基本信息

产品名称	Recombinant CD19 Antibody
别名	白细胞分化抗原19 \| B细胞抗原受体辅助受体 \| CD19 抗体 \| Anti-CD19抗体 \| 小鼠抗人CD19抗体
英文别名	B4 \| B-lymphocyte antigen CD19 \| B-lymphocyte surface antigen B4 \| CD19 antigen \| CD19 molecule \| CD19 \| CVID3 \| Differentiation antigen CD19 \| Leu-12 \| MGC12802 \| T-cell surface antigen Leu-12 \| Antibody deficiency due to defect in CD19 antibody \| Antibo
规格或纯度	无动物源, 无载体, 重组, ExactAb™, 无叠氮钠, 已验证, 高性能, ≥95%(SDS-PAGE), 见COA
生化机理	Functions as a coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2+ stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells (By similarity). Required for normal B cell differentiation and proliferation in response to antigen challenges. Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge.
宿主种属	小鼠(Mouse)
特异性	Human CD19
种属反应性	人(Human)
免疫原	NALM1 + NALM16 cells
阳性对照	Flow Cytometry: Human peripheral blood lymphocytes
偶联	Unconjugated

产品属性

克隆类型	重组抗体
Format	Whole IgG
轻链亚型	kappa
纯化方法	Protein A purified
储存缓冲液	PBS, pH 6.0
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融。
分子类型	抗体

关联靶点（人）

CD19 Tclin B淋巴细胞抗原CD19(B-lymphocyte antigen CD19) (0 活性数据)

点击查看靶蛋白信息： CD19

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: Recombinant CD19 Antibody (Ab219601)

Recombinant CD19 Antibody (Ab219601) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD19 with Recombinant CD19 Antibody (Ab219601) (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Mouse IgG Isotype Control Antibody (Ab170221) (left panel) and detected with Alexa Fluor 488-conjugated affinipure goat anti-Mouse IgG.

Flow Cytometry: Recombinant CD19 Antibody (Ab219601)

Recombinant CD19 Antibody (Ab219601) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD19 (red) with Recombinant CD19 Antibody (Ab219601) at 0.5 μg/mL for 1 hour at 4°C, and detected with Alexa Fluor 488-conjugated affinipure goat anti-Mouse IgG. Blue - Mouse IgG Isotype Control Antibody (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: Recombinant CD19 Antibody (Ab219601)

Recombinant CD19 Antibody (Ab219601) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD19 (red) with Recombinant CD19 Antibody (Ab219601) at 0.5 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.