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IL-12 p70 Mouse mAb

    应用:
  • Capture Antibody
  • ELISA
  • FIA
  • FLFIA
  • 宿主种属: 小鼠(Mouse)
  • 种属反应性: 人(Human)
  • 亚型: Mouse IgG1
  • 克隆号: 6G10-2
  • 偶联: Unconjugated
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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
Ab176577-10μg
10μg 现货 Stock Image
Ab176577-50μg
50μg 现货 Stock Image
Ab176577-100μg
100μg 期货 Stock Image
Ab176577-1mg
1mg 期货 Stock Image

基本信息

产品名称 IL-12 p70 Mouse mAb
别名 抗IL-12 p70抗体 | IL-12 p70 小鼠单克隆抗体 | IL-12 p70 小鼠单抗
英文别名 CLMF p35 | Cytotoxic lymphocyte maturation factor 35 kDa subunit | IL12 p70 | IL-12 p70 | IL-12 subunit p35 | IL-12, subunit p35 | interleukin 12, p35 | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocytematuration factor 1, p3
规格或纯度 无载体, ExactAb™, 无叠氮钠, 已验证, 见COA
宿主种属 小鼠(Mouse)
特异性 IL12A; IL12B
种属反应性 人(Human)
免疫原 Recombinant Human IL-12 Protein
偶联 Unconjugated

产品属性

克隆类型 单克隆抗体
克隆号 6G10-2
Format Whole IgG
亚型 Mouse IgG1
轻链亚型 kappa
SDS-PAGE 150 kDa
纯化方法 Affinity chromatography
配对抗体 [Ab176579] IL-12 p70 Mouse mAb as Detection antibody in ELISA, FIA
物理外观 Liquid
储存缓冲液 10mM PBS, pH7.4
防腐剂 No
浓度 见COA
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 37°C 下短期保存(7 天) 4°C 下短期保存(30 天)。在 -20±5°C 下长期储存(36 个月)。收货后建议分装。避免冷冻/解冻循环。
分子类型 抗体

关联靶点(人)

IL12A Tclin 白细胞介素-12 亚基 α(Interleukin-12 subunit alpha) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
IL12B Tclin 白细胞介素-12亚基β(Interleukin-12 subunit beta) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
IL12B Tclin Interleukin-12 (0 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
IL12B Tclin Interleukin-23 (0 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

图片

Relevance of detection results between aladdin Antibody Pair (Ab176577 & Ab176579/Ab176581) in CLIA
Capture antibody: IL-12 p70 Mouse mAb (Ab176577)
Detection antibody: IL-12 p70 Mouse mAb (Ab176579)
Linear Range: 0.1 - 2000 pg/mL

Capture antibody: IL-12 p70 Mouse mAb (Ab176577)
Detection antibody: IL-12 p70 Mouse mAb (Ab176581)
Linear Range: 0.1 - 2000 pg/mL

应用

应用名称 稀释比例
FLFIA

Fluorescent beads/Antibody =10/1

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

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找到3个结果

批号(Lot Number) 证书类型 货号
ZJ24F0607339 分析证书 Ab176577
ZJ24F0607338 分析证书 Ab176577
ZJ24F0607337 分析证书 Ab176577

引用文献

1. Wolf SF, Temple PA, Kobayashi M, Young D, Dicig M, Lowe L, Dzialo R, Fitz L, Ferenz C, Hewick RM et al..  (1991)  Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells..  J Immunol,  146  (9): (3074-81).  [PMID:1673147]
2. Gubler, U U and 9 more authors..  (1991)  Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor..  Proceedings of the National Academy of Sciences of the United States of America,  (15): [PMID:1674604]
3. Stern, A S AS and 9 more authors..  (1990)  Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells..  Proceedings of the National Academy of Sciences of the United States of America,  [PMID:2204066]
4. Bacon, C M CM and 5 more authors..  (1995)  Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12..  The Journal of experimental medicine,  (1): [PMID:7528775]
5. Bacon, C M CM and 6 more authors..  (1995)  Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes..  Proceedings of the National Academy of Sciences of the United States of America,  (1): [PMID:7638186]
6. Presky, D H DH and 7 more authors..  (1996)  A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits..  Proceedings of the National Academy of Sciences of the United States of America,  (26): [PMID:8943050]
7. Devergne, O O, Birkenbach, M M and Kieff, E E..  (1997)  Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin..  Proceedings of the National Academy of Sciences of the United States of America,  (28): [PMID:9342359]
8. Yoon, C C and 5 more authors..  (2000)  Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12..  The EMBO journal,  (17): [PMID:10899108]
9. Leong, Wai Fook WF and Chow, Vincent T K VT..  (2006)  Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection..  Cellular microbiology,  [PMID:16548883]
10. Muzny, Donna M DM and 113 more authors..  (2006)  The DNA sequence, annotation and analysis of human chromosome 3..  Nature,  (27): [PMID:16641997]
11. Collison, Lauren W and 11 more authors..  (2012)  The composition and signaling of the IL-35 receptor are unconventional..  Nature immunology,  (5): [PMID:22306691]

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