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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab176577-10μg |
10μg |
现货 ![]() |
| |
| Ab176577-50μg |
50μg |
现货 ![]() |
| |
| Ab176577-100μg |
100μg |
期货 ![]() |
| |
| Ab176577-1mg |
1mg |
期货 ![]() |
|
| 产品名称 | IL-12 p70 Mouse mAb |
|---|---|
| 别名 | 抗IL-12 p70抗体 | IL-12 p70 小鼠单克隆抗体 | IL-12 p70 小鼠单抗 |
| 英文别名 | CLMF p35 | Cytotoxic lymphocyte maturation factor 35 kDa subunit | IL12 p70 | IL-12 p70 | IL-12 subunit p35 | IL-12, subunit p35 | interleukin 12, p35 | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocytematuration factor 1, p3 |
| 规格或纯度 | 无载体, ExactAb™, 无叠氮钠, 已验证, 见COA |
| 宿主种属 | 小鼠(Mouse) |
| 特异性 | IL12A; IL12B |
| 种属反应性 | 人(Human) |
| 免疫原 | Recombinant Human IL-12 Protein |
| 偶联 | Unconjugated |
| 克隆类型 | 单克隆抗体 |
|---|---|
| 克隆号 | 6G10-2 |
| Format | Whole IgG |
| 亚型 | Mouse IgG1 |
| 轻链亚型 | kappa |
| SDS-PAGE | 150 kDa |
| 纯化方法 | Affinity chromatography |
| 配对抗体 | [Ab176579] IL-12 p70 Mouse mAb as Detection antibody in ELISA, FIA |
| 物理外观 | Liquid |
| 储存缓冲液 | 10mM PBS, pH7.4 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 37°C 下短期保存(7 天) 4°C 下短期保存(30 天)。在 -20±5°C 下长期储存(36 个月)。收货后建议分装。避免冷冻/解冻循环。 |
| 分子类型 | 抗体 |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
Relevance of detection results between aladdin Antibody Pair (Ab176577 & Ab176579/Ab176581) in CLIA
Capture antibody: IL-12 p70 Mouse mAb (Ab176577)
Detection antibody: IL-12 p70 Mouse mAb (Ab176579)
Linear Range: 0.1 - 2000 pg/mL
Capture antibody: IL-12 p70 Mouse mAb (Ab176577)
Detection antibody: IL-12 p70 Mouse mAb (Ab176581)
Linear Range: 0.1 - 2000 pg/mL
| 应用名称 | 稀释比例 |
|---|---|
| FLFIA | Fluorescent beads/Antibody =10/1 |
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab176577 | |
| 分析证书 | Ab176577 | |
| 分析证书 | Ab176577 |
¥499.90
¥499.90
| 1. Wolf SF, Temple PA, Kobayashi M, Young D, Dicig M, Lowe L, Dzialo R, Fitz L, Ferenz C, Hewick RM et al.. (1991) Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells.. J Immunol, 146 (9): (3074-81). [PMID:1673147] |
| 2. Gubler, U U and 9 more authors.. (1991) Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor.. Proceedings of the National Academy of Sciences of the United States of America, (15): [PMID:1674604] |
| 3. Stern, A S AS and 9 more authors.. (1990) Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2204066] |
| 4. Bacon, C M CM and 5 more authors.. (1995) Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12.. The Journal of experimental medicine, (1): [PMID:7528775] |
| 5. Bacon, C M CM and 6 more authors.. (1995) Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes.. Proceedings of the National Academy of Sciences of the United States of America, (1): [PMID:7638186] |
| 6. Presky, D H DH and 7 more authors.. (1996) A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits.. Proceedings of the National Academy of Sciences of the United States of America, (26): [PMID:8943050] |
| 7. Devergne, O O, Birkenbach, M M and Kieff, E E.. (1997) Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin.. Proceedings of the National Academy of Sciences of the United States of America, (28): [PMID:9342359] |
| 8. Yoon, C C and 5 more authors.. (2000) Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12.. The EMBO journal, (17): [PMID:10899108] |
| 9. Leong, Wai Fook WF and Chow, Vincent T K VT.. (2006) Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.. Cellular microbiology, [PMID:16548883] |
| 10. Muzny, Donna M DM and 113 more authors.. (2006) The DNA sequence, annotation and analysis of human chromosome 3.. Nature, (27): [PMID:16641997] |
| 11. Collison, Lauren W and 11 more authors.. (2012) The composition and signaling of the IL-35 receptor are unconventional.. Nature immunology, (5): [PMID:22306691] |