货号 (SKU)

包装规格

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价格

数量

Ab177927-100μg

100μg

现货

Ab177927-1mg

1mg

现货

Ab177927-5mg

5mg

现货

Ab177927-10mg

10mg

期货

基本信息

产品名称	Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1)
别名	Asclepius Technology 专利抗Robo1 CAR(抗ROBO1)
英文别名	Deleted in U twenty twenty \| H-Robo-1
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属	人(Human)
特异性	ROBO1
种属反应性	人(Human)
偶联	Unconjugated

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG1
轻链亚型	kappa
SDS-PAGE	25.6 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 194.9 kDa, under non-reducing conditions.
纯化方法	Protein A purified
纯度	>95%
物理外观	Liquid
储存缓冲液	Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
分子类型	抗体

关联靶点（人）

ROBO1 Tbio 迂回同源物 1(Roundabout homolog 1) (0 活性数据)

点击查看靶蛋白信息： ROBO1

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927)

Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927) - Flow Cytometry
Flow Cytometry analysis of U2OS cells labelling ROBO1 (red) with Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927)

Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling ROBO1 (red) with Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927)

Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling ROBO1 (red) with Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

SEC: Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927)

Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927) - SEC
The purity of Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1) (Ab177927) is more than 95% verified by HPLC.

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找到6个结果

批号(Lot Number)	证书类型	货号
ZJ24F1114582	分析证书	Ab177927
ZJ24F1114583	分析证书	Ab177927
ZJ24F1114584	分析证书	Ab177927
ZJ24F0505087	分析证书	Ab177927
ZJ24F0505086	分析证书	Ab177927
ZJ24F0505085	分析证书	Ab177927

引用文献

1. Kidd, T T and 6 more authors.. (1998) Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors.. Cell, (23): [PMID:9458045]
2. Sundaresan, V V and 10 more authors.. (1998) The DUTT1 gene, a novel NCAM family member is expressed in developing murine neural tissues and has an unusually broad pattern of expression.. Molecular and cellular neurosciences, [PMID:9608531]
3. Sundaresan, V V and 18 more authors.. (1998) Homozygous deletions at 3p12 in breast and lung cancer.. Oncogene, (1): [PMID:9796701]
4. Brose, K K and 7 more authors.. (1999) Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.. Cell, (19): [PMID:10102268]
5. Bashaw, G J GJ, Kidd, T T, Murray, D D, Pawson, T T and Goodman, C S CS.. (2000) Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor.. Cell, (23): [PMID:10892742]
6. Nguyen Ba-Charvet, K T KT and 7 more authors.. (2001) Diversity and specificity of actions of Slit2 proteolytic fragments in axon guidance.. The Journal of neuroscience : the official journal of the Society for Neuroscience, (15): [PMID:11404413]
7. Dallol, Ashraf A and 9 more authors.. (2002) Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers.. Oncogene, (2): [PMID:12082532]
8. Muzny, Donna M DM and 113 more authors.. (2006) The DNA sequence, annotation and analysis of human chromosome 3.. Nature, (27): [PMID:16641997]
9. Morlot, Cecile C and 7 more authors.. (2007) Structural insights into the Slit-Robo complex.. Proceedings of the National Academy of Sciences of the United States of America, (18): [PMID:17848514]
10. Zakrys, Linas L and 5 more authors.. (2014) Roundabout 1 exists predominantly as a basal dimeric complex and this is unaffected by binding of the ligand Slit2.. The Biochemical journal, (1): [PMID:24673457]
11. Kong, Ruirui R and 13 more authors.. (2015) Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression.. The Journal of clinical investigation, (3): [PMID:26529257]

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Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1)

库存信息

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质检证书（CoA,COO,BSE/TSE 和分析图谱)

引用文献

溶液计算器

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Asclepius Technology patent anti-Robo1 CAR (anti-ROBO1)

库存信息

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关联靶点（人）

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质检证书（CoA,COO,BSE/TSE 和分析图谱)

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引用文献

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