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Tesnatilimab (anti-NKG2D) - Primary antibody, specific to KLRK1, >95%, high purity, Human IgG4SP

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab176555
Grouped product items
SKU Size
Availability
Price Qty
Ab176555-100μg
100μg
10
$89.90
Ab176555-1mg
1mg
4
$429.90
Ab176555-5mg
5mg
1
$1,119.90
Ab176555-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,789.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Tesnatilimab (anti-NKG2D) - Primary antibody, specific to KLRK1, >95%, high purity, Human IgG4SP
Synonyms CD314 antibody | CD314 antigen antibody | D12S2489E antibody | Killer cell lectin like receptor subfamily K member 1 antibody | Killer cell lectin-like receptor subfamily K member 1 antibody | KLR antibody | KLRC4 KLRK1 readthrough antibody | KLRK1 antibo
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity KLRK1
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Tesnatilimab (anti-NKG2D) is a human IgG4 monoclonal antibody that acts on the immune activating receptor NKG2D and has potential immunomodulatory and anti-inflammatory activity. Tesnatilimab (anti-NKG2D) can be used in the study of inflammatory bowel disease (IBD).
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG4SP
Light Chain Type kappa
SDS-PAGE 26.6 kDa (Light Chain) & 51.0 kDa (Heavy Chain), under reducing conditions; 165.7 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2242758-08-1

Associated Targets(Human)

KLRK1 Tbio NKG2-D type II integral membrane protein (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Tesnatilimab (anti-NKG2D) (Ab176555) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling NKG2D with Tesnatilimab (anti-NKG2D) (Ab176555) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Tesnatilimab (anti-NKG2D) (Ab176555) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling NKG2D (red) with Tesnatilimab (anti-NKG2D) (Ab176555) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

Tesnatilimab (anti-NKG2D) (Ab176555) - SEC
The purity of Tesnatilimab (anti-NKG2D) (Ab176555) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0202865 Certificate of Analysis Feb 23, 2024 Ab176555
ZJ24F0202864 Certificate of Analysis Feb 23, 2024 Ab176555
ZJ24F0202863 Certificate of Analysis Feb 23, 2024 Ab176555

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