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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab176453-100μg |
100μg |
现货 ![]() |
| |
| Ab176453-1mg |
1mg |
现货 ![]() |
| |
| Ab176453-5mg |
5mg |
现货 ![]() |
| |
| Ab176453-10mg |
10mg |
期货 ![]() |
|
| 产品名称 | Roledumab (anti-RHD), 血型 Rh(D)多肽抑制剂 |
|---|---|
| 别名 | 罗来度单抗 | 罗地单抗(抗 RHD) |
| 英文别名 | Blood group Rh(D) polypeptide antibody | Blood group--Rhesus system D polypeptide antibody | CD240D antibody | D antigen (DCS) antibody | DIIIc antibody | MGC165007 antibody | RH antibody | Rh blood group antigen Evans antibody | Rh blood group D antigen |
| 规格或纯度 | 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA |
| 宿主种属 | 人(Human) |
| 特异性 | RHD |
| 种属反应性 | 人(Human),恒河猴(Rhesus monkey) |
| 偶联 | Unconjugated |
| 作用类型 | 抑制剂 |
| 作用机制 | 血型 Rh(D)多肽抑制剂 |
| 克隆类型 | 重组抗体 |
|---|---|
| Format | Whole IgG |
| 亚型 | Human IgG1 |
| 轻链亚型 | kappa |
| SDS-PAGE | 26.4 kDa (Light Chain) & 51.4 kDa (Heavy Chain), under reducing conditions; 174.1 kDa, under non-reducing conditions. |
| 纯化方法 | Protein A purified |
| 纯度 | >95% |
| 物理外观 | Liquid |
| 储存缓冲液 | Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | -80℃储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。 |
| CAS编号和信息 | 1174008-79-7 |
| 分子类型 | 抗体 |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
Roledumab (anti-RHD) (Ab176453) - SEC
The purity of Roledumab (anti-RHD) (Ab176453) is more than 95% verified by HPLC.
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab176453 | |
| 分析证书 | Ab176453 | |
| 分析证书 | Ab176453 |
¥669.90
| 1. Le Van Kim, C C and 6 more authors.. (1992) Multiple Rh messenger RNA isoforms are produced by alternative splicing.. Blood, (15): [PMID:1379850] |
| 2. Le van Kim, C C and 6 more authors.. (1992) Molecular cloning and primary structure of the human blood group RhD polypeptide.. Proceedings of the National Academy of Sciences of the United States of America, (15): [PMID:1438298] |
| 3. Colin, Y Y and 5 more authors.. (1991) Genetic basis of the RhD-positive and RhD-negative blood group polymorphism as determined by Southern analysis.. Blood, (15): [PMID:1824267] |
| 4. Suyama, K K, Goldstein, J J, Aebersold, R R and Kent, S S.. (1991) Regarding the size of Rh proteins.. Blood, (15): [PMID:1898705] |
| 5. Saboori, A M AM, Smith, B L BL and Agre, P P.. (1988) Polymorphism in the Mr 32,000 Rh protein purified from Rh(D)-positive and -negative erythrocytes.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:3131772] |
| 6. Bloy, C C and 5 more authors.. (1988) Determination of the N-terminal sequence of human red cell Rh(D) polypeptide and demonstration that the Rh(D), (c), and (E) antigens are carried by distinct polypeptide chains.. Blood, [PMID:3135863] |
| 7. Avent, N D ND and 5 more authors.. (1988) Protein-sequence studies on Rh-related polypeptides suggest the presence of at least two groups of proteins which associate in the human red-cell membrane.. The Biochemical journal, (15): [PMID:3146980] |
| 8. Huang, C H CH, Reid, M E ME and Chen, Y Y.. (1995) Identification of a partial internal deletion in the RH locus causing the human erythrocyte D--phenotype.. Blood, (15): [PMID:7606008] |
| 9. Rouillac, C C, Le Van Kim, C C, Beolet, M M, Cartron, J P JP and Colin, Y Y.. (1995) Leu110Pro substitution in the RhD polypeptide is responsible for the DVII category blood group phenotype.. American journal of hematology, [PMID:7741145] |
| 10. Kajii, E E, Umenishi, F F, Iwamoto, S S and Ikemoto, S S.. (1993) Isolation of a new cDNA clone encoding an Rh polypeptide associated with the Rh blood group system.. Human genetics, [PMID:7916743] |
| 11. Suyama, K K, Lunn, R R, Haller, S S and Goldstein, J J.. (1994) Rh(D) antigen expression and isolation of a new Rh(D) cDNA isoform in human erythroleukemic K562 cells.. Blood, (15): [PMID:8080999] |
| 12. Westhoff, C M CM and Wylie, D E DE.. (1994) Identification of a new RhD-specific mRNA from K562 cells.. Blood, (15): [PMID:8180407] |
| 13. Arce, M A MA and 5 more authors.. (1993) Molecular cloning of RhD cDNA derived from a gene present in RhD-positive, but not RhD-negative individuals.. Blood, (15): [PMID:8329718] |
| 14. Wagner, F F FF and 5 more authors.. (1999) Molecular basis of weak D phenotypes.. Blood, (1): [PMID:9864185] |
| 15. Urbaniak, S J SJ and Greiss, M A MA.. (2000) RhD haemolytic disease of the fetus and the newborn.. Blood reviews, [PMID:10805260] |
| 16. Wagner, F F FF and Flegel, W A WA.. (2000) RHD gene deletion occurred in the Rhesus box.. Blood, (15): [PMID:10845894] |
| 17. Shao, Chao-Peng CP, Xiong, Wen W and Zhou, Yi-Yan YY.. (2006) Multiple isoforms excluding normal RhD mRNA detected in Rh blood group Del phenotype with RHD 1227A allele.. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, [PMID:16510313] |