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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| A105534-5mg |
5mg |
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| A105534-25mg |
25mg |
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| A105534-50mg |
50mg |
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| A105534-100mg |
100mg |
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| A105534-250mg |
250mg |
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| A105534-500mg |
500mg |
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| A105534-1g |
1g |
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| 产品名称 | 抑肽酶 来源于牛肺, 纤溶酶原抑制剂 |
|---|---|
| 别名 | 抑肽酶 | 牛胰胰蛋白酶抑制剂 | 胰蛋白酶抑制剂(碱性) |
| 英文别名 | Aprotinin from bovine lung | CCG-270718 | APROTININ | Traskolan | Antilysin | J-200086 | Bovine Pancreatic Trypsin Inhibitor | AKOS024457997 | Traskolan | Bovine Pancreatic Trypsin Inhibitor |
| 规格或纯度 | EnzymoPure™, ≥3.0 EPU/mg; 3-8 TIU/mg;6512 Da |
| 生化机理 | 抑肽酶是一种竞争性丝氨酸蛋白酶抑制剂,可与酶的活性位点组成稳定的复合酶并同时对其进行封闭。 这种结合是可逆的,而且绝大多数抑肽酶-蛋白酶复合物可在极端的pH >10 or < 3水平时发生解离。 从结构上来说,抑肽酶是一种来自牛肺的单体球状蛋白,由58个氨基酸组成并排列在具有三个交联二硫键的单个多肽链中。 |
| 产品介绍 |
抑肽酶是一种58个氨基酸长的蛋白,计算的分子量为6512 Da,可作为丝氨酸蛋白酶抑制剂。抑肽酶也称为牛胰胰蛋白酶抑制剂(BPTI),可抑制丝氨酸蛋白酶,例如胰凝乳蛋白酶,激肽释放酶,纤溶酶和胰蛋白酶。
细胞定位:Secreted. 应用 抑肽酶被大量用作胰蛋白酶抑制剂。
Aprotinin is a 58 amino acid-long protein, with a calculated molecular weight of 6512 Da, that acts as a serine protease inhibitor. Known also as bovine pancreatic trypsin inhibitor (BPTI), aprotinin inhibits serine proteases such as chymotrypsin, kallikrein, plasmin and trypsin. Application |
| 生物活性 | ≥3.0 EPU/mg; 3-8 TIU/mg |
| 种属 | 牛(Bovine) |
| Accession # | P00974 |
| 来源 | 天然 |
| 作用类型 | 抑制剂 |
| 作用机制 | 纤溶酶原抑制剂 |
| 物理形态 | 冻干(Lyophilized) |
|---|---|
| 浓度 | ≥3.0 EPU/mg; 3-8 TIU/mg;6512 Da |
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| CAS编号和信息 | 9087-70-1 |
| 单位定义 | 能抑制一个胰蛋白酶单位[每秒钟能水解1 μmol的N-苯甲酰-L-精氨酸乙酯(BAEE)为一个胰蛋白酶单位(microkatal)]的活力称为一个抑肽酶活力单位(EPU)。每1EPU的抑肽酶相当于1800KIU。 一个胰蛋白酶抑制剂单位(TIU)可将两个胰蛋白酶单位的活性降低50%,而其中一个胰蛋白酶单位在pH 7.8和25℃下可每分钟水解1.0 μmol的N-α-苯甲酰基-DL-精氨酸对硝基苯胺。另一种常用的单位是KIU,而1 TIU = 1,300 KIU。 |
| 分子类型 | 蛋白质 |
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| 批号(Lot Number) | 证书类型 | 货号 |
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| 分析证书 | A105534 | |
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| 分析证书 | A105534 | |
| 分析证书 | A105534 | |
| 分析证书 | A105534 | |
| 分析证书 | A105534 | |
| 分析证书 | A105534 | |
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| 分析证书 | A105534 |
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| 1. Author': None. (2022) Late-Breaking Abstracts for ECO2022.. Obes Facts, 15 Suppl 1 (241-286). [PMID:35500565] |
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| 7. Jia-Yu Shi, Hai-Yan Pan, Kun Liu, Min Pan, Guo-Jun Si. (2020) Expression of ectopic trypsin in atherosclerotic plaques and the effects of aprotinin on plaque stability. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 690 (108460). [PMID:32603715] [10.1016/j.abb.2020.108460] |
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| 9. Yunhua Zhang, Jinyun Ji, Xiao Zhao, Ruoheng Jin, Jianhong Li, Hu Wan. (2017) Expression, purification and enzymatic properties of a β-N-acetylhexosaminidase from brown planthopper, Nilaparvata lugens. JOURNAL OF ASIA-PACIFIC ENTOMOLOGY, 20 (1340). [10.1016/j.aspen.2017.10.005] |
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