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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab176555-100μg
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100μg |
10
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$89.90
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Ab176555-1mg
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1mg |
4
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$429.90
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Ab176555-5mg
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5mg |
1
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$1,119.90
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Ab176555-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,789.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Tesnatilimab (anti-NKG2D) - Primary antibody, specific to KLRK1, >95%, high purity, Human IgG4SP |
|---|---|
| Synonyms | CD314 antibody | CD314 antigen antibody | D12S2489E antibody | Killer cell lectin like receptor subfamily K member 1 antibody | Killer cell lectin-like receptor subfamily K member 1 antibody | KLR antibody | KLRC4 KLRK1 readthrough antibody | KLRK1 antibo |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | KLRK1 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Tesnatilimab (anti-NKG2D) is a human IgG4 monoclonal antibody that acts on the immune activating receptor NKG2D and has potential immunomodulatory and anti-inflammatory activity. Tesnatilimab (anti-NKG2D) can be used in the study of inflammatory bowel disease (IBD). |
| Isotype | Human IgG4SP |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.6 kDa (Light Chain) & 51.0 kDa (Heavy Chain), under reducing conditions; 165.7 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2242758-08-1 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Tesnatilimab (anti-NKG2D) (Ab176555) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling NKG2D with Tesnatilimab (anti-NKG2D) (Ab176555) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).
Tesnatilimab (anti-NKG2D) (Ab176555) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling NKG2D (red) with Tesnatilimab (anti-NKG2D) (Ab176555) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
Tesnatilimab (anti-NKG2D) (Ab176555) - SEC
The purity of Tesnatilimab (anti-NKG2D) (Ab176555) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Feb 23, 2024 | Ab176555 | |
| Certificate of Analysis | Feb 23, 2024 | Ab176555 | |
| Certificate of Analysis | Feb 23, 2024 | Ab176555 |
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