货号 (SKU)

包装规格

是否现货

价格

数量

Ab126844-10μl

10μl

现货

Ab126844-50μl

50μL

现货

Ab126844-100μl

100μL

现货

Ab126844-1ml

1ml

期货

基本信息

产品名称	SDHA Mouse mAb
别名	SDHA抗体 \| 鼠抗人SDHA 抗体 \| 琥珀酸脱氢酶复合体A亚基(SDHA)单克隆抗体 \| SDHA 小鼠 mAb
英文别名	CMD1GG antibody \| DHSA_HUMAN antibody \| Flavoprotein subunit of complex II antibody \| Fp antibody \| PGL5 antibody \| SDH 2 antibody \| SDH1 antibody \| SDH2 antibody \| SDHA antibody \| SDHF antibody \| Succinate dehydrogenase [ubiquinone] flavoprotein subunit
规格或纯度	无载体, ExactAb™, 无叠氮钠, 已验证, 高性能, 见COA
宿主种属	小鼠(Mouse)
特异性	SDHA
种属反应性	人(Human),大鼠(Rat),小鼠(Mouse)
免疫原	Recombinant SDHA expressed in E.coli (AA 4-300)
阳性对照	WB: Hep G2, HeLa, MCF7, A549, LNCaP, HEK293, NIH/3T3 and C6 cell lysates. ICC/IF: HeLa cells.
偶联	Unconjugated

产品属性

克隆类型	单克隆抗体
克隆号	C2
Format	Whole IgG
亚型	Mouse IgG2a
轻链亚型	kappa
SDS-PAGE	150 kDa
纯化方法	Protein A and Protein G purified
物理外观	Liquid
储存缓冲液	10mM PBS, 50% Glycerol, 0.05% Proclin 300, pH7.4
防腐剂	0.05% Proclin 300
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	4℃ 短期储存（1-2 周）。-20℃长期保存（24 个月）。收货后建议分装。避免冷冻/解冻循环。
分子类型	抗体

关联靶点（人）

SDHA Tbio 琥珀酸脱氢酶[泛醌]黄素蛋白亚基，线粒体(Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial) (0 活性数据)

点击查看靶蛋白信息： SDHA

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Western Blot: SDHA Mouse mAb (Ab126844)

SDHA Mouse mAb (Ab126844) - Western Blot
All lanes: SDHA Mouse mAb (Ab126844) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution

Predicted band size: 70 kDa
Observed band size: 66 kDa
Exposure time: 2.5 s

IF/ICC: SDHA Mouse mAb (Ab126844)

SDHA Mouse mAb (Ab126844) - IF/ICC
FITC staining on IF
Samples: Human HeLa cells
Primary Ab: 30 µg/mL SDHA Mouse mAb (Ab126844)
Second Ab: 2 µg/mL FITC-Linked Caprine Anti-Mouse IgG Polyclonal Antibody.

应用

应用名称	稀释比例
IF/ICC	5-30 µg/mL
WB	0.01-2 µg/mL

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到3个结果

批号(Lot Number)	证书类型	货号
ZJ23F0901138	分析证书	Ab126844
ZJ23F0901139	分析证书	Ab126844
ZJ24F0505914	分析证书	Ab126844

技术文档和文章

石蜡样品的免疫组化染色方案（IHC-P）

Categories: 实验方案（Protocols）

探索主题:

单克隆抗体石蜡切片免疫组化染色

细胞内ELISA实验方案

Categories: 实验方案（Protocols）

探索主题:

单克隆抗体多克隆抗体细胞内酶联免疫吸附实验细胞印迹蛋白定量辣根过氧化物酶标记二抗

In-cell ELISA protocol

Categories: 实验方案（Protocols）

探索主题:

Monoclonal antibodies In-cell ELISA Cytoblot Protein quantification HRP-Conjugated Secondary Antibodies Polyclonal Antibodies

In-cell ELISA protocol

Categories: 实验方案（Protocols）

探索主题:

Monoclonal antibodies In-cell ELISA Cytoblot Protein quantification HRP-Conjugated Secondary Antibodies Polyclonal Antibodies

叠氮化钠去除实验

Categories: 实验方案（Protocols）

探索主题:

重组抗体叠氮化钠去除抗体纯化葡聚糖凝胶G-25 无叠氮化钠抗体

Sodium Azide Removal Protocol

Categories: 实验方案（Protocols）

探索主题:

Recombinant antibody Sodium Azide Removal Antibody Purification Sephadex G-25 Sodium Azide-Free Antibody

引用文献

1. Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M. (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions.. Science, 325 (5942): (834-40). [PMID:19608861]
2. G Herma Renkema,Saskia B Wortmann,Roel J Smeets,Hanka Venselaar,Marion Antoine,Gepke Visser,Tawfeg Ben-Omran,Lambert P van den Heuvel,Henri J L M Timmers,Jan A Smeitink,Richard J T Rodenburg. (2014-05-02) SDHA mutations causing a multisystem mitochondrial disease: novel mutations and genetic overlap with hereditary tumors.. European journal of human genetics : EJHG, 23 ((2)): (202-209). [PMID:24781757]
3. Bourgeron, T T and 7 more authors.. (1995) Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency.. Nature genetics, [PMID:7550341]
4. Hirawake, H H, Wang, H H, Kuramochi, T T, Kojima, S S and Kita, K K.. (1994) Human complex II (succinate-ubiquinone oxidoreductase): cDNA cloning of the flavoprotein (Fp) subunit of liver mitochondria.. Journal of biochemistry, [PMID:7798181]
5. Morris, A A AA, Farnsworth, L L, Ackrell, B A BA, Turnbull, D M DM and Birch-Machin, M A MA.. (1994) The cDNA sequence of the flavoprotein subunit of human heart succinate dehydrogenase.. Biochimica et biophysica acta, (29): [PMID:8142412]
6. Parfait, B B and 5 more authors.. (2000) Compound heterozygous mutations in the flavoprotein gene of the respiratory chain complex II in a patient with Leigh syndrome.. Human genetics, [PMID:10746566]
7. Birch-Machin, M A MA, Taylor, R W RW, Cochran, B B, Ackrell, B A BA and Turnbull, D M DM.. (2000) Late-onset optic atrophy, ataxia, and myopathy associated with a mutation of a complex II gene.. Annals of neurology, [PMID:10976639]
8. Van Coster, Rudy R and 9 more authors.. (2003) Homozygous Gly555Glu mutation in the nuclear-encoded 70 kDa flavoprotein gene causes instability of the respiratory chain complex II.. American journal of medical genetics. Part A, (1): [PMID:12794685]
9. Aboulaich, Nabila N, Vainonen, Julia P JP, Strålfors, Peter P and Vener, Alexander V AV.. (2004) Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes.. The Biochemical journal, (15): [PMID:15242332]
10. Schmutz, Jeremy J and 75 more authors.. (2004) The DNA sequence and comparative analysis of human chromosome 5.. Nature, (16): [PMID:15372022]
11. Hao, Huai-Xiang HX and 13 more authors.. (2009) SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma.. Science (New York, N.Y.), (28): [PMID:19628817]
12. Burnichon, Nelly N and 13 more authors.. (2010) SDHA is a tumor suppressor gene causing paraganglioma.. Human molecular genetics, (1): [PMID:20484225]
13. Levitas, Aviva A and 8 more authors.. (2010) Familial neonatal isolated cardiomyopathy caused by a mutation in the flavoprotein subunit of succinate dehydrogenase.. European journal of human genetics : EJHG, [PMID:20551992]
14. Ogura, Masato; Yamaki, Junko; Homma, Miwako K and Homma, Yoshimi.. (2012) Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components.. The Biochemical journal, (15): [PMID:22823520]
15. Alston, Charlotte L CL and 12 more authors.. (2012) Recessive germline SDHA and SDHB mutations causing leukodystrophy and isolated mitochondrial complex II deficiency.. Journal of medical genetics, [PMID:22972948]
16. Sciacovelli, Marco M and 12 more authors.. (2013) The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase.. Cell metabolism, (4): [PMID:23747254]
17. Helman, Guy G and 13 more authors.. (2016) Magnetic resonance imaging spectrum of succinate dehydrogenase-related infantile leukoencephalopathy.. Annals of neurology, [PMID:26642834]
18. Courage, Carolina C and 6 more authors.. (2017) SDHA mutation with dominant transmission results in complex II deficiency with ocular, cardiac, and neurologic involvement.. American journal of medical genetics. Part A, [PMID:27683074]
19. Lahiri, Amit A, Hedl, Matija M, Yan, Jie J and Abraham, Clara C.. (2017) Human LACC1 increases innate receptor-induced responses and a LACC1 disease-risk variant modulates these outcomes.. Nature communications, (8): [PMID:28593945]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

体积

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)

浓度 2 (C2)

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度

SDHA Mouse mAb

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

技术文档和文章

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

SDHA Mouse mAb

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

技术文档和文章

相关产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器