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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab177868-100μg |
100μg |
现货 ![]() |
| |
| Ab177868-1mg |
1mg |
现货 ![]() |
| |
| Ab177868-5mg |
5mg |
现货 ![]() |
| |
| Ab177868-10mg |
10mg |
期货 ![]() |
|
| 产品名称 | RO5458640 (anti-TNFSF12) |
|---|---|
| 别名 | APO 3 ligand antibody | APO 3L antibody | APO3 ligand antibody | APO3/DR3 ligand antibody | APO3L antibody | DR3LG antibody | MGC129581 antibody | MGC20669 antibody | secreted form antibody | TNF-related weak inducer of apoptosis antibody | TNF12_HUMAN an |
| 英文别名 | APO3 ligand | TNF-related weak inducer of apoptosis | TWEAK |
| 规格或纯度 | 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA |
| 宿主种属 | 人(Human) |
| 特异性 | TNFSF12 |
| 种属反应性 | 人(Human) |
| 偶联 | Unconjugated |
| 克隆类型 | 重组抗体 |
|---|---|
| Format | Whole IgG |
| 亚型 | Human IgG1 |
| 轻链亚型 | kappa |
| SDS-PAGE | 26.4 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 189.7 kDa, under non-reducing conditions. |
| 纯化方法 | Protein A purified |
| 纯度 | >95% |
| 物理外观 | Liquid |
| 储存缓冲液 | Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | -80℃储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。 |
| 分子类型 | 抗体 |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
RO5458640 (anti-TNFSF12) (Ab177868) - SEC
The purity of RO5458640 (anti-TNFSF12) (Ab177868) is more than 95% verified by HPLC.
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab177868 | |
| 分析证书 | Ab177868 | |
| 分析证书 | Ab177868 | |
| 分析证书 | Ab177868 |
| 1. Marsters, S A SA and 5 more authors.. (1998) Identification of a ligand for the death-domain-containing receptor Apo3.. Current biology : CB, (23): [PMID:9560343] |
| 2. Pradet-Balade, B B and 8 more authors.. (2002) An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion protein.. The EMBO journal, (1): [PMID:12411489] |
| 3. Wiley, Steven R SR and Winkles, Jeffrey A JA.. TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor.. Cytokine & growth factor reviews, [PMID:12787562] |
| 4. Tian, Xiao-Li XL and 14 more authors.. (2004) Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome.. Nature, (12): [PMID:14961121] |
| 5. Lammens, Alfred A and 7 more authors.. (2013) Crystal structure of human TWEAK in complex with the Fab fragment of a neutralizing antibody reveals insights into receptor binding.. PloS one, [PMID:23667509] |