DNA Polymerase iota Mouse mAb

级别和纯度:

应用:

有货

关闭

关闭

关闭

关闭

货号 (SKU)	包装规格	是否现货
Ab100101-10μl	10μl	期货
Ab100101-50μl	50μL	期货
Ab100101-100μl	100μL	期货
Ab100101-1ml	1ml	期货

查看相关系列

Accession#: Q9UNA4 (1) DNA Polymerase iota (1) Gene ID: 11201 (1) POLI (1)

基本信息

产品名称	DNA Polymerase iota Mouse mAb
别名	DNA Polymerase iota抗体 \| DNA Polymerase iota单克隆抗体 \| DNA聚合酶I抗体
英文别名	DNA polymerase iota antibody \| Eta 2 antibody \| Eta2 antibody \| POLI antibody \| POLI_HUMAN antibody \| Polymerase (DNA directed) iota antibody \| RAD 30B antibody \| RAD30 homolog B antibody \| RAD30 \| RAD30B antibody \| RAD3OB antibody \| S. cerevisiae \| homol
规格或纯度	见COA
生化机理	Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity.
宿主种属	小鼠(Mouse)
特异性	DNA Polymerase iota
种属反应性	人(Human)
免疫原	Recombinant protein of human DNA Polymerase iota (AA 458-740) produced in E.coli.
阳性对照	WB: HEK293T transfected with pCMV6-ENTRY POLI cDNA for 48 hrs; HepG2, HeLa, SVT2, A549 lysates. IHC: Human ovary adenocarcinoma tissue.
偶联	Unconjugated

产品属性

克隆类型	单克隆抗体
Format	Whole IgG
SDS-PAGE	150 kDa
纯化方法	Protein G purified
物理外观	Liquid
储存缓冲液	10mM PBS, 50% Glycerol, 1% BSA, 0.02% Sodium azide, pH 7.3.
防腐剂	0.02% Sodium azide
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	短期储存4℃（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。
分子类型	抗体