货号 (SKU)

包装规格

是否现货

价格

数量

Ab176218-100μg

100μg

现货

Ab176218-1mg

1mg

现货

Ab176218-5mg

5mg

现货

Ab176218-10mg

10mg

期货

基本信息

产品名称	PF-06342674 (anti-IL-7Ra)
别名	CD 127 antibody \| CD127 antibody \| CD127 antigen antibody \| CDw127 antibody \| IL 7R alpha antibody \| IL 7R antibody \| IL-7 receptor subunit alpha antibody \| IL-7R subunit alpha antibody \| IL-7R-alpha antibody \| IL-7RA antibody \| IL7R antibody \| IL7RA anti
英文别名	CDw127 \| IL-7 receptor subunit alpha \| IL-7R subunit alpha \| IL-7RA \| IL-7R-alpha
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属	人(Human)
特异性	IL7R
种属反应性	人(Human),小鼠(Mouse)
偶联	Unconjugated

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG1
轻链亚型	lambda
SDS-PAGE	28.0 kDa (Light Chain) & 49.5 kDa (Heavy Chain), under reducing conditions; 176.3 kDa, under non-reducing conditions.
纯化方法	Protein A purified
纯度	>95%
物理外观	Liquid
储存缓冲液	Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
分子类型	抗体

关联靶点（人）

IL7R Tbio 白细胞介素-7 受体亚基 α(Interleukin-7 receptor subunit alpha) (0 活性数据)

点击查看靶蛋白信息： IL7R

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: PF-06342674 (anti-IL-7Ra) (Ab176218)

PF-06342674 (anti-IL-7Ra) (Ab176218) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling IL-7Ra with PF-06342674 (anti-IL-7Ra) (Ab176218) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Flow Cytometry: PF-06342674 (anti-IL-7Ra) (Ab176218)

PF-06342674 (anti-IL-7Ra) (Ab176218) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling IL-7Ra (red) with PF-06342674 (anti-IL-7Ra) (Ab176218) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: PF-06342674 (anti-IL-7Ra) (Ab176218)

PF-06342674 (anti-IL-7Ra) (Ab176218) - Flow Cytometry
Flow Cytometry analysis of Hela cells labelling IL-7Ra (red) with PF-06342674 (anti-IL-7Ra) (Ab176218). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

SEC: PF-06342674 (anti-IL-7Ra) (Ab176218)

PF-06342674 (anti-IL-7Ra) (Ab176218) - SEC
The purity of PF-06342674 (anti-IL-7Ra) (Ab176218) is more than 95% verified by HPLC.

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

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找到5个结果

批号(Lot Number)	证书类型	货号
ZJ23F1201942	分析证书	Ab176218
ZJ23F1201943	分析证书	Ab176218
ZJ24F1214877	分析证书	Ab176218
ZJ24F1214876	分析证书	Ab176218
ZJ24F1214875	分析证书	Ab176218

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引用文献

1. Pleiman, C M CM and 5 more authors.. (1991) Organization of the murine and human interleukin-7 receptor genes: two mRNAs generated by differential splicing and presence of a type I-interferon-inducible promoter.. Molecular and cellular biology, [PMID:2038316]
2. Goodwin, R G RG and 9 more authors.. (1990) Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily.. Cell, (23): [PMID:2317865]
3. Puel, A A, Ziegler, S F SF, Buckley, R H RH and Leonard, W J WJ.. (1998) Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency.. Nature genetics, [PMID:9843216]
4. Roifman, C M CM, Zhang, J J, Chitayat, D D and Sharfe, N N.. (2000) A partial deficiency of interleukin-7R alpha is sufficient to abrogate T-cell development and cause severe combined immunodeficiency.. Blood, (15): [PMID:11023514]
5. Gregory, Simon G SG and 19 more authors.. (2007) Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis.. Nature genetics, [PMID:17660817]
6. McElroy, Craig A CA, Dohm, Julie A JA and Walsh, Scott T R ST.. (2009) Structural and biophysical studies of the human IL-7/IL-7Ralpha complex.. Structure (London, England : 1993), (14): [PMID:19141282]

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体积（添加到小瓶中）

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所需的复溶浓度

PF-06342674 (anti-IL-7Ra)

库存信息

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库存信息

基本信息

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关联靶点（人）

图片

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

PF-06342674 (anti-IL-7Ra)

库存信息

库存信息

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基本信息

产品属性

关联靶点（人）

图片

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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引用文献

溶液计算器

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稀释计算器

复溶计算器