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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab175636-100μg |
100μg |
期货 ![]() |
| |
| Ab175636-1mg |
1mg |
期货 ![]() |
| |
| Ab175636-5mg |
5mg |
期货 ![]() |
| |
| Ab175636-10mg |
10mg |
期货 ![]() |
|
| 产品名称 | Quilizumab (anti-IgE), 免疫球蛋白重常数ε抗体 |
|---|---|
| 别名 | 奎利珠单抗 | 奎利珠单抗(抗 IgE) |
| 英文别名 | Igh2 antibodyIGHE antibody | IGHEP1 antibody | Immunoglobulin heavy constant epsilon antibody | IgE | immunoglobulin heavy constant epsilon | Anti-Human NGcGM3 Recombinant Antibody |
| 规格或纯度 | 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA |
| 宿主种属 | 人(Human) |
| 特异性 | IGHE |
| 种属反应性 | 人(Human) |
| 偶联 | Unconjugated |
| 作用类型 | 抑制剂 |
| 作用机制 | 免疫球蛋白重常数ε抗体 |
| 克隆类型 | 重组抗体 |
|---|---|
| Format | Whole IgG |
| 亚型 | Human IgG1 |
| 轻链亚型 | kappa |
| SDS-PAGE | 146.5 kDa |
| 纯化方法 | Protein A purified |
| 物理外观 | Liquid |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | -80℃储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
| CAS编号和信息 | 1228538-47-3 |
| 分子类型 | 抗体 |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
¥559.90
¥247.92
¥669.90
| 1. Gauvreau GM, Harris JM, Boulet LP, Scheerens H, Fitzgerald JM, Putnam WS, Cockcroft DW, Davis BE, Leigh R, Zheng Y et al.. (2014) Targeting membrane-expressed IgE B cell receptor with an antibody to the M1 prime epitope reduces IgE production.. Sci Transl Med, 6 (243): (243ra85). [PMID:24990880] |
| 2. Pennington LF, Gasser P, Brigger D, Guntern P, Eggel A, Jardetzky TS. (2021) Structure-guided design of ultrapotent disruptive IgE inhibitors to rapidly terminate acute allergic reactions.. J Allergy Clin Immunol, [PMID:33991582] [10.1016/j.jaci.2021.03.050] |
| 3. Kolkhir P, Altrichter S, Munoz M, Hawro T, Maurer M. (2020) New treatments for chronic urticaria.. Ann Allergy Asthma Immunol, 124 (1): (2-12). [PMID:31446134] |