首页
小分子和化合物库
抗体类配体
Lacutamab (anti-KIR3DL2), 杀伤细胞免疫球蛋白样受体 3DL2 拮抗剂

Lacutamab (anti-KIR3DL2), 杀伤细胞免疫球蛋白样受体 3DL2 拮抗剂

级别和纯度:

≥95%(SDS-PAGE&SEC-HPLC)
见COA

应用:

Animal Model
ELISA
Flow Cytometry
Functional Assay

宿主种属: 人(Human)
种属反应性: 人(Human), 兔(Rabbit), 小鼠(Mouse)
亚型: Human IgG1
偶联: Unconjugated

有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货
Ab177905-100μg	100μg	现货
Ab177905-1mg	1mg	现货
Ab177905-5mg	5mg	现货
Ab177905-10mg	10mg	期货

查看相关系列

点击查看靶蛋白信息: KIR3DL3 点击查看靶蛋白信息: KIR3DL2

Accession#:P43630 (2) Gene ID:3812 (2) KIR3DL2 (2)

Skip to the end of the images gallery

Skip to the beginning of the images gallery

基本信息

产品名称	Lacutamab (anti-KIR3DL2), 杀伤细胞免疫球蛋白样受体 3DL2 拮抗剂
别名	拉库他单抗（抗 KIR3DL2）
英文别名	CD158 antigen-like family member K \| MHC class I NK cell receptor \| Natural killer-associated transcript 4 \| NKAT-4 \| p70 natural killer cell receptor clone CL-5 \| p70 NK receptor CL-5
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属	人(Human)
特异性	KIR3DL2
种属反应性	人(Human),兔(Rabbit),小鼠(Mouse)
偶联	Unconjugated
作用类型	拮抗剂
作用机制	杀伤细胞免疫球蛋白样受体 3DL2 拮抗剂

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG1
轻链亚型	kappa
SDS-PAGE	26.4 kDa (Light Chain) & 51.1 kDa (Heavy Chain), under reducing conditions; 178.3 kDa, under non-reducing conditions.
纯化方法	Protein A purified
纯度	>95%
物理外观	Liquid
储存缓冲液	Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息	2187368-16-5
分子类型	抗体

关联靶点（人）

KIR3DL3 Tbio 杀伤细胞免疫球蛋白类受体 3DL3(Killer cell immunoglobulin-like receptor 3DL3) (0 活性数据)

点击查看靶蛋白信息： KIR3DL3

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

KIR3DL2 Tbio 杀伤细胞免疫球蛋白类受体 3DL2(Killer cell immunoglobulin-like receptor 3DL2) (0 活性数据)

点击查看靶蛋白信息： KIR3DL2

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Flow Cytometry: Lacutamab (anti-KIR3DL2) (Ab177905)

Lacutamab (anti-KIR3DL2) (Ab177905) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling KIR3DL2 with Lacutamab (anti-KIR3DL2) (Ab177905) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Flow Cytometry: Lacutamab (anti-KIR3DL2) (Ab177905)

Lacutamab (anti-KIR3DL2) (Ab177905) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling KIR3DL2 (red) with Lacutamab (anti-KIR3DL2) (Ab177905) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

SEC: Lacutamab (anti-KIR3DL2) (Ab177905)

Lacutamab (anti-KIR3DL2) (Ab177905) - SEC
The purity of Lacutamab (anti-KIR3DL2) (Ab177905) is more than 95% verified by HPLC.

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到3个结果

批号(Lot Number)	证书类型	货号
ZJ24F0404113	分析证书	Ab177905
ZJ24F0404114	分析证书	Ab177905
ZJ24F0404115	分析证书	Ab177905

引用文献

1. Colonna M, Samaridis J. (1995) Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.. Science, 268 (5209): (405-8). [PMID:7716543]
2. Döhring C, Samaridis J, Colonna M. (1996) Alternatively spliced forms of human killer inhibitory receptors.. Immunogenetics, 44 (3): (227-30). [PMID:8662091]
3. Pende, D D and 9 more authors.. (1996) The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.. The Journal of experimental medicine, (1): [PMID:8760804]
4. Wagtmann, N N, Rajagopalan, S S, Winter, C C CC, Peruzzi, M M and Long, E O EO.. (1995) Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer.. Immunity, [PMID:8777725]
5. Uhrberg, M M and 8 more authors.. (1997) Human diversity in killer cell inhibitory receptor genes.. Immunity, [PMID:9430221]
6. Goodridge, Jodie P JP, Burian, Aura A, Lee, Ni N and Geraghty, Daniel E DE.. (2013) HLA-F and MHC class I open conformers are ligands for NK cell Ig-like receptors.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:24018270]
7. Song, SungWon S and 11 more authors.. (2016) Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis.. Nature medicine, [PMID:26928464]
8. Dulberger, Charles L CL and 12 more authors.. (2017) Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors.. Immunity, (20): [PMID:28636952]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

体积

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)

浓度 2 (C2)

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度

Lacutamab (anti-KIR3DL2), 杀伤细胞免疫球蛋白样受体 3DL2 拮抗剂

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

质检证书（CoA,COO,BSE/TSE 和分析图谱)

相关产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器