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Recombinant MMP2 Antibody

Recombinant MMP2 Antibody

级别和纯度:

见COA

应用:

宿主种属: 兔(Rabbit)
种属反应性: 人(Human), 大鼠(Rat), 小鼠(Mouse)
亚型: Rabbit IgG
偶联: Unconjugated

有货

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货号 (SKU)	包装规格	是否现货
Ab115653-10μl	10μl	现货
Ab115653-50μl	50μL	现货
Ab115653-100μl	100μL	现货
Ab115653-1ml	1ml	期货

查看相关系列

点击查看靶蛋白信息: MMP2

Accession#:P08253 (3) CLG4 (1) CLG4A (1) Gene ID:4313 (3) MMP2 (3)

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基本信息

产品名称	Recombinant MMP2 Antibody
别名	Anti-MMP2抗体 \| MMP2抗体 \| MMP2 重组抗体
英文别名	72 kDa gelatinase \| CLG4 \| CLG4A72 kDa type IV collagenase \| collagenase type IV-A \| EC 3.4.24 \| EC 3.4.24.24 \| Gelatinase A \| matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IVcollagenase) \| matrix metalloproteinase 2 (gelatinase A,
规格或纯度	重组, ExactAb™, 已验证, 见COA
生化机理	Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly- -Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels.
宿主种属	兔(Rabbit)
特异性	MMP2
种属反应性	人(Human),大鼠(Rat),小鼠(Mouse)
免疫原	A synthetic peptide derived from human MMP2 (AA 100-139)
阳性对照	WB, Mouse liver lysates. IHC: Human breast adenocarcinoma tissue.
偶联	Unconjugated

产品属性

克隆类型	重组抗体
Format	Whole IgG
轻链亚型	kappa
SDS-PAGE	150 kDa
纯化方法	Protein A purified
物理外观	Liquid
储存缓冲液	10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH7.4
防腐剂	0.02% Sodium azide
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	4°C 运输。发货后，分装并储存于 -20°C 或 -80°C。避免反复冻融循环。
分子类型	抗体

关联靶点（人）

MMP2 Tchem 72 kDa IV 型胶原酶(72 kDa type IV collagenase) (0 活性数据)

点击查看靶蛋白信息： MMP2

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Western Blot: Recombinant MMP2 Antibody (Ab115653)

Recombinant MMP2 Antibody (Ab115653) - Western Blot
All lanes: Recombinant MMP2 Antibody (Ab115653) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/10000 dilution
Predicted band size: 74 kDa
Observed band size: 61 kDa
Exposure time: 1.7 s

IHC: Recombinant MMP2 Antibody (Ab115653)

Recombinant MMP2 Antibody (Ab115653) - IHC
Immunohistochemical analysis of paraffin-embedded human breast adenocarcinoma, using Recombinant MMP2 Antibody (Ab115653).

应用