货号 (SKU)

包装规格

是否现货

价格

数量

Ab177914-100μg

100μg

现货

Ab177914-1mg

1mg

现货

Ab177914-5mg

5mg

现货

Ab177914-10mg

10mg

期货

基本信息

产品名称	SAR428926 (anti-LAMP1)
别名	SAR428926（抗 LAMP1）
英文别名	CD107 antigen-like family member A \| LAMP-1 \| Lysosome-associated membrane protein 1
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属	人(Human)
特异性	LAMP1
种属反应性	人(Human),食蟹猴(Cynomolgus monkey)
偶联	Unconjugated

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG1
轻链亚型	kappa
SDS-PAGE	25.8 kDa (Light Chain) & 49.7kDa (Heavy Chain), under reducing conditions; 180.8 kDa, under non-reducing conditions.
纯化方法	Protein A purified
纯度	>95%
物理外观	Liquid
储存缓冲液	Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
分子类型	抗体

关联靶点（人）

LAMP1 Tbio 溶酶体相关膜糖蛋白 1(Lysosome-associated membrane glycoprotein 1) (0 活性数据)

点击查看靶蛋白信息： LAMP1

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: SAR428926 (anti-LAMP1) (Ab177914)

SAR428926 (anti-LAMP1) (Ab177914) - Flow Cytometry
Flow Cytometry analysis of U-2 OS cells labelling LAMP1 (red) with SAR428926 (anti-LAMP1) (Ab177914). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

SEC: SAR428926 (anti-LAMP1) (Ab177914)

SAR428926 (anti-LAMP1) (Ab177914) - SEC
The purity of SAR428926 (anti-LAMP1) (Ab177914) is more than 95% verified by HPLC.

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到6个结果

批号(Lot Number)	证书类型	货号
ZJ24F1114523	分析证书	Ab177914
ZJ24F1114522	分析证书	Ab177914
ZJ24F1114521	分析证书	Ab177914
ZJ24F0404066	分析证书	Ab177914
ZJ24F0404065	分析证书	Ab177914
ZJ24F0404064	分析证书	Ab177914

引用文献

1. Demirel Ö, Jan I, Wolters D, Blanz J, Saftig P, Tampé R, Abele R. (2012) The lysosomal polypeptide transporter TAPL is stabilized by interaction with LAMP-1 and LAMP-2.. J Cell Sci, 125 (Pt 18): (4230-40). [PMID:22641697]
2. Carlsson, S R SR and Fukuda, M M.. (1990) The polylactosaminoglycans of human lysosomal membrane glycoproteins lamp-1 and lamp-2. Localization on the peptide backbones.. The Journal of biological chemistry, (25): [PMID:2243102]
3. Carlsson, S R SR and Fukuda, M M.. (1989) Structure of human lysosomal membrane glycoprotein 1. Assignment of disulfide bonds and visualization of its domain arrangement.. The Journal of biological chemistry, (5): [PMID:2584229]
4. Mane, S M SM and 6 more authors.. (1989) Purification and characterization of human lysosomal membrane glycoproteins.. Archives of biochemistry and biophysics, [PMID:2912382]
5. Viitala, J J, Carlsson, S R SR, Siebert, P D PD and Fukuda, M M.. (1988) Molecular cloning of cDNAs encoding lamp A, a human lysosomal membrane glycoprotein with apparent Mr approximately equal to 120,000.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:3131762]
6. Fukuda, M M, Viitala, J J, Matteson, J J and Carlsson, S R SR.. (1988) Cloning of cDNAs encoding human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Comparison of their deduced amino acid sequences.. The Journal of biological chemistry, (15): [PMID:3198605]
7. Carlsson, S R SR, Lycksell, P O PO and Fukuda, M M.. (1993) Assignment of O-glycan attachment sites to the hinge-like regions of human lysosomal membrane glycoproteins lamp-1 and lamp-2.. Archives of biochemistry and biophysics, [PMID:8323299]
8. Sawada, R R, Jardine, K A KA and Fukuda, M M.. (1993) The genes of major lysosomal membrane glycoproteins, lamp-1 and lamp-2. 5'-flanking sequence of lamp-2 gene and comparison of exon organization in two genes.. The Journal of biological chemistry, (25): [PMID:8517882]
9. Zhang, Hui H, Li, Xiao-Jun XJ, Martin, Daniel B DB and Aebersold, Ruedi R.. (2003) Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.. Nature biotechnology, [PMID:12754519]
10. Dunham, A A and 125 more authors.. (2004) The DNA sequence and analysis of human chromosome 13.. Nature, (1): [PMID:15057823]
11. Johansson, Marie M, Lehto, Markku M, Tanhuanpää, Kimmo K, Cover, Timothy L TL and Olkkonen, Vesa M VM.. (2005) The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments.. Molecular biology of the cell, [PMID:16176980]
12. Schröder, Bernd B and 8 more authors.. (2007) Integral and associated lysosomal membrane proteins.. Traffic (Copenhagen, Denmark), [PMID:17897319]
13. Krzewski, Konrad K, Gil-Krzewska, Aleksandra A, Nguyen, Victoria V, Peruzzi, Giovanna G and Coligan, John E JE.. (2013) LAMP1/CD107a is required for efficient perforin delivery to lytic granules and NK-cell cytotoxicity.. Blood, (6): [PMID:23632890]
14. Cohnen, André A and 9 more authors.. (2013) Surface CD107a/LAMP-1 protects natural killer cells from degranulation-associated damage.. Blood, (22): [PMID:23847195]
15. Tuli, Amit A and 9 more authors.. (2013) Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell-mediated cytotoxicity.. Molecular biology of the cell, [PMID:24088571]
16. Jae, Lucas T LT and 12 more authors.. (2014) Virus entry. Lassa virus entry requires a trigger-induced receptor switch.. Science (New York, N.Y.), (27): [PMID:24970085]
17. Cohen-Dvashi, Hadas H, Cohen, Nadav N, Israeli, Hadar H and Diskin, Ron R.. (2015) Molecular Mechanism for LAMP1 Recognition by Lassa Virus.. Journal of virology, [PMID:25972533]
18. Cohen-Dvashi, Hadas H, Israeli, Hadar H, Shani, Orly O, Katz, Aliza A and Diskin, Ron R.. (2016) Role of LAMP1 Binding and pH Sensing by the Spike Complex of Lassa Virus.. Journal of virology, (15): [PMID:27605678]
19. Hulseberg, Christine E CE, Fénéant, Lucie L, Szymańska, Katarzyna M KM and White, Judith M JM.. (2018) Lamp1 Increases the Efficiency of Lassa Virus Infection by Promoting Fusion in Less Acidic Endosomal Compartments.. mBio, (2): [PMID:29295909]
20. Ueo, Ayako and 5 more authors.. (2020) Lysosome-Associated Membrane Proteins Support the Furin-Mediated Processing of the Mumps Virus Fusion Protein.. Journal of virology, (1): [PMID:32295904]

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SAR428926 (anti-LAMP1)

库存信息

库存信息

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基本信息

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关联靶点（人）

图片

质检证书（CoA,COO,BSE/TSE 和分析图谱)

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

SAR428926 (anti-LAMP1)

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

图片

质检证书（CoA,COO,BSE/TSE 和分析图谱)

相关产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器