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MCP4 Antibody

    级别和纯度:
  • 见COA
    应用:
  • WB
  • 宿主种属: 兔(Rabbit)
  • 种属反应性: 人(Human)
  • 亚型: Rabbit IgG
  • 偶联: Unconjugated
有货

库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
Ab114614-10μl
10μl 期货 Stock Image
Ab114614-50μl
50μL 期货 Stock Image
Ab114614-100μl
100μL 期货 Stock Image
Ab114614-1ml
1ml 期货 Stock Image

基本信息

产品名称 MCP4 Antibody
别名 单核细胞趋化蛋白4(MCP4)多克隆抗体
英文别名 C-C motif chemokine 13 antibody | CCL13 antibody | CCL13_HUMAN antibody | Chemokine (C C motif) ligand 13antibody | CK beta 10 antibody | CK-beta-10 antibody | CKb10 antibody | MCP-4 antibody | MGC17134 antibody | Monocyte chemoattractant protein 4 antibo
规格或纯度 见COA
生化机理 Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
宿主种属 兔(Rabbit)
特异性 CCL13
种属反应性 人(Human)
免疫原 A synthetic peptide derived from human CCL13 (AA 20-100)
阳性对照 WB:SW480 lysates.  
偶联 Unconjugated

产品属性

克隆类型 多克隆抗体
Format Whole IgG
亚型 Rabbit IgG
SDS-PAGE 150 kDa
纯化方法 Immunogen affinity purified
物理外观 Liquid
储存缓冲液 10mM PBS, 50% Glycerol, 0.5% BSA, 0.02% Sodium azide, pH7.2.
防腐剂 0.02% Sodium azide
浓度 见COA
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 短期储存4℃(1-2周);长期储存-20℃(12个月);收货后建议分装,避免反复冻融。
分子类型 抗体

关联靶点(人)

CCL13 Tbio CC 基序趋化因子 13(C-C motif chemokine 13) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

应用

应用名称 稀释比例
WB

1/500-1/2000

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

引用文献

1. Uguccioni, M M and 10 more authors..  (1996)  Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin..  The Journal of experimental medicine,  (1): [PMID:8642349]
2. Garcia-Zepeda, E A EA and 7 more authors..  (1996)  Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3..  Journal of immunology (Baltimore, Md. : 1950),  (15): [PMID:8955214]
3. Godiska, R R and 5 more authors..  (1997)  Monocyte chemotactic protein-4: tissue-specific expression and signaling through CC chemokine receptor-2..  Journal of leukocyte biology,  [PMID:9060459]
4. Berkhout, T A TA and 18 more authors..  (1997)  Cloning, in vitro expression, and functional characterization of a novel human CC chemokine of the monocyte chemotactic protein (MCP) family (MCP-4) that binds and signals through the CC chemokine receptor 2B..  The Journal of biological chemistry,  (27): [PMID:9195948]
5. Hein, H H and 5 more authors..  (1999)  Genomic organization, sequence analysis and transcriptional regulation of the human MCP-4 chemokine gene (SCYA13) in dermal fibroblasts: a comparison to other eosinophilic beta-chemokines..  Biochemical and biophysical research communications,  (16): [PMID:10049733]
6. Zody, Michael C MC and 73 more authors..  (2006)  DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage..  Nature,  (20): [PMID:16625196]
7. Barinka, Cyril C, Prahl, Adam A and Lubkowski, Jacek J..  (2008)  Structure of human monocyte chemoattractant protein 4 (MCP-4/CCL13)..  Acta crystallographica. Section D, Biological crystallography,  [PMID:18323622]

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