CXCR4/CD184 Mouse mAb (APC)

COA

级别和纯度:

已验证

ExactAb™

2 μL/test

应用:

Flow Cytometry

宿主种属: 小鼠(Mouse)
种属反应性: 人(Human)
亚型: Mouse IgG2a
克隆号: 12G5
偶联: APC

有货

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库存信息

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货号 (SKU)	包装规格	是否现货
Ab212891-10T	10T	现货
Ab212891-25T	25T	现货
Ab212891-100T	100T	现货

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基本信息

产品名称	CXCR4/CD184 Mouse mAb (APC)
别名	CXCR4/CD184抗体
英文别名	WHIM \| WHIMS1 \| D2S201E \| CD184 \| chemokine (C-X-C motif) receptor 4 \| chemokine (C-X-C motif), receptor 4 (fusin) \| C-X-C chemokine receptor type 4 \| CXCR4 \| CXC-R4 \| CXCR-4 \| D2S201ESDF-1 receptor \| FB22 \| Fusin \| HM89 \| HM89NPYRL \| HSY3RR \| LAP3 \| LAP-
规格或纯度	ExactAb™, 已验证, 2 μL/test
生化机理	Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus.
宿主种属	小鼠(Mouse)
特异性	CXCR4/CD184
种属反应性	人(Human)
阳性对照	Flow Cytometry: Jurkat
偶联	APC
Excitation(nm)	Red Laser(633nm)
Emission(nm)	660nm
Ex/Em(nm)	Ex:650nm;Em:660nm

产品属性

克隆类型	单克隆抗体
Format	Whole IgG
轻链亚型	kappa
纯化方法	Protein A/G purified
储存缓冲液	Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂	0.05% Proclin300
浓度	2 μL/test
储存温度	2-8°C储存,避光,禁止冷冻
运输条件	冰袋运输
稳定性与储存	The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
分子类型	抗体

关联靶点（人）

CXCR4 Tclin CXC 趋化因子受体 4 型(C-X-C chemokine receptor type 4) (0 活性数据)

点击查看靶蛋白信息： CXCR4

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: CXCR4/CD184 Mouse mAb (APC) (Ab212891)

CXCR4/CD184 Mouse mAb (APC) (Ab212891) - Flow Cytometry
Flow cytometry analysis of CXCR4/CD184 expression by Jurkat cells (red) compared to an isotype control (blue). Cells were stained with CXCR4/CD184 Mouse mAb (APC) (Ab212891) at 2μL/test for 1 hour at 4°C. Blue - Mouse IgG (APC) (Ab180309). Black - Unlabelled control, cells without incubation with primary antibody.

应用

应用名称	稀释比例
Flow Cytometry	2 μL/test For flow cytometric staining, the suggested use of this reagent is 2 µL per million cells in 100 µL staining volume or 2 µL per 100 µL of whole blood.