N Cadherin Mouse mAb

COA

级别和纯度:

≥95%(SDS-PAGE)
0.5 mg/mL

应用:

ELISA
WB

宿主种属: 小鼠(Mouse)
种属反应性: 人(Human)
亚型: Mouse IgG2b
克隆号: AB02/1F1
偶联: Unconjugated

有货

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货号 (SKU)	包装规格	是否现货
Ab183886-10μl	10μl	现货
Ab183886-50μl	50μL	现货
Ab183886-100μl	100μL	现货
Ab183886-1ml	1ml	期货

查看相关系列

点击查看靶蛋白信息: CDH2

Accession#: P19022 (7) CDH2 (7) Gene ID:1000 (7) N Cadherin (4)

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基本信息

产品名称	N Cadherin Mouse mAb
别名	N-钙粘蛋白 \| 神经钙黏蛋白 \| Anti-N Cadherin抗体 \| N Cadherin小鼠单克隆抗体 \| N Cadherin/CDH2 小鼠单克隆抗体 \| N Cadherin抗体
英文别名	CADH2_HUMAN antibody \| Cadherin 2 antibody \| Cadherin 2 N cadherin neuronal antibody \| Cadherin 2 type 1 antibody \| Cadherin 2 type 1 N cadherin neuronal antibody \| Cadherin 2, type 1, N-cadherin (neuronal) antibody \| Cadherin-2 antibody \| Cadherin2 antib
规格或纯度	无载体, ExactAb™, 已验证, 高性能, 无叠氮钠, ≥95%(SDS-PAGE), 0.5 mg/mL
生化机理	Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (By similarity). Required for proper neurite branching. Required for pre- and postsynaptic organization (By similarity). CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density
宿主种属	小鼠(Mouse)
特异性	N Cadherin
种属反应性	人(Human)
免疫原	Recombinant protein corresponding to Human N Cadherin
阳性对照	WB: HeLa, HEK293, SH-N-SH and SH-SY5Y whole cell lysates
偶联	Unconjugated

产品属性

克隆类型	单克隆抗体
Format	Whole IgG
轻链亚型	kappa
SDS-PAGE	150.0 KDa
纯化方法	Protein A purified
储存缓冲液	PBS, pH 7.2
浓度	0.5 mg/mL
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
分子类型	抗体

关联靶点（人）

CDH2 Tbio 钙粘蛋白-2(Cadherin-2) (0 活性数据)

点击查看靶蛋白信息： CDH2

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Western Blot: N Cadherin Mouse mAb (Ab183886)

N Cadherin Mouse mAb (Ab183886) - Western Blot
All lanes: N Cadherin Mouse Antibody (Ab183886) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution
Predicted band size: 100 kDa
Observed band size: 122 kDa
Exposure time: 15.0 s