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L-香芹醇,顺反异构体混合物

    级别和纯度:
  • ≥97%
有货

库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
C102530-1g
1g 期货 Stock Image
C102530-10g
10g 现货 Stock Image
C102530-50g
50g 现货 Stock Image
C102530-250g
250g 期货 Stock Image
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代谢物 (8911)

基本描述

别名 葛缕醇
英文别名 HY-W017370 | p-Mentha-1,8-dien-6-ol | p-Mentha-6, l- | 2-06-00-00102 (Beilstein Handbook Reference) | MFCD00062993 | SCHEMBL56868 | 2-Methyl-5-(1-propen-2-yl)-2-cyclohexenol | 2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-ol | FT-0715464 | p-Mentha-1(6),8-di
规格或纯度 ≥97%
英文名称 (-)-Carveol, mixture of isomers
运输条件 常规运输
产品介绍


L -香芹酚,顺和反式的混合物,是一种环萜烯醇,可用作调味剂和香料成分。


纯度 ≥97%

关联靶点(人)

TRPV3 Tchem 瞬时受体电位阳离子通道亚家族V成员3(Transient receptor potential cation channel subfamily V member 3) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
TSHR Tclin Thyroid stimulating hormone receptor (29986 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点(其它种属)

FTL Ferritin light chain (43324 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 488180431
EC号 202-757-4
分子类型 小分子
IIUPAC Name 2-methyl-5-prop-1-en-2-ylcyclohex-2-en-1-ol
INCHI 1S/C10H16O/c1-7(2)9-5-4-8(3)10(11)6-9/h4,9-11H,1,5-6H2,2-3H3
InChi Key BAVONGHXFVOKBV-UHFFFAOYSA-N
Smiles CC1=CCC(CC1O)C(=C)C
Isomeric SMILES CC1=CCC(CC1O)C(=C)C
分子量 152.23
Reaxy-Rn 1861032
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1861032&ln=

化学和物理性质

溶解性 Partly soluble in water. Soluble in alcohol, ethanol and DMSO.
密度 0.958
折光率 1.496
闪点(℉) 208.4 °F
闪点(℃) 98°C
沸点 226-227°C
分子量 152.230 g/mol
XLogP3 2.100
氢键供体数Hydrogen Bond Donor Count 1
氢键受体数Hydrogen Bond Acceptor Count 1
可旋转键计数Rotatable Bond Count 1
精确质量Exact Mass 152.12 Da
单同位素质量Monoisotopic Mass 152.12 Da
拓扑极表面积Topological Polar Surface Area 20.200 Ų
重原子数Heavy Atom Count 11
形式电荷Formal Charge 0
复杂度Complexity 191.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 2
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性(GHS)

象形图 GHS07
信号词 警告
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激

预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P264: 处理后要彻底洗手。

P271: 仅在室外或通风良好的地方使用。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P321: 特殊处理(请参阅此标签上的...)。

P302+P352: 如皮肤沾染:用水充分清洗。

P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。

P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。

P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。

P405: 密闭存放

P403+P233: 存放在通风良好的地方。保持容器密闭。

P501: 将内容物/容器处理到。。。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P337+P317: 如果眼睛刺激持续:寻求医疗帮助。

P332+P317: 如果出现皮肤刺激:请寻求医疗帮助。

P319: 如果你感到不适,请寻求医疗帮助。

WGK Germany 2
RTECS OS8400000
个人防护装备 Eyeshields,full-face respirator (US),Gloves,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter

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C of A & Other Certificates(BSE/TSE, COO):
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找到7个结果

批号(Lot Number) 证书类型 货号
F1904114 分析证书 C102530
L2212249 分析证书 C102530
G2507073 分析证书 C102530
C2212367 分析证书 C102530
C2212407 分析证书 C102530
C2212418 分析证书 C102530
C2320556 分析证书 C102530

此产品的引用文献

引用文献

1. Parnas M, Peters M, Dadon D, Lev S, Vertkin I, Slutsky I, Minke B.  (2009)  Carvacrol is a novel inhibitor of Drosophila TRPL and mammalian TRPM7 channels..  Cell Calcium,  45  (3): (300-9).  [PMID:19135721]
2. P L Crowell,W S Kennan,J D Haag,S Ahmad,E Vedejs,M N Gould.  (1992-07-01)  Chemoprevention of mammary carcinogenesis by hydroxylated derivatives of d-limonene..  Carcinogenesis,  13  ((7)): (1261-1264).  [PMID:1638695]
3. M J van der Werf,A M Boot.  (2000-06-01)  Metabolism of carveol and dihydrocarveol in Rhodococcus erythropolis DCL14..  Microbiology (Reading, England),  146   (( Pt 5)): (1129-1141).  [PMID:10832640]
4. M Wüst,D B Little,M Schalk,R Croteau.  (2001-05-23)  Hydroxylation of limonene enantiomers and analogs by recombinant (-)-limonene 3- and 6-hydroxylases from mint (Mentha) species: evidence for catalysis within sterically constrained active sites..  Archives of biochemistry and biophysics,  387  ((1)): (125-136).  [PMID:11368174]
5. Mitsuo Miyazawa,Masaki Shindo,Tsutomu Shimada.  (2002-01-22)  Sex differences in the metabolism of (+)- and (-)-limonene enantiomers to carveol and perillyl alcohol derivatives by cytochrome p450 enzymes in rat liver microsomes..  Chemical research in toxicology,  15  ((1)): (15-20).  [PMID:11800592]
6. Mitsuo Miyazawa,Masaki Shindo,Tsutomu Shimada.  (2002-04-16)  Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes..  Drug metabolism and disposition: the biological fate of chemicals,  30  ((5)): (602-607).  [PMID:11950794]
7. Carla C C R de Carvalho,M Manuela R da Fonseca.  (2007-07-10)  Preventing biofilm formation: promoting cell separation with terpenes..  FEMS microbiology ecology,  61  ((3)): (406-413).  [PMID:17617221]
8. S P Bhatia,D McGinty,C S Letizia,A M Api.  (2008-07-22)  Fragrance material review on carveol..  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,  46 Suppl 11  (S85-S87).  [PMID:18640224]
9. Devin R Polichuk,Yansheng Zhang,Darwin W Reed,Janice F Schmidt,Patrick S Covello.  (2010-07-14)  A glandular trichome-specific monoterpene alcohol dehydrogenase from Artemisia annua..  Phytochemistry,  71  ((11-12)): (1264-1269).  [PMID:20621795]
10. Vuy H Li,Abid Mallick,Craig Concannon,Vuy Y Li.  (2011-05-25)  Wide complex tachycardia causing congestive heart failure..  Pacing and clinical electrophysiology : PACE,  34  ((9)): (1154-1157).  [PMID:21605135]
11. Tomoko Iizuka,Yasuhiro Nishikawa,Yoshihiro Mori,Natsuko Zenimura,Takuyuki Matsumoto,Katsutoshi Hiramatsu,Masahiro Komiya.  (2011-06-18)  Artist® tablets (carvedilol) for hypertensive patients in Japan: results of a long-term special survey..  Drugs in R&D,  11  ((2)): (191-205).  [PMID:21679008]
12. M Govindarajan,R Sivakumar,M Rajeswari,K Yogalakshmi.  (2011-12-06)  Chemical composition and larvicidal activity of essential oil from Mentha spicata (Linn.) against three mosquito species..  Parasitology research,  110  ((5)): (2023-2032).  [PMID:22139403]
13. Hiroki Kawasaki,Kotaro Mizuta,Tsugumi Fujita,Eiichi Kumamoto.  (2013-01-29)  Inhibition by menthol and its related chemicals of compound action potentials in frog sciatic nerves..  Life sciences,  92  ((6-7)): (359-367).  [PMID:23352972]
14. Hatice Büşra Konuk,Bengü Ergüden.  (2020-03-21)  Phenolic -OH group is crucial for the antifungal activity of terpenoids via disruption of cell membrane integrity..  Folia microbiologica,  65  ((4)): (775-783).  [PMID:32193708]
15. Imran Malik,Fawad Ali Shah,Tahir Ali,Zhen Tan,Abdullah Alattar,Najeeb Ullah,Arif-Ullah Khan,Reem Alshaman,Shupeng Li.  (2020-07-28)  Potent Natural Antioxidant Carveol Attenuates MCAO-Stress Induced Oxidative, Neurodegeneration by Regulating the Nrf-2 Pathway..  Frontiers in neuroscience,  14  (659-659).  [PMID:32714135]
16. A T Karlberg,K Magnusson,U Nilsson.  (1992-05-01)  Air oxidation of d-limonene (the citrus solvent) creates potent allergens..  Contact dermatitis,  26  ((5)): (332-340).  [PMID:1395597]
17. B M Magnusson,P Runn,L O Koskinen.  (1997-07-01)  Terpene-enhanced transdermal permeation of water and ethanol in human epidermis..  Acta dermato-venereologica,  77  ((4)): (264-267).  [PMID:9228215]
18. W A Duetz,A H Fjällman,S Ren,C Jourdat,B Witholt.  (2001-05-26)  Biotransformation of D-limonene to (+) trans-carveol by toluene-grown Rhodococcus opacus PWD4 cells..  Applied and environmental microbiology,  67  ((6)): (2829-2832).  [PMID:11375201]
19. Aleem U Khand,Andrew C Rankin,William Martin,Jacqueline Taylor,Islay Gemmell,John G F Cleland.  (2003-12-10)  Carvedilol alone or in combination with digoxin for the management of atrial fibrillation in patients with heart failure?.  Journal of the American College of Cardiology,  42  ((11)): (1944-1951).  [PMID:14662257]
20. Marion Kamphoff,Tobias Thiele,Benno Kunz.  (2008-01-16)  Influence of different extraction parameters on a solid-phase dynamic extraction for the gas chromatographic determination of d-limonene degradation products by using a fractional factorial design..  Journal of AOAC International,  90  ((6)): (1623-1627).  [PMID:18193739]
21. Jenna L E Morrish,Andrew J Daugulis.  (2008-03-11)  Inhibitory effects of substrate and product on the carvone biotransformation activity of Rhodococcus erythropolis..  Biotechnology letters,  30  ((7)): (1245-1250).  [PMID:18327538]
22. Jenna L E Morrish,Andrew J Daugulis.  (2008-06-12)  Improved reactor performance and operability in the biotransformation of carveol to carvone using a solid-liquid two-phase partitioning bioreactor..  Biotechnology and bioengineering,  101  ((5)): (946-956).  [PMID:18546419]
23. S P Bhatia,D McGinty,C S Letizia,A M Api.  (2008-07-22)  Fragrance material review on laevo-carveol..  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,  46 Suppl 11  (S88-S90).  [PMID:18640177]
24. Staffan Johansson,Theres Redeby,Timothy M Altamore,Ulrika Nilsson,Anna Börje.  (2009-09-04)  Mechanistic proposal for the formation of specific immunogenic complexes via a radical pathway: a key step in allergic contact dermatitis to olefinic hydroperoxides..  Chemical research in toxicology,  22  ((11)): (1774-1781).  [PMID:19725554]
25. Juan Carlos R Gonçalves,Aron de Miranda H Alves,Anna Erika V de Araújo,Jader Santos Cruz,Demetrius Antônio Machado Araújo.  (2010-07-31)  Distinct effects of carvone analogues on the isolated nerve of rats..  European journal of pharmacology,  645  ((1-3)): (108-112).  [PMID:20670618]
26. Xiaojiao Zheng, Weiwei Ma, Qihui Wang, Yaping Xu, Yukun Yang, Shu Qin, Xu Jing.  (2024)  Development of self-dispersion ferrofluid-based dispersive liquid–liquid microextraction for determining chiral fungicide hexaconazole in water, tea, and juice using high-performance liquid chromatography.  MICROCHEMICAL JOURNAL,  196  (109593).  [10.1016/j.microc.2023.109593]
27. Guo-Feng Mao, Xiao-Chang Mo, Hatem Fouad, Ghulam Abbas, Jian-Chu Mo.  (2018)  Attraction behaviour of Anagrus nilaparvatae to remote lemongrass (Cymbopogon distans) oil and its volatile compounds.  NATURAL PRODUCT RESEARCH,  [PMID:28503948] [10.1080/14786419.2017.1326486]
28. Wenbin Xiao, Jiajing Guo, Yanjiao Fu, Zixuan Li, Tongping Zhang, Mingwang He, Ting Liu, Yangbo Xiao, Xuebo Shang, Fuhua Fu, Gaoyang Li, Donglin Su, Zhipeng Gao, Yang Shan.  (2025)  Long-term study of Citrus changshan-huyou Y.B. Chang essential oil: Chemical transformations and their impact on antibacterial efficacy.  FOOD CHEMISTRY,  474  (143118).  [PMID:39908813] [10.1016/j.foodchem.2025.143118]

溶液计算器