Recombinant CD31 Antibody

COA

级别和纯度:

重组

已验证

ExactAb™

见COA

应用:

宿主种属: 兔(Rabbit)
种属反应性: 人(Human)
亚型: Rabbit IgG
偶联: Unconjugated

有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货
Ab094534-10μl	10μl	现货
Ab094534-50μl	50μL	现货
Ab094534-100μl	100μL	现货
Ab094534-1ml	1ml	期货

查看相关系列

点击查看靶蛋白信息: PECAM1

Accession#:P16284 (8) CD31 (0) endoCAM (1) Gene ID:5175 (8) PECAM1 (9)

Skip to the end of the images gallery

Skip to the beginning of the images gallery

基本信息

产品名称	Recombinant CD31 Antibody
别名	血小板内皮细胞黏附分子1抗体 \| 血小板内皮细胞黏附分子1单克隆抗体 \| 血小板内皮细胞黏附分子1重组单克隆抗体 \| CD31抗体 \| CD31单克隆抗体 \| CD31重组单克隆抗体 \| PECAM1抗体 \| PECAM1单克隆抗体 \| PECAM1重组单克隆抗体
英文别名	CD31 antigen \| CD31 \| CD31/EndoCAM \| EndoCAM \| FLJ34100 \| FLJ58394 \| GPIIA' \| PECA1 \| adhesion molecule \| PECAM1 \| PECAM-1 \| PECAM-1, CD31/EndoCAM \| platelet endothelial cell adhesion molecule \| platelet endothelial cell adhesion molecule-1 \| platelet/end
规格或纯度	重组, ExactAb™, 已验证, 见COA
生化机理	Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Isoform Delta15 is unable to protect against apoptosis. Modulates BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC).
宿主种属	兔(Rabbit)
特异性	PECAM1
种属反应性	人(Human)
免疫原	A synthetic peptide derived from human CD31(AA 150-200)
阳性对照	WB: Jurkat and HUVEC cell lysates. IHC: Human kidney tissue.
偶联	Unconjugated

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Rabbit IgG
轻链亚型	kappa
SDS-PAGE	150 kDa
纯化方法	Protein A purified
物理外观	Liquid
储存缓冲液	10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4
防腐剂	0.02% Sodium azide
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融。
分子类型	抗体

关联靶点（人）

PECAM1 Tbio 血小板内皮细胞粘附分子(Platelet endothelial cell adhesion molecule) (0 活性数据)

点击查看靶蛋白信息： PECAM1

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Western Blot: Recombinant CD31 Antibody (Ab094534)

Recombinant CD31 Antibody (Ab094534) - Western Blot
All lanes: Recombinant CD31 Antibody (Ab094534) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 83 kDa
Observed band size: 118 kDa
Exposure time: 89.0 s

IHC: Recombinant CD31 Antibody (Ab094534)

Recombinant CD31 Antibody (Ab094534) - IHC
Immunohistochemical analysis of paraffin-embedded human kidney using Recombinant CD31 Antibody (Ab094534). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

应用

应用名称	稀释比例
IHC	1/50-1/200
WB	1/500-1/2000

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到5个结果

批号(Lot Number)	证书类型	货号
ZJ25F0723570	分析证书	Ab094534
ZJ25F0723569	分析证书	Ab094534
ZJ25F0723568	分析证书	Ab094534
ZJ24F0910088	分析证书	Ab094534
ZJ24F0910087	分析证书	Ab094534