基本信息

产品名称	Ravagalimab (anti-CD40), CD40 配体拮抗剂的拮抗剂
别名	拉瓦加利单抗（抗 CD40）
英文别名	AI326936 antibody \| B cell associated molecule CD40 antibody \| B cell surface antigen CD40 antibody \| B cell-associated molecule antibody \| B-cell surface antigen CD40 antibody \| Bp50 antibody \| CD 40 antibody \| CD40 antibody \| CD40 antigen (TNF receptor
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属	人(Human)
特异性	CD40
种属反应性	人(Human)
偶联	Unconjugated
作用类型	拮抗剂
作用机制	CD40 配体拮抗剂的拮抗剂

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG1
轻链亚型	kappa
SDS-PAGE	146.04 kDa
纯化方法	Protein A purified
物理外观	Liquid
储存缓冲液	Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息	2050816-56-1
分子类型	抗体

关联靶点（人）

CD40 Tchem 肿瘤坏死因子受体超家族成员 5(Tumor necrosis factor receptor superfamily member 5) (0 活性数据)

点击查看靶蛋白信息： CD40

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

CD40 Tchem Tumor necrosis factor receptor superfamily member 5 (9 活性数据)

点击查看靶蛋白信息： CD40

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Flow Cytometry: Ravagalimab (anti-CD40) (Ab182860)

Ravagalimab (anti-CD40) (Ab182860) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD40 with Ravagalimab (anti-CD40) (Ab182860) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).

ELISA: Ravagalimab (anti-CD40) (Ab182860)

Ravagalimab (anti-CD40) (Ab182860) - ELISA
Immobilized Recombinant Human CD40 protein (rp183577) at 1.0 μg/mL can bind Ravagalimab (anti-CD40) (Ab182860) with the EC50 of 11.32 ng/mL.

SEC: Ravagalimab (anti-CD40) (Ab182860)

Ravagalimab (anti-CD40) (Ab182860) - SEC
The purity of Ravagalimab (anti-CD40) (Ab182860) is more than 95% verified by HPLC.

Flow Cytometry: Ravagalimab (anti-CD40) (Ab182860)

Ravagalimab (anti-CD40) (Ab182860) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD40 (red) with Ravagalimab (anti-CD40) (Ab182860) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: Ravagalimab (anti-CD40) (Ab182860)

Ravagalimab (anti-CD40) (Ab182860) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD40 (red) with Ravagalimab (anti-CD40) (Ab182860). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: Ravagalimab (anti-CD40) (Ab182860)

Ravagalimab (anti-CD40) (Ab182860) - Flow Cytometry
Flow Cytometry analysis of Ramos cells labelling CD40 (red) with Ravagalimab (anti-CD40) (Ab182860). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.