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KWAR23 (anti-SIRPg)

    应用:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • 宿主种属: 人(Human)
  • 种属反应性: 人(Human), 小鼠(Mouse), 恒河猴(Rhesus monkey), 食蟹猴(Cynomolgus monkey)
  • 亚型: Human IgG4SP
  • 偶联: Unconjugated
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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
Ab176451-100μg
100μg 现货 Stock Image
Ab176451-1mg
1mg 现货 Stock Image
Ab176451-5mg
5mg 现货 Stock Image
Ab176451-10mg
10mg 期货 Stock Image

基本信息

产品名称 KWAR23 (anti-SIRPg)
别名 CD172 antigen like family member B antibody | bA77C3.1 antibody | CD172 antigen-like family member B antibody | CD172g antibody | CD172g antigen antibody | FLJ42230 antibody | RP11-77C3.2 antibody | Signal regulatory protein beta 2 antibody | Signal regul
英文别名 CD172 antigen-like family member B | Signal-regulatory protein beta-2 | SIRP-b2 | SIRP-beta-2 | SIRP-gamma
规格或纯度 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属 人(Human)
特异性 SIRPG
种属反应性 人(Human),小鼠(Mouse),恒河猴(Rhesus monkey),食蟹猴(Cynomolgus monkey)
偶联 Unconjugated
作用类型 抑制剂

产品属性

克隆类型 重组抗体
Format Whole IgG
亚型 Human IgG4SP
轻链亚型 kappa
SDS-PAGE 26.8 kDa (Light Chain) & 51.9 kDa (Heavy Chain), under reducing conditions; 169.3 kDa, under non-reducing conditions.
纯化方法 Protein A purified
纯度 >95%
物理外观 Liquid
储存缓冲液 Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂 No
浓度 见COA
储存温度 -80℃储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息 2243227-60-1
分子类型 抗体

关联靶点(人)

SIRPG Tbio 信号调节蛋白γ(Signal-regulatory protein gamma) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

图片

KWAR23 (anti-SIRPg) (Ab176451) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling SIRPg (red) with KWAR23 (anti-SIRPg) (Ab176451). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

KWAR23 (anti-SIRPg) (Ab176451) - SEC
The purity of KWAR23 (anti-SIRPg) (Ab176451) is more than 95% verified by HPLC.

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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找到5个结果

批号(Lot Number) 证书类型 货号
ZJ23F1101611 分析证书 Ab176451
ZJ23F1101610 分析证书 Ab176451
ZJ24F0911529 分析证书 Ab176451
ZJ24F0911530 分析证书 Ab176451
ZJ24F0911531 分析证书 Ab176451

引用文献

1. Ichigotani, Y Y and 7 more authors..  (2000)  Molecular cloning of a novel human gene (SIRP-B2) which encodes a new member of the SIRP/SHPS-1 protein family..  Journal of human genetics,  [PMID:11185750]
2. Piccio, Laura L and 7 more authors..  (2005)  Adhesion of human T cells to antigen-presenting cells through SIRPbeta2-CD47 interaction costimulates T-cell proliferation..  Blood,  (15): [PMID:15383453]
3. Hatherley, Deborah D and 5 more authors..  (2008)  Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47..  Molecular cell,  (25): [PMID:18657508]
4. Wollscheid, Bernd B and 7 more authors..  (2009)  Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins..  Nature biotechnology,  [PMID:19349973]

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