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Tregalizumab (anti-CD4) - Primary antibody, specific to CD4, >95%, high purity, Human IgG1, AGONIST of T-cell surface antigen CD4 agonist, AGONIST of T-cell surface antigen CD4 agonist

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab170850
Grouped product items
SKU Size
Availability
Price Qty
Ab170850-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
Ab170850-1mg
1mg
5
$417.90
Ab170850-5mg
5mg
1
$1,077.90
Ab170850-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,707.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Tregalizumab (anti-CD4) - Primary antibody, specific to CD4, >95%, high purity, Human IgG1, AGONIST of T-cell surface antigen CD4 agonist
Synonyms CD 4 antibody | CD4 (L3T4) antibody | CD4 antibody | CD4 antigen (p55) antibody | CD4 antigen antibody | CD4 molecule antibody | CD4 receptor antibody | CD4+ Lymphocyte deficiency, included antibody | CD4_HUMAN antibody | CD4mut antibody | L3T4 antibody |
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD4
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type AGONIST
Mechanism of action AGONIST of T-cell surface antigen CD4 agonist
Product Description

Tregalizumab (anti-CD4) is a humanized anti-human CD4 monoclonal antibody (IgG1 type) that selectively activates the suppressive properties of regulatory T cells (Tregs) in vitro. Tregalizumab (anti-CD4) can be used in the research of autoimmune diseases (resulting from insufficient Treg activity) and allergies.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 27.2 kDa (Light Chain) & 51.5 kDa (Heavy Chain), under reducing conditions; 165.5 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1207446-68-1

Associated Targets(Human)

CD4 Tclin T-cell surface glycoprotein CD4 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Tregalizumab (anti-CD4) (Ab170850) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD4 with Tregalizumab (anti-CD4) (Ab170850) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Tregalizumab (anti-CD4) (Ab170850) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD4 (red) with Tregalizumab (anti-CD4) (Ab170850) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.


Tregalizumab (anti-CD4) (Ab170850) - SEC
The purity of Tregalizumab (anti-CD4) (Ab170850) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1202088 Certificate of Analysis Dec 20, 2023 Ab170850
ZJ23F1202087 Certificate of Analysis Dec 20, 2023 Ab170850

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