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Teneliximab (anti-CD40) - Primary antibody, specific to CD40, Human IgG1, PARTIAL AGONIST of Tumor necrosis factor receptor superfamily member 5 partial agonist, PARTIAL AGONIST of Tumor necrosis factor receptor superfamily member 5 partial agonist

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab183440
Grouped product items
SKU Size
Availability
 Price Qty
Ab183440-100μg
100μg
10
$59.90
Ab183440-1mg
1mg
4
$259.90
Ab183440-5mg
5mg
1
$589.90
Ab183440-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$929.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: CD40
Accession#:P25942 (33) Extrinsic Pathway (436) Gene ID:958 (32) TNFRSF5 (29)

Basic Description

Product Name Teneliximab (anti-CD40) - Primary antibody, specific to CD40, Human IgG1, PARTIAL AGONIST of Tumor necrosis factor receptor superfamily member 5 partial agonist
Synonyms AI326936 antibody | B cell associated molecule CD40 antibody | B cell surface antigen CD40 antibody | B cell-associated molecule antibody | B-cell surface antigen CD40 antibody | Bp50 antibody | CD 40 antibody | CD40 antibody | CD40 antigen (TNF receptor
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD40
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type PARTIAL AGONIST
Mechanism of action PARTIAL AGONIST of Tumor necrosis factor receptor superfamily member 5 partial agonist
Product Description

Teneliximab (anti-CD40) is a chimeric monoclonal antibody, blocks the CD40-CD40L interaction. Teneliximab (anti-CD40) has partial agonist activity resulting in some signaling through CD40 and peripheral B cell depletion.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 146.06 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 299423-37-3

Associated Targets(Human)

CD40 Tchem Tumor necrosis factor receptor superfamily member 5 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CD40 Tchem Tumor necrosis factor receptor superfamily member 5 (9 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Teneliximab (anti-CD40) (Ab183440) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD40 (red) with Teneliximab (anti-CD40) (Ab183440). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Teneliximab (anti-CD40) (Ab183440) - Flow Cytometry
Flow Cytometry analysis of U-2OS cells labelling CD40 (red) with Teneliximab (anti-CD40) (Ab183440). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Teneliximab (anti-CD40) (Ab183440) - ELISA
Immobilized Recombinant Human CD40 Protein (rp144000) at 1.0 μg/mL can bind Teneliximab (anti-CD40) (Ab183440) with the EC50 of 11.50 ng/mL.​

Teneliximab (anti-CD40) (Ab183440) - SEC
The purity of Teneliximab (anti-CD40) (Ab183440) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0505701 Certificate of Analysis May 16, 2024 Ab183440
ZJ24F0505702 Certificate of Analysis May 16, 2024 Ab183440
ZJ24F0505703 Certificate of Analysis May 16, 2024 Ab183440

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