货号 (SKU)

包装规格

是否现货

价格

数量

Ab176222-100μg

100μg

现货

Ab176222-1mg

1mg

现货

Ab176222-5mg

5mg

现货

Ab176222-10mg

10mg

期货

基本信息

产品名称	Tusamitamab (anti-CEACAM5)
别名	特赛妥单抗 \| 妥沙米单抗（抗 CEACAM5）
英文别名	Carcinoembryonic antigen antibody \| Carcinoembryonic antigen-related cell adhesion molecule 5 antibody \| CD66e antibody \| CEA antibody \| Ceacam5 antibody \| CEAM5_HUMAN antibody \| DKFZp781M2392 antibody \| Meconium antigen 100 antibody \| OTTHUMP00000199032
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属	人(Human)
特异性	CEACAM5
种属反应性	人(Human),食蟹猴(Cynomolgus monkey)
偶联	Unconjugated

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG1
轻链亚型	kappa
SDS-PAGE	26.6 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 172.9 kDa, under non-reducing conditions.
纯化方法	Protein A purified
纯度	>95%
物理外观	Liquid
储存缓冲液	Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息	2349294-95-5
分子类型	抗体

关联靶点（人）

CEACAM5 Tbio 癌胚抗原相关细胞粘附分子5(Carcinoembryonic antigen-related cell adhesion molecule 5) (0 活性数据)

点击查看靶蛋白信息： CEACAM5

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

ELISA: Tusamitamab (anti-CEACAM5) (Ab176222)

Tusamitamab (anti-CEACAM5) (Ab176222) - ELISA
Immobilized hu-CEACAM5-His at 2 μg/mL can bind Tusamitamab (anti-CEACAM5) (Ab176222) with the EC₅₀ of 4.02 ng/mL.

SEC: Tusamitamab (anti-CEACAM5) (Ab176222)

Tusamitamab (anti-CEACAM5) (Ab176222) - SEC
The purity of Tusamitamab (anti-CEACAM5) (Ab176222) is more than 95% verified by HPLC.

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到3个结果

批号(Lot Number)	证书类型	货号
ZJ24F0303027	分析证书	Ab176222
ZJ24F0303026	分析证书	Ab176222
ZJ24F0303025	分析证书	Ab176222

可替换产品

引用文献

1. Hefta, L J LJ and 5 more authors.. (1990) Expression of complementary DNA and genomic clones for carcinoembryonic antigen and nonspecific cross-reacting antigen in Chinese hamster ovary and mouse fibroblast cells and characterization of the membrane-expressed products.. Cancer research, (15): [PMID:2317824]
2. Schrewe, H H and 8 more authors.. (1990) Cloning of the complete gene for carcinoembryonic antigen: analysis of its promoter indicates a region conveying cell type-specific expression.. Molecular and cellular biology, [PMID:2342461]
3. Oikawa, S S and 5 more authors.. (1989) Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion.. Biochemical and biophysical research communications, (16): [PMID:2803308]
4. Zimmermann, W W, Ortlieb, B B, Friedrich, R R and von Kleist, S S.. (1987) Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:3033671]
5. Barnett, T T, Goebel, S J SJ, Nothdurft, M A MA and Elting, J J JJ.. (1988) Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains.. Genomics, [PMID:3220478]
6. Beauchemin, N N, Benchimol, S S, Cournoyer, D D, Fuks, A A and Stanners, C P CP.. (1987) Isolation and characterization of full-length functional cDNA clones for human carcinoembryonic antigen.. Molecular and cellular biology, [PMID:3670312]
7. Oikawa, S S, Nakazato, H H and Kosaki, G G.. (1987) Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence.. Biochemical and biophysical research communications, (30): [PMID:3814146]
8. Frängsmyr, L L, Baranov, V V and Hammarström, S S.. Four carcinoembryonic antigen subfamily members, CEA, NCA, BGP and CGM2, selectively expressed in the normal human colonic epithelium, are integral components of the fuzzy coat.. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, [PMID:10436421]
9. Boehm, M K MK and Perkins, S J SJ.. (2000) Structural models for carcinoembryonic antigen and its complex with the single-chain Fv antibody molecule MFE23.. FEBS letters, (9): [PMID:10854848]
10. Taheri, M M and 5 more authors.. (2000) Self recognition in the Ig superfamily. Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion.. The Journal of biological chemistry, (1): [PMID:10864933]
11. Ordoñez, C C, Screaton, R A RA, Ilantzis, C C and Stanners, C P CP.. (2000) Human carcinoembryonic antigen functions as a general inhibitor of anoikis.. Cancer research, (1): [PMID:10910050]
12. Ramachandran, Prasanna P and 5 more authors.. (2006) Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.. Journal of proteome research, [PMID:16740002]
13. Korotkova, Natalia N and 9 more authors.. (2008) Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation.. Molecular microbiology, [PMID:18086185]
14. Govindan, Serengulam V SV, Cardillo, Thomas M TM, Moon, Sung-Ju SJ, Hansen, Hans J HJ and Goldenberg, David M DM.. (2009) CEACAM5-targeted therapy of human colonic and pancreatic cancer xenografts with potent labetuzumab-SN-38 immunoconjugates.. Clinical cancer research : an official journal of the American Association for Cancer Research, (1): [PMID:19789330]
15. Bonsor, Daniel A DA, Günther, Sebastian S, Beadenkopf, Robert R, Beckett, Dorothy D and Sundberg, Eric J EJ.. (2015) Diverse oligomeric states of CEACAM IgV domains.. Proceedings of the National Academy of Sciences of the United States of America, (3): [PMID:26483485]

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Tusamitamab (anti-CEACAM5)

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

质检证书（CoA,COO,BSE/TSE 和分析图谱)

可替换产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

Tusamitamab (anti-CEACAM5)

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

质检证书（CoA,COO,BSE/TSE 和分析图谱)

相关产品

可替换产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器