMID:35774808] [10.3389/fpls.2022.925609] |
| 26. He Wen-Jing, Chen Nan, Yu Zhi-Long, Sun Qun, He Qiang, Zeng Wei-Cai. (2022) Effect of Structure Complexity of Catechins on the Properties of Glutenin: the Rule, Action Mechanism and Application. Food Biophysics, 17 (4): (586-597). [10.1007/s11483-022-09744-9] |
| 27. Wen-Jing He, Nan Chen, Zhi-Long Yu, Qun Sun, Qiang He, Wei-Cai Zeng. (2022) Gliadin interacted with tea polyphenols: potential application and action mechanism. INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION, 73 (6): (786-799). [PMID:35603582] [10.1080/09637486.2022.2078283] |
| 28. Sen Li, Yu Chen, Yu Zhang, Hongyan Lv, Lei Luo, Shuo Wang, Xiao Guan. (2022) Polyphenolic Extracts of Coffee Cherry Husks Alleviated Colitis-Induced Neural Inflammation via NF-κB Signaling Regulation and Gut Microbiota Modification. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (21): (6467–6477). [PMID:35588304] [10.1021/acs.jafc.2c02079] |
| 29. Ya-Fang Shang, Jun-Hao Miao, Jia Zeng, Tian-Hua Zhang, Rui-Ming Zhang, Bing-Yan Zhang, Chao Wang, Yi-Long Ma, Xiang-Li Niu, Xiao-Long Ni, Zhao-Jun Wei. (2022) Evaluation of digestibility differences for apple polyphenolics using in vitro elderly and adult digestion models. FOOD CHEMISTRY, 390 (133154). [PMID:35584576] [10.1016/j.foodchem.2022.133154] |
| 30. Songjie Li, Weimin Zhang, Ruimin Wang, Congfa Li, Xue Lin, Lu Wang. (2022) Screening and identification of natural α-glucosidase and α-amylase inhibitors from partridge tea (Mallotus furetianus Muell-Arg) and in silico analysis. FOOD CHEMISTRY, 388 (133004). [PMID:35483282] [10.1016/j.foodchem.2022.133004] |
| 31. Linjun Li, Jinsuo Lu, Heliang Pang, Zhiqiang Zhang, Jing Yang, Pengpeng Li, Xiaoyu Yan, Miaomiao Fan. (2023) New insight into scale inhibition during tea brewing: Ca2+/Mg2+ complexing and alkalinity consumption. Journal of Environmental Sciences, 124 (901). [PMID:36182193] [10.1016/j.jes.2022.02.014] |
| 32. Zhao Lu, Song Zhongbang, Wang Bingwu, Gao Yulong, Shi Junli, Sui Xueyi, Chen Xuejun, Zhang Yihan, Li Yongping. (2022) R2R3-MYB Transcription Factor NtMYB330 Regulates Proanthocyanidin Biosynthesis and Seed Germination in Tobacco (Nicotiana tabacum L.). Frontiers in Plant Science, 12 [PMID:35111187] [10.3389/fpls.2021.819247] |
| 33. Hui-Wen Gu, Xiao-Li Yin, Tian-Qin Peng, Yuan Pan, Hui-Na Cui, Zhi-Quan Li, Weiqing Sun, Baomiao Ding, Xian-Chun Hu, Zi-Hong Zhang, Zhi Liu. (2022) Geographical origin identification and chemical markers screening of Chinese green tea using two-dimensional fingerprints technique coupled with multivariate chemometric methods. FOOD CONTROL, 135 (108795). [10.1016/j.foodcont.2021.108795] |
| 34. Qian Li, Jing Li, Mengran Duan, Lu Liu, Yinxin Fu, David Julian McClements, Tiantian Zhao, Hongyi Lin, Jinglan Shi, Xiaoqiang Chen. (2022) Impact of food additive titanium dioxide on the polyphenol content and antioxidant activity of the apple juice. LWT-FOOD SCIENCE AND TECHNOLOGY, 154 (112574). [10.1016/j.lwt.2021.112574] |
| 35. Xiao Ma, Manman Li, Guicong Lu, Ruihong Wang, Yunmin Wei, Yanfeng Guo, Yongxiong Yu, Caode Jiang. (2021) Anti-inflammation of epicatechin mediated by TMEM35A and TMPO in bovine mammary epithelial cell line cells and mouse mammary gland. JOURNAL OF DAIRY SCIENCE, 104 (12925). [PMID:34593235] [10.3168/jds.2021-20571] |
| 36. Qian Li, Mengran Duan, Lu Liu, Xiaoqiang Chen, Yinxin Fu, Jing Li, Tiantian Zhao, David Julian McClements. (2021) Impact of Polyphenol Interactions with Titanium Dioxide Nanoparticles on Their Bioavailability and Antioxidant Activity. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 69 (33): (9661–9670). [PMID:34376052] [10.1021/acs.jafc.1c01970] |
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