基本信息

产品名称	Obexelimab (anti-CD19), B 淋巴细胞抗原 CD19 抑制剂
别名	奥贝利单抗 \| 奥贝昔单抗（抗 CD19）
英文别名	Antibody deficiency due to defect in CD19 antibody \| Antibody deficiency due to defect in CD19, included antibody \| AW495831 antibody \| B lymphocyte antigen CD19 antibody \| B lymphocyte surface antigen B4 antibody \| B-lymphocyte antigen CD19 antibody \| B-
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属	人(Human)
特异性	CD19
种属反应性	人(Human),恒河猴(Rhesus monkey),食蟹猴(Cynomolgus monkey)
偶联	Unconjugated
作用类型	抑制剂
作用机制	B 淋巴细胞抗原 CD19 抑制剂

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG1
轻链亚型	kappa
SDS-PAGE	26.5 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 196.1 kDa, under non-reducing conditions.
纯化方法	Protein A purified
物理外观	Liquid
储存缓冲液	Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息	1690307-05-1
分子类型	抗体

关联靶点（人）

CD19 Tclin B淋巴细胞抗原CD19(B-lymphocyte antigen CD19) (0 活性数据)

点击查看靶蛋白信息： CD19

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Flow Cytometry: Obexelimab (anti-CD19) (Ab182851)

Obexelimab (anti-CD19) (Ab182851) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD19 with Obexelimab (anti-CD19) (Ab182851) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).

Flow Cytometry: Obexelimab (anti-CD19) (Ab182851)

Obexelimab (anti-CD19) (Ab182851) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD19 (red) with Obexelimab (anti-CD19) (Ab182851) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.