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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab114614-10μl |
10μl |
期货 ![]() |
| |
| Ab114614-50μl |
50μL |
期货 ![]() |
| |
| Ab114614-100μl |
100μL |
期货 ![]() |
| |
| Ab114614-1ml |
1ml |
期货 ![]() |
|
| 产品名称 | MCP4 Antibody |
|---|---|
| 别名 | 单核细胞趋化蛋白4(MCP4)多克隆抗体 |
| 英文别名 | C-C motif chemokine 13 antibody | CCL13 antibody | CCL13_HUMAN antibody | Chemokine (C C motif) ligand 13antibody | CK beta 10 antibody | CK-beta-10 antibody | CKb10 antibody | MCP-4 antibody | MGC17134 antibody | Monocyte chemoattractant protein 4 antibo |
| 规格或纯度 | 见COA |
| 生化机理 | Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens. |
| 宿主种属 | 兔(Rabbit) |
| 特异性 | CCL13 |
| 种属反应性 | 人(Human) |
| 免疫原 | A synthetic peptide derived from human CCL13 (AA 20-100) |
| 阳性对照 | WB:SW480 lysates. |
| 偶联 | Unconjugated |
| 克隆类型 | 多克隆抗体 |
|---|---|
| Format | Whole IgG |
| 亚型 | Rabbit IgG |
| SDS-PAGE | 150 kDa |
| 纯化方法 | Immunogen affinity purified |
| 物理外观 | Liquid |
| 储存缓冲液 | 10mM PBS, 50% Glycerol, 0.5% BSA, 0.02% Sodium azide, pH7.2. |
| 防腐剂 | 0.02% Sodium azide |
| 浓度 | 见COA |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 短期储存4℃(1-2周);长期储存-20℃(12个月);收货后建议分装,避免反复冻融。 |
| 分子类型 | 抗体 |
| 应用名称 | 稀释比例 |
|---|---|
| WB | 1/500-1/2000 |
| 1. Uguccioni, M M and 10 more authors.. (1996) Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin.. The Journal of experimental medicine, (1): [PMID:8642349] |
| 2. Garcia-Zepeda, E A EA and 7 more authors.. (1996) Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3.. Journal of immunology (Baltimore, Md. : 1950), (15): [PMID:8955214] |
| 3. Godiska, R R and 5 more authors.. (1997) Monocyte chemotactic protein-4: tissue-specific expression and signaling through CC chemokine receptor-2.. Journal of leukocyte biology, [PMID:9060459] |
| 4. Berkhout, T A TA and 18 more authors.. (1997) Cloning, in vitro expression, and functional characterization of a novel human CC chemokine of the monocyte chemotactic protein (MCP) family (MCP-4) that binds and signals through the CC chemokine receptor 2B.. The Journal of biological chemistry, (27): [PMID:9195948] |
| 5. Hein, H H and 5 more authors.. (1999) Genomic organization, sequence analysis and transcriptional regulation of the human MCP-4 chemokine gene (SCYA13) in dermal fibroblasts: a comparison to other eosinophilic beta-chemokines.. Biochemical and biophysical research communications, (16): [PMID:10049733] |
| 6. Zody, Michael C MC and 73 more authors.. (2006) DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.. Nature, (20): [PMID:16625196] |
| 7. Barinka, Cyril C, Prahl, Adam A and Lubkowski, Jacek J.. (2008) Structure of human monocyte chemoattractant protein 4 (MCP-4/CCL13).. Acta crystallographica. Section D, Biological crystallography, [PMID:18323622] |